Publications
Here is a list of over 700 publications about Heliconius and related butterfly genera. This list is drawn from a Zotero Group library called Heliconius. Feel free to join the group and you can search these references in Zotero.
166086
1
apa
50
date
year
142
https://www.heliconius.org/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A950%2C%22request_next%22%3A50%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%226PZFYSCZ%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Davies%20and%20Saccheri%22%2C%22parsedDate%22%3A%222024-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDavies%2C%20W.%2C%20%26amp%3B%20Saccheri%2C%20I.%20%282024%29.%20Evolutionary%20trajectory%20of%20phenological%20escape%20in%20a%20flowering%20plant%3A%20Mechanistic%20insights%20from%20bidirectional%20avoidance%20of%20butterfly%20egg-laying%20pressure.%20%26lt%3Bi%26gt%3BECOLOGY%20AND%20EVOLUTION%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B14%26lt%3B%5C%2Fi%26gt%3B%285%29.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.11330%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.11330%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Evolutionary%20trajectory%20of%20phenological%20escape%20in%20a%20flowering%20plant%3A%20Mechanistic%20insights%20from%20bidirectional%20avoidance%20of%20butterfly%20egg-laying%20pressure%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22WJ%22%2C%22lastName%22%3A%22Davies%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22IJ%22%2C%22lastName%22%3A%22Saccheri%22%7D%5D%2C%22abstractNote%22%3A%22Phenological%20escape%2C%20whereby%20species%20alter%20the%20timing%20of%20life-history%20events%20to%20avoid%20seasonal%20antagonists%2C%20is%20usually%20analyzed%20either%20as%20a%20potential%20evolutionary%20outcome%20given%20current%20selection%20coefficients%2C%20or%20as%20a%20realized%20outcome%20in%20response%20to%20known%20enemies.%20We%20here%20gain%20mechanistic%20insights%20into%20the%20evolutionary%20trajectory%20of%20phenological%20escape%20in%20the%20brassicaceous%20herb%20Cardamine%20pratensis%2C%20by%20comparing%20the%20flowering%20schedules%20of%20two%20sympatric%20ecotypes%20in%20different%20stages%20of%20a%20disruptive%20response%20to%20egg-laying%20pressure%20imposed%20by%20the%20pierid%20butterfly%20Anthocharis%20cardamines%2C%20whose%20larvae%20are%20pre-dispersal%20seed%20predators%20%28reducing%20realized%20fecundity%20by%20similar%20to%2070%25%29.%20When%20the%20focal%20point%20of%20highest%20intensity%20selection%20%28peak%20egg-laying%29%20occurs%20early%20in%20the%20flowering%20schedule%2C%20selection%20for%20late%20flowering%20dependent%20on%20reduced%20egg-laying%20combined%20with%20selection%20for%20early%20flowering%20dependent%20on%20reduced%20predator%20survival%20results%20in%20a%20symmetrical%20bimodal%20flowering%20curve%3B%20when%20the%20focal%20point%20occurs%20late%2C%20an%20asymmetrical%20flowering%20curve%20results%20with%20a%20large%20early%20flowering%20mode%20due%20to%20selection%20for%20reduced%20egg-laying%20augmented%20by%20selection%20for%20infested%20plants%20to%20outrun%20larval%20development%20and%20dehisce%20prior%20to%20seed-pod%20consumption.%20Unequal%20selection%20pressures%20on%20high%20and%20low%20fecundity%20ramets%2C%20due%20to%20asynchronous%20flowering%20and%20morphologically%20targeted%20%28size-dependent%29%20egg-laying%2C%20constrain%20phenological%20escape%2C%20with%20bimodal%20flowering%20evolving%20primarily%20in%20response%20to%20disruptive%20selection%20on%20high%20fecundity%20phenotypes.%20These%20results%20emphasize%20the%20importance%20of%20analyzing%20variation%20in%20selection%20coefficients%20among%20morphological%20phenotypes%20over%20the%20entire%20flowering%20schedule%20to%20predict%20how%20populations%20will%20evolve%20in%20response%20to%20altered%20phenologies%20resulting%20from%20climate%20change.%22%2C%22date%22%3A%222024%20MAY%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fece3.11330%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%222045-7758%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22W9PMW99E%22%5D%2C%22dateModified%22%3A%222025-11-11T22%3A33%3A20Z%22%7D%7D%2C%7B%22key%22%3A%22YFHDEWFR%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Ehlers%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-31%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BEhlers%2C%20S.%2C%20Blow%2C%20R.%2C%20Szczerbowski%2C%20D.%2C%20Jiggins%2C%20C.%2C%20%26amp%3B%20Schulz%2C%20S.%20%282023%29.%20Variation%20of%20Clasper%20Scent%20Gland%20Composition%20of%20Heliconius%20Butterflies%20from%20a%20Biodiversity%20Hotspot.%20%26lt%3Bi%26gt%3BChembiochem%3A%20A%20European%20Journal%20of%20Chemical%20Biology%26lt%3B%5C%2Fi%26gt%3B%2C%20e202300537.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fcbic.202300537%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fcbic.202300537%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Variation%20of%20Clasper%20Scent%20Gland%20Composition%20of%20Heliconius%20Butterflies%20from%20a%20Biodiversity%20Hotspot%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Ehlers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rachel%22%2C%22lastName%22%3A%22Blow%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daiane%22%2C%22lastName%22%3A%22Szczerbowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%22%2C%22lastName%22%3A%22Jiggins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefan%22%2C%22lastName%22%3A%22Schulz%22%7D%5D%2C%22abstractNote%22%3A%22Male%20Heliconius%20butterflies%20possess%20two%20pheromone%20emitting%20structures%2C%20wing%20androconia%20and%20abdominal%20clasper%20scent%20glands.%20The%20composition%20of%20the%20clasper%20scent%20gland%20of%20males%20of%2017%20Heliconius%20and%20Eueides%20species%20from%20an%20overlapping%20area%20in%20Ecuador%2C%20comprising%20three%20mimicry%20groups%2C%20was%20investigated%20by%20GC%5C%2FMS.%20The%20chemical%20signal%20serves%20as%20an%20anti-aphrodisiac%20signal%20that%20is%20transferred%20from%20males%20to%20females%20during%20mating%2C%20indicating%20the%20mating%20status%20of%20the%20female%20to%20prevent%20them%20from%20harassment%20by%20other%20males.%20In%20addition%2C%20the%20odour%20may%20also%20serve%20in%20predator%20defence.%20There%20is%20potential%20for%20convergence%20driven%20by%20mimicry%2C%20although%2C%20such%20convergence%20might%20be%20detrimental%20for%20species%20recognition%20of%20the%20butterflies%20within%20the%20mimicry%20ring%2C%20making%20mating%20more%20difficult.%20More%20than%20500%20compounds%20were%20detected%2C%20consisting%20of%20volatile%2C%20semi-volatile%20or%20non-volatile%20compounds%2C%20including%20terpenes%2C%20fatty%20acid%20esters%20or%20aromatic%20compounds.%20Several%20novel%20esters%20were%20identified%20by%20GC%5C%2FMS%20and%20GC%5C%2FIR%20data%2C%20microderivatisation%20and%20synthesis%2C%20including%20butyl%20%28Z%29-3-dodecenoate%20and%20other%20%28Z%29-3-alkenoates%2C%203-oxohexyl%20citronellate%20and%205-methylhexa-3%2C5-dienyl%20%28E%29-2%2C3-dihydrofarnesoate.%20The%20secretions%20were%20found%20to%20be%20species%20specific%2C%20potentially%20allowing%20for%20species%20differentiation.%20Statistical%20analysis%20of%20the%20more%20than%20500%20compounds%20showed%20differentiation%20by%20phylogenetic%20clade%20and%20species%2C%20but%20not%20by%20mimicry%20group.%22%2C%22date%22%3A%222023-08-31%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fcbic.202300537%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237650217%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221439-7633%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22B9SJYNCA%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Chakraborty%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BChakraborty%2C%20M.%2C%20Lara%2C%20A.%20G.%2C%20Dang%2C%20A.%2C%20McCulloch%2C%20K.%20J.%2C%20Rainbow%2C%20D.%2C%20Carter%2C%20D.%2C%20Ngo%2C%20L.%20T.%2C%20Solares%2C%20E.%2C%20Said%2C%20I.%2C%20Corbett-Detig%2C%20R.%20B.%2C%20Gilbert%2C%20L.%20E.%2C%20Emerson%2C%20J.%20J.%2C%20%26amp%3B%20Briscoe%2C%20A.%20D.%20%282023%29.%20Sex-linked%20gene%20traffic%20underlies%20the%20acquisition%20of%20sexually%20dimorphic%20UV%20color%20vision%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BProceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B120%26lt%3B%5C%2Fi%26gt%3B%2833%29%2C%20e2301411120.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1073%5C%2Fpnas.2301411120%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1073%5C%2Fpnas.2301411120%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Sex-linked%20gene%20traffic%20underlies%20the%20acquisition%20of%20sexually%20dimorphic%20UV%20color%20vision%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mahul%22%2C%22lastName%22%3A%22Chakraborty%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angelica%20Guadalupe%22%2C%22lastName%22%3A%22Lara%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrew%22%2C%22lastName%22%3A%22Dang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kyle%20J.%22%2C%22lastName%22%3A%22McCulloch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dylan%22%2C%22lastName%22%3A%22Rainbow%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Carter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Luna%20Thanh%22%2C%22lastName%22%3A%22Ngo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Edwin%22%2C%22lastName%22%3A%22Solares%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Iskander%22%2C%22lastName%22%3A%22Said%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Russell%20B.%22%2C%22lastName%22%3A%22Corbett-Detig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lawrence%20E.%22%2C%22lastName%22%3A%22Gilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20J.%22%2C%22lastName%22%3A%22Emerson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adriana%20D.%22%2C%22lastName%22%3A%22Briscoe%22%7D%5D%2C%22abstractNote%22%3A%22The%20acquisition%20of%20novel%20sexually%20dimorphic%20traits%20poses%20an%20evolutionary%20puzzle%3A%20How%20do%20new%20traits%20arise%20and%20become%20sex-limited%3F%20Recently%20acquired%20color%20vision%2C%20sexually%20dimorphic%20in%20animals%20like%20primates%20and%20butterflies%2C%20presents%20a%20compelling%20model%20for%20understanding%20how%20traits%20become%20sex-biased.%20For%20example%2C%20some%20Heliconius%20butterflies%20uniquely%20possess%20UV%20%28ultraviolet%29%20color%20vision%2C%20which%20correlates%20with%20the%20expression%20of%20two%20differentially%20tuned%20UV-sensitive%20rhodopsins%2C%20UVRh1%20and%20UVRh2.%20To%20discover%20how%20such%20traits%20become%20sexually%20dimorphic%2C%20we%20studied%20Heliconius%20charithonia%2C%20which%20exhibits%20female-specific%20UVRh1%20expression.%20We%20demonstrate%20that%20females%2C%20but%20not%20males%2C%20discriminate%20different%20UV%20wavelengths.%20Through%20whole-genome%20shotgun%20sequencing%20and%20assembly%20of%20the%20H.%20charithonia%20genome%2C%20we%20discovered%20that%20UVRh1%20is%20present%20on%20the%20W%20chromosome%2C%20making%20it%20obligately%20female-specific.%20By%20knocking%20out%20UVRh1%2C%20we%20show%20that%20UVRh1%20protein%20expression%20is%20absent%20in%20mutant%20female%20eye%20tissue%2C%20as%20in%20wild-type%20male%20eyes.%20A%20PCR%20survey%20of%20UVRh1%20sex-linkage%20across%20the%20genus%20shows%20that%20species%20with%20female-specific%20UVRh1%20expression%20lack%20UVRh1%20gDNA%20in%20males.%20Thus%2C%20acquisition%20of%20sex%20linkage%20is%20sufficient%20to%20achieve%20female-specific%20expression%20of%20UVRh1%2C%20though%20this%20does%20not%20preclude%20other%20mechanisms%2C%20like%20cis-regulatory%20evolution%20from%20also%20contributing.%20Moreover%2C%20both%20this%20event%2C%20and%20mutations%20leading%20to%20differential%20UV%20opsin%20sensitivity%2C%20occurred%20early%20in%20the%20history%20of%20Heliconius.%20These%20results%20suggest%20a%20path%20for%20acquiring%20sexual%20dimorphism%20distinct%20from%20existing%20mechanistic%20models.%20We%20propose%20a%20model%20where%20gene%20traffic%20to%20heterosomes%20%28the%20W%20or%20the%20Y%29%20genetically%20partitions%20a%20trait%20by%20sex%20before%20a%20phenotype%20shifts%20%28spectral%20tuning%20of%20UV%20sensitivity%29.%22%2C%22date%22%3A%222023-08-15%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1073%5C%2Fpnas.2301411120%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237552755%22%2C%22PMCID%22%3A%22PMC10438391%22%2C%22ISSN%22%3A%221091-6490%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%2257MMY8CK%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Moura%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMoura%2C%20P.%20A.%2C%20Young%2C%20F.%20J.%2C%20Monllor%2C%20M.%2C%20Cardoso%2C%20M.%20Z.%2C%20%26amp%3B%20Montgomery%2C%20S.%20H.%20%282023%29.%20Long-term%20spatial%20memory%20across%20large%20spatial%20scales%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BCurrent%20Biology%3A%20CB%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B33%26lt%3B%5C%2Fi%26gt%3B%2815%29%2C%20R797%26%23x2013%3BR798.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cub.2023.06.009%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cub.2023.06.009%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Long-term%20spatial%20memory%20across%20large%20spatial%20scales%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Priscila%20A.%22%2C%22lastName%22%3A%22Moura%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fletcher%20J.%22%2C%22lastName%22%3A%22Young%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Monica%22%2C%22lastName%22%3A%22Monllor%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcio%20Z.%22%2C%22lastName%22%3A%22Cardoso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%5D%2C%22abstractNote%22%3A%22Locating%20food%20in%20heterogeneous%20environments%20is%20a%20core%20survival%20challenge.%20The%20distribution%20of%20resources%20shapes%20foraging%20strategies%2C%20imposing%20demands%20on%20perception%2C%20learning%20and%20memory%2C%20and%20associated%20brain%20structures.%20Indeed%2C%20selection%20for%20foraging%20efficiency%20is%20linked%20to%20brain%20expansion%20in%20diverse%20taxa%2C%20from%20primates1%20to%20Hymenopterans2.%20Among%20butterflies%2C%20Heliconius%20have%20a%20unique%20dietary%20adaptation%2C%20actively%20collecting%20and%20feeding%20on%20pollen%2C%20providing%20a%20source%20of%20essential%20amino%20acids%20as%20adults%2C%20negating%20reproductive%20senescence%20and%20facilitating%20an%20extended%20longevity3.%20Several%20lines%20of%20evidence%20suggest%20that%20Heliconius%20learn%20the%20spatial%20location%20of%20pollen%20resources%20within%20an%20individual%26%23039%3Bs%20home%20range4%2C%20and%20spatial%20learning%20may%20be%20more%20pronounced%20at%20these%20large%20spatial%20scales.%20However%2C%20experimental%20evidence%20of%20spatial%20learning%20in%20Heliconius%2C%20or%20any%20other%20butterfly%2C%20is%20so%20far%20absent.%20We%20therefore%20tested%20the%20ability%20of%20Heliconius%20to%20learn%20the%20spatial%20location%20of%20food%20rewards%20at%20three%20ecologically-relevant%20spatial%20scales%2C%20representing%20multiple%20flowers%20on%20a%20single%20plant%2C%20multiple%20plants%20within%20a%20locality%2C%20and%20multiple%20localities.%20Heliconius%20were%20able%20to%20learn%20spatial%20information%20at%20all%20three%20scales%2C%20consistent%20with%20this%20ability%20being%20an%20important%20component%20of%20their%20natural%20foraging%20behaviour.%22%2C%22date%22%3A%222023-08-07%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.cub.2023.06.009%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237552941%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221879-0445%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%229TL8V6I4%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Thawornwattana%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BThawornwattana%2C%20Y.%2C%20Huang%2C%20J.%2C%20Flouri%2C%20T.%2C%20Mallet%2C%20J.%2C%20%26amp%3B%20Yang%2C%20Z.%20%282023%29.%20Inferring%20the%20Direction%20of%20Introgression%20Using%20Genomic%20Sequence%20Data.%20%26lt%3Bi%26gt%3BMolecular%20Biology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B40%26lt%3B%5C%2Fi%26gt%3B%288%29%2C%20msad178.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsad178%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsad178%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Inferring%20the%20Direction%20of%20Introgression%20Using%20Genomic%20Sequence%20Data%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yuttapong%22%2C%22lastName%22%3A%22Thawornwattana%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jun%22%2C%22lastName%22%3A%22Huang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tom%5Cu00e1%5Cu0161%22%2C%22lastName%22%3A%22Flouri%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%22%2C%22lastName%22%3A%22Mallet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ziheng%22%2C%22lastName%22%3A%22Yang%22%7D%5D%2C%22abstractNote%22%3A%22Genomic%20data%20are%20informative%20about%20the%20history%20of%20species%20divergence%20and%20interspecific%20gene%20flow%2C%20including%20the%20direction%2C%20timing%2C%20and%20strength%20of%20gene%20flow.%20However%2C%20gene%20flow%20in%20opposite%20directions%20generates%20similar%20patterns%20in%20multilocus%20sequence%20data%2C%20such%20as%20reduced%20sequence%20divergence%20between%20the%20hybridizing%20species.%20As%20a%20result%2C%20inference%20of%20the%20direction%20of%20gene%20flow%20is%20challenging.%20Here%2C%20we%20investigate%20the%20information%20about%20the%20direction%20of%20gene%20flow%20present%20in%20genomic%20sequence%20data%20using%20likelihood-based%20methods%20under%20the%20multispecies-coalescent-with-introgression%20model.%20We%20analyze%20the%20case%20of%20two%20species%2C%20and%20use%20simulation%20to%20examine%20cases%20with%20three%20or%20four%20species.%20We%20find%20that%20it%20is%20easier%20to%20infer%20gene%20flow%20from%20a%20small%20population%20to%20a%20large%20one%20than%20in%20the%20opposite%20direction%2C%20and%20easier%20to%20infer%20inflow%20%28gene%20flow%20from%20outgroup%20species%20to%20an%20ingroup%20species%29%20than%20outflow%20%28gene%20flow%20from%20an%20ingroup%20species%20to%20an%20outgroup%20species%29.%20It%20is%20also%20easier%20to%20infer%20gene%20flow%20if%20there%20is%20a%20longer%20time%20of%20separate%20evolution%20between%20the%20initial%20divergence%20and%20subsequent%20introgression.%20When%20introgression%20is%20assumed%20to%20occur%20in%20the%20wrong%20direction%2C%20the%20time%20of%20introgression%20tends%20to%20be%20correctly%20estimated%20and%20the%20Bayesian%20test%20of%20gene%20flow%20is%20often%20significant%2C%20while%20estimates%20of%20introgression%20probability%20can%20be%20even%20greater%20than%20the%20true%20probability.%20We%20analyze%20genomic%20sequences%20from%20Heliconius%20butterflies%20to%20demonstrate%20that%20typical%20genomic%20datasets%20are%20informative%20about%20the%20direction%20of%20interspecific%20gene%20flow%2C%20as%20well%20as%20its%20timing%20and%20strength.%22%2C%22date%22%3A%222023-08-03%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fmolbev%5C%2Fmsad178%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237552932%22%2C%22PMCID%22%3A%22PMC10439365%22%2C%22ISSN%22%3A%221537-1719%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22LYHFZKRP%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Hebberecht%20et%20al.%22%2C%22parsedDate%22%3A%222023-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHebberecht%2C%20L.%2C%20Wainwright%2C%20J.%20B.%2C%20Thompson%2C%20C.%2C%20Kershenbaum%2C%20S.%2C%20McMillan%2C%20W.%20O.%2C%20%26amp%3B%20Montgomery%2C%20S.%20H.%20%282023%29.%20Plasticity%20and%20genetic%20effects%20contribute%20to%20different%20axes%20of%20neural%20divergence%20in%20a%20community%20of%20mimetic%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BJournal%20of%20Evolutionary%20Biology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B36%26lt%3B%5C%2Fi%26gt%3B%288%29%2C%201116%26%23x2013%3B1132.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjeb.14188%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjeb.14188%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Plasticity%20and%20genetic%20effects%20contribute%20to%20different%20axes%20of%20neural%20divergence%20in%20a%20community%20of%20mimetic%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Hebberecht%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20Benito%22%2C%22lastName%22%3A%22Wainwright%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Thompson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simon%22%2C%22lastName%22%3A%22Kershenbaum%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%5D%2C%22abstractNote%22%3A%22Changes%20in%20ecological%20preference%2C%20often%20driven%20by%20spatial%20and%20temporal%20variation%20in%20resource%20distribution%2C%20can%20expose%20populations%20to%20environments%20with%20divergent%20information%20content.%20This%20can%20lead%20to%20adaptive%20changes%20in%20the%20degree%20to%20which%20individuals%20invest%20in%20sensory%20systems%20and%20downstream%20processes%2C%20to%20optimize%20behavioural%20performance%20in%20different%20contexts.%20At%20the%20same%20time%2C%20environmental%20conditions%20can%20produce%20plastic%20responses%20in%20nervous%20system%20development%20and%20maturation%2C%20providing%20an%20alternative%20route%20to%20integrating%20neural%20and%20ecological%20variation.%20Here%2C%20we%20explore%20how%20these%20two%20processes%20play%20out%20across%20a%20community%20of%20Heliconius%20butterflies.%20Heliconius%20communities%20exhibit%20multiple%20Mullerian%20mimicry%20rings%2C%20associated%20with%20habitat%20partitioning%20across%20environmental%20gradients.%20These%20environmental%20differences%20have%20previously%20been%20linked%20to%20heritable%20divergence%20in%20brain%20morphology%20in%20parapatric%20species%20pairs.%20They%20also%20exhibit%20a%20unique%20dietary%20adaptation%2C%20known%20as%20pollen%20feeding%2C%20that%20relies%20heavily%20on%20learning%20foraging%20routes%2C%20or%20trap-lines%2C%20between%20resources%2C%20which%20implies%20an%20important%20environmental%20influence%20on%20behavioural%20development.%20By%20comparing%20brain%20morphology%20across%20133%20wild-caught%20and%20insectary-reared%20individuals%20from%20seven%20Heliconius%20species%2C%20we%20find%20strong%20evidence%20for%20interspecific%20variation%20in%20patterns%20of%20neural%20investment.%20These%20largely%20fall%20into%20two%20distinct%20patterns%20of%20variation%3B%20first%2C%20we%20find%20consistent%20patterns%20of%20divergence%20in%20the%20size%20of%20visual%20brain%20components%20across%20both%20wild%20and%20insectary-reared%20individuals%2C%20suggesting%20genetically%20encoded%20divergence%20in%20the%20visual%20pathway.%20Second%2C%20we%20find%20interspecific%20differences%20in%20mushroom%20body%20size%2C%20a%20central%20component%20of%20learning%20and%20memory%20systems%2C%20but%20only%20among%20wild%20caught%20individuals.%20The%20lack%20of%20this%20effect%20in%20common-garden%20individuals%20suggests%20an%20extensive%20role%20for%20developmental%20plasticity%20in%20interspecific%20variation%20in%20the%20wild.%20Finally%2C%20we%20illustrate%20the%20impact%20of%20relatively%20small-scale%20spatial%20effects%20on%20mushroom%20body%20plasticity%20by%20performing%20experiments%20altering%20the%20cage%20size%20and%20structure%20experienced%20by%20individual%20H.%5Cu2009hecale.%20Our%20data%20provide%20a%20comprehensive%20survey%20of%20community%20level%20variation%20in%20brain%20structure%2C%20and%20demonstrate%20that%20genetic%20effects%20and%20developmental%20plasticity%20contribute%20to%20different%20axes%20of%20interspecific%20neural%20variation.%22%2C%22date%22%3A%222023-08%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2Fjeb.14188%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237341138%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221420-9101%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22ASRFMU9G%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Young%20et%20al.%22%2C%22parsedDate%22%3A%222023-07-26%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BYoung%2C%20F.%20J.%2C%20Monllor%2C%20M.%2C%20McMillan%2C%20W.%20O.%2C%20%26amp%3B%20Montgomery%2C%20S.%20H.%20%282023%29.%20Patterns%20of%20host%20plant%20use%20do%20not%20explain%20mushroom%20body%20expansion%20in%20Heliconiini%20butterflies.%20%26lt%3Bi%26gt%3BProceedings.%20Biological%20Sciences%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B290%26lt%3B%5C%2Fi%26gt%3B%282003%29%2C%2020231155.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frspb.2023.1155%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frspb.2023.1155%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Patterns%20of%20host%20plant%20use%20do%20not%20explain%20mushroom%20body%20expansion%20in%20Heliconiini%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fletcher%20J.%22%2C%22lastName%22%3A%22Young%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Monica%22%2C%22lastName%22%3A%22Monllor%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%5D%2C%22abstractNote%22%3A%22The%20selective%20pressures%20leading%20to%20the%20elaboration%20of%20downstream%2C%20integrative%20processing%20centres%2C%20such%20as%20the%20mammalian%20neocortex%20or%20insect%20mushroom%20bodies%2C%20are%20often%20unclear.%20In%20Heliconius%20butterflies%2C%20the%20mushroom%20bodies%20are%20two%20to%20four%20times%20larger%20than%20those%20of%20their%20Heliconiini%20relatives%2C%20and%20the%20largest%20known%20in%20Lepidoptera.%20Heliconiini%20lay%20almost%20exclusively%20on%20Passiflora%2C%20which%20exhibit%20a%20remarkable%20diversity%20of%20leaf%20shape%2C%20and%20it%20has%20been%20suggested%20that%20the%20mushroom%20body%20expansion%20of%20Heliconius%20may%20have%20been%20driven%20by%20the%20cognitive%20demands%20of%20recognizing%20and%20learning%20leaf%20shapes%20of%20local%20host%20plants.%20We%20test%20this%20hypothesis%20using%20two%20complementary%20methods%3A%20%28i%29%20phylogenetic%20comparative%20analyses%20to%20test%20whether%20variation%20in%20mushroom%20body%20size%20is%20associated%20with%20the%20morphological%20diversity%20of%20host%20plants%20exploited%20across%20the%20Heliconiini%3B%20and%20%28ii%29%20shape-learning%20experiments%20using%20six%20Heliconiini%20species.%20We%20found%20that%20variation%20in%20the%20range%20of%20leaf%20morphologies%20used%20by%20Heliconiini%20was%20not%20associated%20with%20mushroom%20body%20volume.%20Similarly%2C%20we%20find%20interspecific%20differences%20in%20shape-learning%20ability%2C%20but%20Heliconius%20are%20not%20overall%20better%20shape%20learners%20than%20other%20Heliconiini.%20Together%20these%20results%20suggest%20that%20the%20visual%20recognition%20and%20learning%20of%20host%20plants%20was%20not%20a%20main%20factor%20driving%20the%20diversity%20of%20mushroom%20body%20size%20in%20this%20tribe.%22%2C%22date%22%3A%222023-07-26%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1098%5C%2Frspb.2023.1155%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237491961%22%2C%22PMCID%22%3A%22PMC10369028%22%2C%22ISSN%22%3A%221471-2954%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22K2QF9AWZ%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Guichard%20et%20al.%22%2C%22parsedDate%22%3A%222023-07-14%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BGuichard%2C%20A.%2C%20Legeai%2C%20F.%2C%20Tagu%2C%20D.%2C%20%26amp%3B%20Lemaitre%2C%20C.%20%282023%29.%20MTG-Link%3A%20leveraging%20barcode%20information%20from%20linked-reads%20to%20assemble%20specific%20loci.%20%26lt%3Bi%26gt%3BBMC%20Bioinformatics%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B24%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20284.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12859-023-05395-w%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12859-023-05395-w%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22MTG-Link%3A%20leveraging%20barcode%20information%20from%20linked-reads%20to%20assemble%20specific%20loci%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Guichard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabrice%22%2C%22lastName%22%3A%22Legeai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Denis%22%2C%22lastName%22%3A%22Tagu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claire%22%2C%22lastName%22%3A%22Lemaitre%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Local%20assembly%20with%20short%20and%20long%20reads%20has%20proven%20to%20be%20very%20useful%20in%20many%20applications%3A%20reconstruction%20of%20the%20sequence%20of%20a%20locus%20of%20interest%2C%20gap-filling%20in%20draft%20assemblies%2C%20as%20well%20as%20alternative%20allele%20reconstruction%20of%20large%20Structural%20Variants.%20Whereas%20linked-read%20technologies%20have%20a%20great%20potential%20to%20assemble%20specific%20loci%20as%20they%20provide%20long-range%20information%20while%20maintaining%20the%20power%20and%20accuracy%20of%20short-read%20sequencing%2C%20there%20is%20a%20lack%20of%20local%20assembly%20tools%20for%20linked-read%20data.%5CnRESULTS%3A%20We%20present%20MTG-Link%2C%20a%20novel%20local%20assembly%20tool%20dedicated%20to%20linked-reads.%20The%20originality%20of%20the%20method%20lies%20in%20its%20read%20subsampling%20step%20which%20takes%20advantage%20of%20the%20barcode%20information%20contained%20in%20linked-reads%20mapped%20in%20flanking%20regions.%20We%20validated%20our%20approach%20on%20several%20datasets%20from%20different%20linked-read%20technologies.%20We%20show%20that%20MTG-Link%20is%20able%20to%20assemble%20successfully%20large%20sequences%2C%20up%20to%20dozens%20of%20Kb.%20We%20also%20demonstrate%20that%20the%20read%20subsampling%20step%20of%20MTG-Link%20considerably%20improves%20the%20local%20assembly%20of%20specific%20loci%20compared%20to%20other%20existing%20short-read%20local%20assembly%20tools.%20Furthermore%2C%20MTG-Link%20was%20able%20to%20fully%20characterize%20large%20insertion%20variants%20and%20deletion%20breakpoints%20in%20a%20human%20genome%20and%20to%20reconstruct%20dark%20regions%20in%20clinically-relevant%20human%20genes.%20It%20also%20improved%20the%20contiguity%20of%20a%201.3%5Cu00a0Mb%20locus%20of%20biological%20interest%20in%20several%20individual%20genomes%20of%20the%20mimetic%20butterfly%20Heliconius%20numata.%5CnCONCLUSIONS%3A%20MTG-Link%20is%20an%20efficient%20local%20assembly%20tool%20designed%20for%20different%20linked-read%20sequencing%20technologies.%20MTG-Link%20source%20code%20is%20available%20at%20https%3A%5C%2F%5C%2Fgithub.com%5C%2Fanne-gcd%5C%2FMTG-Link%20and%20as%20a%20Bioconda%20package.%22%2C%22date%22%3A%222023-07-14%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12859-023-05395-w%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237452278%22%2C%22PMCID%22%3A%22PMC10347852%22%2C%22ISSN%22%3A%221471-2105%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22ZT8PP87D%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Couto%20et%20al.%22%2C%22parsedDate%22%3A%222023-07-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCouto%2C%20A.%2C%20Young%2C%20F.%20J.%2C%20Atzeni%2C%20D.%2C%20Marty%2C%20S.%2C%20Melo-Fl%26%23xF3%3Brez%2C%20L.%2C%20Hebberecht%2C%20L.%2C%20Monllor%2C%20M.%2C%20Neal%2C%20C.%2C%20Cicconardi%2C%20F.%2C%20McMillan%2C%20W.%20O.%2C%20%26amp%3B%20Montgomery%2C%20S.%20H.%20%282023%29.%20Rapid%20expansion%20and%20visual%20specialisation%20of%20learning%20and%20memory%20centres%20in%20the%20brains%20of%20Heliconiini%20butterflies.%20%26lt%3Bi%26gt%3BNature%20Communications%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B14%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%204024.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-023-39618-8%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-023-39618-8%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Rapid%20expansion%20and%20visual%20specialisation%20of%20learning%20and%20memory%20centres%20in%20the%20brains%20of%20Heliconiini%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antoine%22%2C%22lastName%22%3A%22Couto%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fletcher%20J.%22%2C%22lastName%22%3A%22Young%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniele%22%2C%22lastName%22%3A%22Atzeni%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simon%22%2C%22lastName%22%3A%22Marty%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lina%22%2C%22lastName%22%3A%22Melo-Fl%5Cu00f3rez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Hebberecht%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Monica%22%2C%22lastName%22%3A%22Monllor%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%22%2C%22lastName%22%3A%22Neal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francesco%22%2C%22lastName%22%3A%22Cicconardi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%5D%2C%22abstractNote%22%3A%22Changes%20in%20the%20abundance%20and%20diversity%20of%20neural%20cell%20types%2C%20and%20their%20connectivity%2C%20shape%20brain%20composition%20and%20provide%20the%20substrate%20for%20behavioral%20evolution.%20Although%20investment%20in%20sensory%20brain%20regions%20is%20understood%20to%20be%20largely%20driven%20by%20the%20relative%20ecological%20importance%20of%20particular%20sensory%20modalities%2C%20how%20selective%20pressures%20impact%20the%20elaboration%20of%20integrative%20brain%20centers%20has%20been%20more%20difficult%20to%20pinpoint.%20Here%2C%20we%20provide%20evidence%20of%20extensive%2C%20mosaic%20expansion%20of%20an%20integration%20brain%20center%20among%20closely%20related%20species%2C%20which%20is%20not%20explained%20by%20changes%20in%20sites%20of%20primary%20sensory%20input.%20By%20building%20new%20datasets%20of%20neural%20traits%20among%20a%20tribe%20of%20diverse%20Neotropical%20butterflies%2C%20the%20Heliconiini%2C%20we%20detected%20several%20major%20evolutionary%20expansions%20of%20the%20mushroom%20bodies%2C%20central%20brain%20structures%20pivotal%20for%20insect%20learning%20and%20memory.%20The%20genus%20Heliconius%2C%20which%20exhibits%20a%20unique%20dietary%20innovation%2C%20pollen-feeding%2C%20and%20derived%20foraging%20behaviors%20reliant%20on%20spatial%20memory%2C%20shows%20the%20most%20extreme%20enlargement.%20This%20expansion%20is%20primarily%20associated%20with%20increased%20visual%20processing%20areas%20and%20coincides%20with%20increased%20precision%20of%20visual%20processing%2C%20and%20enhanced%20long%20term%20memory.%20These%20results%20demonstrate%20that%20selection%20for%20behavioral%20innovation%20and%20enhanced%20cognitive%20ability%20occurred%20through%20expansion%20and%20localized%20specialization%20in%20integrative%20brain%20centers.%22%2C%22date%22%3A%222023-07-07%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-023-39618-8%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237419890%22%2C%22PMCID%22%3A%22PMC10328955%22%2C%22ISSN%22%3A%222041-1723%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22N78LR9GS%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Rougemont%20et%20al.%22%2C%22parsedDate%22%3A%222023-07-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BRougemont%2C%20Q.%2C%20Huber%2C%20B.%2C%20Martin%2C%20S.%20H.%2C%20Whibley%2C%20A.%2C%20Estrada%2C%20C.%2C%20Solano%2C%20D.%2C%20Orpet%2C%20R.%2C%20McMillan%2C%20W.%20O.%2C%20Fr%26%23xE9%3Brot%2C%20B.%2C%20%26amp%3B%20Joron%2C%20M.%20%282023%29.%20Subtle%20Introgression%20Footprints%20at%20the%20End%20of%20the%20Speciation%20Continuum%20in%20a%20Clade%20of%20Heliconius%20Butterflies.%20%26lt%3Bi%26gt%3BMolecular%20Biology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B40%26lt%3B%5C%2Fi%26gt%3B%287%29%2C%20msad166.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsad166%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsad166%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Subtle%20Introgression%20Footprints%20at%20the%20End%20of%20the%20Speciation%20Continuum%20in%20a%20Clade%20of%20Heliconius%20Butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Quentin%22%2C%22lastName%22%3A%22Rougemont%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B%5Cu00e1rbara%22%2C%22lastName%22%3A%22Huber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simon%20H.%22%2C%22lastName%22%3A%22Martin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annabel%22%2C%22lastName%22%3A%22Whibley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Catalina%22%2C%22lastName%22%3A%22Estrada%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Darha%22%2C%22lastName%22%3A%22Solano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Orpet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Brigitte%22%2C%22lastName%22%3A%22Fr%5Cu00e9rot%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mathieu%22%2C%22lastName%22%3A%22Joron%22%7D%5D%2C%22abstractNote%22%3A%22Quantifying%20gene%20flow%20between%20lineages%20at%20different%20stages%20of%20the%20speciation%20continuum%20is%20central%20to%20understanding%20speciation.%20Heliconius%20butterflies%20have%20undergone%20an%20adaptive%20radiation%20in%20wing%20color%20patterns%20driven%20partly%20by%20natural%20selection%20for%20local%20mimicry.%20Color%20patterns%20are%20also%20known%20to%20be%20used%20as%20assortative%20mating%20cues.%20Therefore%2C%20wing%20pattern%20divergence%20is%20considered%20to%20play%20a%20role%20in%20speciation.%20A%20corollary%20is%20that%20mimicry%20between%20closely%20related%20species%20may%20be%20associated%20with%20hybridization%20and%20interfere%20with%20reproductive%20isolation.%20Here%2C%20we%20take%20a%20multifaceted%20approach%20to%20explore%20speciation%20history%2C%20species%20boundaries%2C%20and%20traits%20involved%20in%20species%20differentiation%20between%20the%20two%20closely%20related%20species%2C%20Heliconius%20hecale%20and%20Heliconius%20ismenius.%20We%20focus%20on%20geographic%20regions%20where%20the%20two%20species%20mimic%20each%20other%20and%20contrast%20this%20with%20geographic%20regions%20where%20they%20do%20not%20mimic%20each%20other.%20To%20examine%20population%20history%20and%20patterns%20of%20gene%20flow%2C%20we%20tested%20and%20compared%20a%20four-population%20model%20accounting%20for%20linked%20selection.%20This%20model%20suggests%20that%20the%20two%20species%20have%20remained%20isolated%20for%20a%20large%20part%20of%20their%20history%2C%20yet%20with%20a%20small%20amount%20of%20gene%20exchange.%20Accordingly%2C%20signatures%20of%20genomic%20introgression%20were%20small%20except%20at%20a%20major%20wing%20pattern%20allele%20and%20chemosensing%20genes%20and%20stronger%20in%20the%20mimetic%20populations%20compared%20with%20nonmimetic%20populations.%20Behavioral%20assays%20confirm%20that%20visual%20confusion%20exists%20but%20that%20short-range%20cues%20determine%20strong%20sexual%20isolation.%20Tests%20for%20chemical%20differentiation%20between%20species%20identified%20major%20differences%20in%20putative%20pheromones%20which%20likely%20mediate%20mate%20choice%20and%20the%20maintenance%20of%20species%20differences.%22%2C%22date%22%3A%222023-07-05%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fmolbev%5C%2Fmsad166%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237467472%22%2C%22PMCID%22%3A%22PMC10375063%22%2C%22ISSN%22%3A%221537-1719%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22CEPJBWQV%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Borrero%20et%20al.%22%2C%22parsedDate%22%3A%222023-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBorrero%2C%20J.%2C%20Wright%2C%20D.%20S.%2C%20Bacquet%2C%20C.%20N.%2C%20%26amp%3B%20Merrill%2C%20R.%20M.%20%282023%29.%20Oviposition%20behavior%20is%20not%20affected%20by%20ultraviolet%20light%20in%20a%20butterfly%20with%20sexually-dimorphic%20expression%20of%20a%20UV-sensitive%20opsin.%20%26lt%3Bi%26gt%3BEcology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B13%26lt%3B%5C%2Fi%26gt%3B%287%29%2C%20e10243.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.10243%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.10243%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Oviposition%20behavior%20is%20not%20affected%20by%20ultraviolet%20light%20in%20a%20butterfly%20with%20sexually-dimorphic%20expression%20of%20a%20UV-sensitive%20opsin%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jose%22%2C%22lastName%22%3A%22Borrero%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%20Shane%22%2C%22lastName%22%3A%22Wright%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%20Nicole%22%2C%22lastName%22%3A%22Bacquet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richard%20M.%22%2C%22lastName%22%3A%22Merrill%22%7D%5D%2C%22abstractNote%22%3A%22Animal%20vision%20is%20important%20for%20mediating%20multiple%20complex%20behaviors.%20In%20Heliconius%20butterflies%2C%20vision%20guides%20fundamental%20behaviors%20such%20as%20oviposition%2C%20foraging%2C%20and%20mate%20choice.%20Color%20vision%20in%20Heliconius%20involves%20ultraviolet%20%28UV%29%2C%20blue%20and%20long-wavelength-sensitive%20photoreceptors%20%28opsins%29.%20Additionally%2C%20Heliconius%20possess%20a%20duplicated%20UV%20opsin%2C%20and%20its%20expression%20varies%20widely%20within%20the%20genus.%20In%20Heliconius%20erato%2C%20opsin%20expression%20is%20sexually%20dimorphic%3B%20only%20females%20express%20both%20UV-sensitive%20opsins%2C%20enabling%20UV%20wavelength%20discrimination.%20However%2C%20the%20selective%20pressures%20responsible%20for%20sex-specific%20differences%20in%20opsin%20expression%20and%20visual%20perception%20remain%20unresolved.%20Female%20Heliconius%20invest%20heavily%20in%20finding%20suitable%20hostplants%20for%20oviposition%2C%20a%20behavior%20heavily%20dependent%20on%20visual%20cues.%20Here%2C%20we%20tested%20the%20hypothesis%20that%20UV%20vision%20is%20important%20for%20oviposition%20in%20H.%20erato%20and%20Heliconius%20himera%20females%20by%20manipulating%20the%20availability%20of%20UV%20in%20behavioral%20experiments%20under%20natural%20conditions.%20Our%20results%20indicate%20that%20UV%20does%20not%20influence%20the%20number%20of%20oviposition%20attempts%20or%20eggs%20laid%2C%20and%20the%20hostplant%2C%20Passiflora%20punctata%2C%20does%20not%20reflect%20UV%20wavelengths.%20Models%20of%20H.%20erato%20female%20vision%20suggest%20only%20minimal%20stimulation%20of%20the%20UV%20opsins.%20Overall%2C%20these%20findings%20suggest%20that%20UV%20wavelengths%20do%20not%20directly%20affect%20the%20ability%20of%20Heliconius%20females%20to%20find%20suitable%20oviposition%20sites.%20Alternatively%2C%20UV%20discrimination%20could%20be%20used%20in%20the%20context%20of%20foraging%20or%20mate%20choice%2C%20but%20this%20remains%20to%20be%20tested.%22%2C%22date%22%3A%222023-07%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fece3.10243%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237408633%22%2C%22PMCID%22%3A%22PMC10318619%22%2C%22ISSN%22%3A%222045-7758%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%228ZEI5QYQ%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Rivas-S%5Cu00e1nchez%20et%20al.%22%2C%22parsedDate%22%3A%222023-06-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BRivas-S%26%23xE1%3Bnchez%2C%20D.%20F.%2C%20Melo-Fl%26%23xF3%3Brez%2C%20L.%2C%20Arag%26%23xF3%3Bn%2C%20A.%2C%20Pardo-D%26%23xED%3Baz%2C%20C.%2C%20Salazar%2C%20C.%2C%20Montgomery%2C%20S.%20H.%2C%20%26amp%3B%20Merrill%2C%20R.%20M.%20%282023%29.%20Parallel%20evolution%20of%20behavior%2C%20physiology%2C%20and%20life%20history%20associated%20with%20altitudinal%20shifts%20in%20forest%20type%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BEvolution%3B%20International%20Journal%20of%20Organic%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B77%26lt%3B%5C%2Fi%26gt%3B%286%29%2C%201458%26%23x2013%3B1467.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fevolut%5C%2Fqpad062%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fevolut%5C%2Fqpad062%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Parallel%20evolution%20of%20behavior%2C%20physiology%2C%20and%20life%20history%20associated%20with%20altitudinal%20shifts%20in%20forest%20type%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%20F.%22%2C%22lastName%22%3A%22Rivas-S%5Cu00e1nchez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lina%22%2C%22lastName%22%3A%22Melo-Fl%5Cu00f3rez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrea%22%2C%22lastName%22%3A%22Arag%5Cu00f3n%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolina%22%2C%22lastName%22%3A%22Pardo-D%5Cu00edaz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camilo%22%2C%22lastName%22%3A%22Salazar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richard%20M.%22%2C%22lastName%22%3A%22Merrill%22%7D%5D%2C%22abstractNote%22%3A%22Parallel%20evolution%20of%20morphological%20traits%20is%20widely%20reported%2C%20providing%20evidence%20for%20the%20role%20of%20local%20conditions%20in%20driving%20adaptive%20divergence.%20Comparatively%2C%20fewer%20studies%20have%20tested%20for%20parallelism%20in%20behavior%2C%20and%20it%20is%20less%20clear%20to%20what%20extent%20heritable%20behavioral%20shifts%20contribute%20to%20adaptive%20divergence.%20We%20exploit%20repeated%20incipient%20speciation%20across%20altitudinal%20gradients%20to%20explore%20behavior%20and%20physiology%20in%20Heliconius%20butterflies%20adapted%20to%20high-elevation.%20We%20performed%20common%20garden%20experiments%20with%20H.%20chestertonii%2C%20a%20high-altitude%20specialist%20from%20the%20Colombian%20Cordillera%20Occidental%2C%20and%20H.%20erato%20venus%2C%20a%20low-elevation%20proxy%20for%20the%20ancestral%20population%2C%20and%20compared%20our%20results%20to%20existing%20data%20for%20an%20equivalent%20Ecuadorian%20taxa-pair.%20Using%20broad-scale%20climatic%20data%2C%20we%20show%20that%20both%20pairs%20diverge%20across%20similar%20ecological%20gradients%2C%20confirmed%20using%20localized%20data%20loggers%20in%20the%20ranges%20of%20H.%20chestertonii%20and%20H.%20e.%20venus.%20We%20further%20show%20that%20H.%20chestertonii%20and%20H.%20e.%20venus%20have%20divergent%20activity%20patterns%2C%20attributable%20to%20different%20responses%20to%20microclimate%2C%20and%20life%20histories.%20Finally%2C%20we%20provide%20evidence%20for%20parallelism%20in%20these%20traits%20with%20H.%20himera%20and%20H.%20e.%20cyrbia.%20We%20propose%20that%20this%20is%20a%20result%20of%20selection%20associated%20with%20independent%20colonizations%20of%20high-altitude%20forests%2C%20emphasizing%20the%20importance%20of%20heritable%20behavioral%20and%20physiological%20adaptations%20during%20population%20divergence%20and%20speciation.%22%2C%22date%22%3A%222023-06-01%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fevolut%5C%2Fqpad062%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237075171%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221558-5646%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22JJ4SXAKY%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Zhang%20et%20al.%22%2C%22parsedDate%22%3A%222023-05-31%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BZhang%2C%20Y.%2C%20Zhu%2C%20Q.%2C%20Shao%2C%20Y.%2C%20Jiang%2C%20Y.%2C%20Ouyang%2C%20Y.%2C%20Zhang%2C%20L.%2C%20%26amp%3B%20Zhang%2C%20W.%20%282023%29.%20Inferring%20historical%20introgression%20with%20deep%20learning.%20%26lt%3Bi%26gt%3BSystematic%20Biology%26lt%3B%5C%2Fi%26gt%3B%2C%20syad033.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyad033%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyad033%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Inferring%20historical%20introgression%20with%20deep%20learning%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yubo%22%2C%22lastName%22%3A%22Zhang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qingjie%22%2C%22lastName%22%3A%22Zhu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yi%22%2C%22lastName%22%3A%22Shao%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yanchen%22%2C%22lastName%22%3A%22Jiang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yidan%22%2C%22lastName%22%3A%22Ouyang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Li%22%2C%22lastName%22%3A%22Zhang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wei%22%2C%22lastName%22%3A%22Zhang%22%7D%5D%2C%22abstractNote%22%3A%22Resolving%20phylogenetic%20relationships%20among%20taxa%20remains%20a%20challenge%20in%20the%20era%20of%20big%20data%20due%20to%20the%20presence%20of%20genetic%20admixture%20in%20a%20wide%20range%20of%20organisms.%20Rapidly%20developing%20sequencing%20technologies%20and%20statistical%20tests%20enable%20evolutionary%20relationships%20to%20be%20disentangled%20at%20a%20genome-wide%20level%2C%20yet%20many%20of%20these%20tests%20are%20computationally%20intensive%20and%20rely%20on%20phased%20genotypes%2C%20large%20sample%20sizes%2C%20restricted%20phylogenetic%20topologies%2C%20or%20hypothesis%20testing.%20To%20overcome%20these%20difficulties%2C%20we%20developed%20a%20deep%20learning-based%20approach%2C%20named%20ERICA%2C%20for%20inferring%20genome-wide%20evolutionary%20relationships%20and%20local%20introgressed%20regions%20from%20sequence%20data.%20ERICA%20accepts%20sequence%20alignments%20of%20both%20population%20genomic%20data%20and%20multiple%20genome%20assemblies%2C%20and%20efficiently%20identifies%20discordant%20genealogy%20patterns%20and%20exchanged%20regions%20across%20genomes%20when%20compared%20with%20other%20methods.%20We%20further%20tested%20ERICA%20using%20real%20population%20genomic%20data%20from%20Heliconius%20butterflies%20that%20have%20undergone%20adaptive%20radiation%20and%20frequent%20hybridization.%20Finally%2C%20we%20applied%20ERICA%20to%20characterize%20hybridization%20and%20introgression%20in%20wild%20and%20cultivated%20rice%2C%20revealing%20the%20important%20role%20of%20introgression%20in%20rice%20domestication%20and%20adaptation.%20Taken%20together%2C%20our%20findings%20demonstrate%20that%20ERICA%20provides%20an%20effective%20method%20for%20teasing%20apart%20evolutionary%20relationships%20using%20whole%20genome%20data%2C%20which%20can%20ultimately%20facilitate%20evolutionary%20studies%20on%20hybridization%20and%20introgression.%22%2C%22date%22%3A%222023-05-31%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fsysbio%5C%2Fsyad033%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237257491%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221076-836X%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22MNVUL2XB%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Bayala%20et%20al.%22%2C%22parsedDate%22%3A%222023-05-11%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBayala%2C%20E.%20X.%2C%20Cisneros%2C%20I.%2C%20Massardo%2C%20D.%2C%20VanKuren%2C%20N.%20W.%2C%20%26amp%3B%20Kronforst%2C%20M.%20R.%20%282023%29.%20Divergent%20expression%20of%20aristaless1%20and%20aristaless2%20during%20embryonic%20appendage%20and%20pupal%20wing%20development%20in%20butterflies.%20%26lt%3Bi%26gt%3BBMC%20Biology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B21%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20104.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12915-023-01602-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12915-023-01602-5%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Divergent%20expression%20of%20aristaless1%20and%20aristaless2%20during%20embryonic%20appendage%20and%20pupal%20wing%20development%20in%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erick%20X.%22%2C%22lastName%22%3A%22Bayala%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabella%22%2C%22lastName%22%3A%22Cisneros%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Darli%22%2C%22lastName%22%3A%22Massardo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicholas%20W.%22%2C%22lastName%22%3A%22VanKuren%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcus%20R.%22%2C%22lastName%22%3A%22Kronforst%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Gene%20duplication%20events%20are%20critical%20for%20the%20evolution%20of%20new%20gene%20functions.%20Aristaless%20is%20a%20major%20regulator%20of%20distinct%20developmental%20processes.%20It%20is%20most%20known%20for%20its%20role%20during%20appendage%20development%20across%20animals.%20However%2C%20more%20recently%20other%20distinct%20biological%20functions%20have%20been%20described%20for%20this%20gene%20and%20its%20duplicates.%20Butterflies%20and%20moths%20have%20two%20copies%20of%20aristaless%2C%20aristaless1%20%28al1%29%20and%20aristaless2%20%28al2%29%2C%20as%20a%20result%20of%20a%20gene%20duplication%20event.%20Previous%20work%20in%20Heliconius%20has%20shown%20that%20both%20copies%20appear%20to%20have%20novel%20functions%20related%20to%20wing%20color%20patterning.%20Here%20we%20expand%20our%20knowledge%20of%20the%20expression%20profiles%20associated%20with%20both%20ancestral%20and%20novel%20functions%20of%20Al1%20across%20embryogenesis%20and%20wing%20pigmentation.%20Furthermore%2C%20we%20characterize%20Al2%20expression%2C%20providing%20a%20comparative%20framework%20between%20gene%20copies%20within%20the%20same%20species%2C%20allowing%20us%20to%20understand%20the%20origin%20of%20new%20functions%20following%20gene%20duplication.%5CnRESULTS%3A%20Our%20work%20shows%20that%20the%20expression%20of%20both%20Al1%20and%20Al2%20is%20associated%20with%20the%20ancestral%20function%20of%20sensory%20appendage%20%28leg%2C%20mouth%2C%20spines%2C%20and%20eyes%29%20development%20in%20embryos.%20Interestingly%2C%20Al1%20exhibits%20higher%20expression%20earlier%20in%20embryogenesis%20while%20the%20highest%20levels%20of%20Al2%20expression%20are%20shifted%20to%20later%20stages%20of%20embryonic%20development.%20Furthermore%2C%20Al1%20localization%20appears%20extranuclear%20while%20Al2%20co-localizes%20tightly%20with%20nuclei%20earlier%2C%20and%20then%20also%20expands%20outside%20the%20nucleus%20later%20in%20development.%20Cellular%20expression%20of%20Al1%20and%20Al2%20in%20pupal%20wings%20is%20broadly%20consistent%20with%20patterns%20observed%20during%20embryogenesis.%20We%20also%20describe%2C%20for%20the%20first%20time%2C%20how%20Al1%20localization%20appears%20to%20correlate%20with%20zones%20of%20anterior%5C%2Fposterior%20elongation%20of%20the%20body%20during%20embryonic%20growth%2C%20showcasing%20a%20possible%20new%20function%20related%20to%20Aristaless%26%23039%3B%20previously%20described%20role%20in%20appendage%20extension.%5CnCONCLUSIONS%3A%20Overall%2C%20our%20data%20suggest%20that%20while%20both%20gene%20copies%20play%20a%20role%20in%20embryogenesis%20and%20wing%20pigmentation%2C%20the%20duplicates%20have%20diverged%20temporally%20and%20mechanistically%20across%20those%20functions.%20Our%20study%20helps%20clarify%20principles%20behind%20sub-functionalization%20and%20gene%20expression%20evolution%20associated%20with%20developmental%20functions%20following%20gene%20duplication%20events.%22%2C%22date%22%3A%222023-05-11%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12915-023-01602-5%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237170114%22%2C%22PMCID%22%3A%22PMC10173497%22%2C%22ISSN%22%3A%221741-7007%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22PFITAWDN%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Bayala%20et%20al.%22%2C%22parsedDate%22%3A%222023-05-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBayala%2C%20E.%20X.%2C%20VanKuren%2C%20N.%2C%20Massardo%2C%20D.%2C%20%26amp%3B%20Kronforst%2C%20M.%20R.%20%282023%29.%20aristaless1%20has%20a%20dual%20role%20in%20appendage%20formation%20and%20wing%20color%20specification%20during%20butterfly%20development.%20%26lt%3Bi%26gt%3BBMC%20Biology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B21%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20100.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12915-023-01601-6%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12915-023-01601-6%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22aristaless1%20has%20a%20dual%20role%20in%20appendage%20formation%20and%20wing%20color%20specification%20during%20butterfly%20development%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erick%20X.%22%2C%22lastName%22%3A%22Bayala%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicholas%22%2C%22lastName%22%3A%22VanKuren%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Darli%22%2C%22lastName%22%3A%22Massardo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcus%20R.%22%2C%22lastName%22%3A%22Kronforst%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Highly%20diverse%20butterfly%20wing%20patterns%20have%20emerged%20as%20a%20powerful%20system%20for%20understanding%20the%20genetic%20basis%20of%20phenotypic%20variation.%20While%20the%20genetic%20basis%20of%20this%20pattern%20variation%20is%20being%20clarified%2C%20the%20precise%20developmental%20pathways%20linking%20genotype%20to%20phenotype%20are%20not%20well%20understood.%20The%20gene%20aristaless%2C%20which%20plays%20a%20role%20in%20appendage%20patterning%20and%20extension%2C%20has%20been%20duplicated%20in%20Lepidoptera.%20One%20copy%2C%20aristaless1%2C%20has%20been%20shown%20to%20control%20a%20white%5C%2Fyellow%20color%20switch%20in%20the%20butterfly%20Heliconius%20cydno%2C%20suggesting%20a%20novel%20function%20associated%20with%20color%20patterning%20and%20pigmentation.%20Here%20we%20investigate%20the%20developmental%20basis%20of%20al1%20in%20embryos%2C%20larvae%2C%20and%20pupae%20using%20new%20antibodies%2C%20CRISPR%5C%2FCas9%2C%20RNAi%2C%20qPCR%20assays%20of%20downstream%20targets%2C%20and%20pharmacological%20manipulation%20of%20an%20upstream%20activator.%5CnRESULTS%3A%20We%20find%20that%20Al1%20is%20expressed%20at%20the%20distal%20tips%20of%20developing%20embryonic%20appendages%20consistent%20with%20its%20ancestral%20role.%20In%20developing%20wings%2C%20we%20observe%20Al1%20accumulation%20within%20developing%20scale%20cells%20of%20white%20H.%20cydno%20during%20early%20pupation%20while%20yellow%20scale%20cells%20exhibit%20little%20Al1%20at%20this%20time%20point.%20Reduced%20Al1%20expression%20is%20also%20associated%20with%20yellow%20scale%20development%20in%20al1%20knockouts%20and%20knockdowns.%20We%20propose%20that%20Al1%20expression%20in%20future%20white%20scales%20might%20be%20related%20to%20an%20observed%20downregulation%20of%20the%20enzyme%20Cinnabar%20and%20other%20genes%20that%20synthesize%20and%20transport%20the%20yellow%20pigment%2C%203-hydroxykynurenine%20%283-OHK%29.%20Finally%2C%20we%20provide%20evidence%20that%20Al1%20activation%20is%20under%20the%20control%20of%20Wnt%20signaling.%5CnCONCLUSIONS%3A%20We%20propose%20a%20model%20in%20which%20high%20levels%20of%20Al1%20during%20early%20pupation%2C%20which%20are%20mediated%20by%20Wnt%2C%20are%20important%20for%20melanic%20pigmentation%20and%20specifying%20white%20portions%20of%20the%20wing%20while%20reduced%20levels%20of%20Al1%20during%20early%20pupation%20promote%20upregulation%20of%20proteins%20needed%20to%20move%20and%20synthesize%203-OHK%2C%20promoting%20yellow%20pigmentation.%20In%20addition%2C%20we%20discuss%20how%20the%20ancestral%20role%20of%20aristaless%20in%20appendage%20extension%20may%20be%20relevant%20in%20understanding%20the%20cellular%20mechanism%20behind%20color%20patterning%20in%20the%20context%20of%20the%20heterochrony%20hypothesis.%22%2C%22date%22%3A%222023-05-04%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12915-023-01601-6%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237143075%22%2C%22PMCID%22%3A%22PMC10161628%22%2C%22ISSN%22%3A%221741-7007%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22DEREDIG3%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Gauthier%20et%20al.%22%2C%22parsedDate%22%3A%222023-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BGauthier%2C%20J.%2C%20Meier%2C%20J.%2C%20Legeai%2C%20F.%2C%20McClure%2C%20M.%2C%20Whibley%2C%20A.%2C%20Bretaudeau%2C%20A.%2C%20Boulain%2C%20H.%2C%20Parrinello%2C%20H.%2C%20Mugford%2C%20S.%20T.%2C%20Durbin%2C%20R.%2C%20Zhou%2C%20C.%2C%20McCarthy%2C%20S.%2C%20Wheat%2C%20C.%20W.%2C%20Piron-Prunier%2C%20F.%2C%20Monsempes%2C%20C.%2C%20Fran%26%23xE7%3Bois%2C%20M.-C.%2C%20Jay%2C%20P.%2C%20No%26%23xFB%3Bs%2C%20C.%2C%20Persyn%2C%20E.%2C%20%26%23x2026%3B%20Elias%2C%20M.%20%282023%29.%20First%20chromosome%20scale%20genomes%20of%20ithomiine%20butterflies%20%28Nymphalidae%3A%20Ithomiini%29%3A%20Comparative%20models%20for%20mimicry%20genetic%20studies.%20%26lt%3Bi%26gt%3BMolecular%20Ecology%20Resources%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B23%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20872%26%23x2013%3B885.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1755-0998.13749%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1755-0998.13749%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22First%20chromosome%20scale%20genomes%20of%20ithomiine%20butterflies%20%28Nymphalidae%3A%20Ithomiini%29%3A%20Comparative%20models%20for%20mimicry%20genetic%20studies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00e9r%5Cu00e9my%22%2C%22lastName%22%3A%22Gauthier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joana%22%2C%22lastName%22%3A%22Meier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabrice%22%2C%22lastName%22%3A%22Legeai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22McClure%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annabel%22%2C%22lastName%22%3A%22Whibley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anthony%22%2C%22lastName%22%3A%22Bretaudeau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H%5Cu00e9l%5Cu00e8ne%22%2C%22lastName%22%3A%22Boulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hugues%22%2C%22lastName%22%3A%22Parrinello%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sam%20T.%22%2C%22lastName%22%3A%22Mugford%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richard%22%2C%22lastName%22%3A%22Durbin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chenxi%22%2C%22lastName%22%3A%22Zhou%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shane%22%2C%22lastName%22%3A%22McCarthy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christopher%20W.%22%2C%22lastName%22%3A%22Wheat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Florence%22%2C%22lastName%22%3A%22Piron-Prunier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christelle%22%2C%22lastName%22%3A%22Monsempes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie-Christine%22%2C%22lastName%22%3A%22Fran%5Cu00e7ois%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Jay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camille%22%2C%22lastName%22%3A%22No%5Cu00fbs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emma%22%2C%22lastName%22%3A%22Persyn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emmanuelle%22%2C%22lastName%22%3A%22Jacquin-Joly%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camille%22%2C%22lastName%22%3A%22Meslin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicolas%22%2C%22lastName%22%3A%22Montagn%5Cu00e9%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claire%22%2C%22lastName%22%3A%22Lemaitre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marianne%22%2C%22lastName%22%3A%22Elias%22%7D%5D%2C%22abstractNote%22%3A%22The%20ithomiine%20butterflies%20%28Nymphalidae%3A%20Danainae%29%20represent%20the%20largest%20known%20radiation%20of%20M%5Cu00fcllerian%20mimetic%20butterflies.%20They%20dominate%20by%20number%20the%20mimetic%20butterfly%20communities%2C%20which%20include%20species%20such%20as%20the%20iconic%20neotropical%20Heliconius%20genus.%20Recent%20studies%20on%20the%20ecology%20and%20genetics%20of%20speciation%20in%20Ithomiini%20have%20suggested%20that%20sexual%20pheromones%2C%20colour%20pattern%20and%20perhaps%20hostplant%20could%20drive%20reproductive%20isolation.%20However%2C%20no%20reference%20genome%20was%20available%20for%20Ithomiini%2C%20which%20has%20hindered%20further%20exploration%20on%20the%20genetic%20architecture%20of%20these%20candidate%20traits%2C%20and%20more%20generally%20on%20the%20genomic%20patterns%20of%20divergence.%20Here%2C%20we%20generated%20high-quality%2C%20chromosome-scale%20genome%20assemblies%20for%20two%20Melinaea%20species%2C%20M.%20marsaeus%20and%20M.%20menophilus%2C%20and%20a%20draft%20genome%20of%20the%20species%20Ithomia%20salapia.%20We%20obtained%20genomes%20with%20a%20size%20ranging%20from%20396%20to%20503%5Cu2009Mb%20across%20the%20three%20species%20and%20scaffold%20N50%20of%2040.5%20and%2023.2%5Cu00a0Mb%20for%20the%20two%20chromosome-scale%20assemblies.%20Using%20collinearity%20analyses%20we%20identified%20massive%20rearrangements%20between%20the%20two%20closely%20related%20Melinaea%20species.%20An%20annotation%20of%20transposable%20elements%20and%20gene%20content%20was%20performed%2C%20as%20well%20as%20a%20specialist%20annotation%20to%20target%20chemosensory%20genes%2C%20which%20is%20crucial%20for%20host%20plant%20detection%20and%20mate%20recognition%20in%20mimetic%20species.%20A%20comparative%20genomic%20approach%20revealed%20independent%20gene%20expansions%20in%20ithomiines%20and%20particularly%20in%20gustatory%20receptor%20genes.%20These%20first%20three%20genomes%20of%20ithomiine%20mimetic%20butterflies%20constitute%20a%20valuable%20addition%20and%20a%20welcome%20comparison%20to%20existing%20biological%20models%20such%20as%20Heliconius%2C%20and%20will%20enable%20further%20understanding%20of%20the%20mechanisms%20of%20adaptation%20in%20butterflies.%22%2C%22date%22%3A%222023-05%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2F1755-0998.13749%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236533297%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221755-0998%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22QULCU62Z%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Moura%20et%20al.%22%2C%22parsedDate%22%3A%222023-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMoura%2C%20P.%20A.%2C%20Cardoso%2C%20M.%20Z.%2C%20%26amp%3B%20Montgomery%2C%20S.%20H.%20%282023%29.%20No%20evidence%20of%20social%20learning%20in%20a%20socially%20roosting%20butterfly%20in%20an%20associative%20learning%20task.%20%26lt%3Bi%26gt%3BBiology%20Letters%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B19%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%2020220490.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frsbl.2022.0490%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frsbl.2022.0490%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22No%20evidence%20of%20social%20learning%20in%20a%20socially%20roosting%20butterfly%20in%20an%20associative%20learning%20task%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Priscila%20A.%22%2C%22lastName%22%3A%22Moura%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcio%20Z.%22%2C%22lastName%22%3A%22Cardoso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%5D%2C%22abstractNote%22%3A%22Insects%20may%20acquire%20social%20information%20by%20active%20communication%20and%20through%20inadvertent%20social%20cues.%20In%20a%20foraging%20setting%2C%20the%20latter%20may%20indicate%20the%20presence%20and%20quality%20of%20resources.%20Although%20social%20learning%20in%20foraging%20contexts%20is%20prevalent%20in%20eusocial%20species%2C%20this%20behaviour%20has%20been%20hypothesized%20to%20also%20exist%20between%20conspecifics%20in%20non-social%20species%20with%20sophisticated%20behaviours%2C%20including%20Heliconius%20butterflies.%20Heliconius%20are%20the%20only%20butterfly%20genus%20with%20active%20pollen%20feeding%2C%20a%20dietary%20innovation%20associated%20with%20a%20specialized%2C%20spatially%20faithful%20foraging%20behaviour%20known%20as%20trap-lining.%20Long-standing%20hypotheses%20suggest%20that%20Heliconius%20may%20acquire%20trap-line%20information%20by%20following%20experienced%20individuals.%20Indeed%2C%20Heliconius%20often%20aggregate%20in%20social%20roosts%2C%20which%20could%20act%20as%20%26%23039%3Binformation%20centres%26%23039%3B%2C%20and%20present%20conspecific%20following%20behaviour%2C%20enhancing%20opportunities%20for%20social%20learning.%20Here%2C%20we%20provide%20a%20direct%20test%20of%20social%20learning%20ability%20in%20Heliconius%20using%20an%20associative%20learning%20task%20in%20which%20naive%20individuals%20completed%20a%20colour%20preference%20test%20in%20the%20presence%20of%20demonstrators%20trained%20to%20feed%20randomly%20or%20with%20a%20strong%20colour%20preference.%20We%20found%20no%20evidence%20that%20Heliconius%20erato%2C%20which%20roost%20socially%2C%20used%20social%20information%20in%20this%20task.%20Combined%20with%20existing%20field%20studies%2C%20our%20results%20add%20to%20data%20which%20contradict%20the%20hypothesized%20role%20of%20social%20learning%20in%20Heliconius%20foraging%20behaviour.%22%2C%22date%22%3A%222023-05%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1098%5C%2Frsbl.2022.0490%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237194257%22%2C%22PMCID%22%3A%22PMC10189306%22%2C%22ISSN%22%3A%221744-957X%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22JS4WSVL4%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Luna%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-23%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLuna%2C%20N.%2C%20Herrera%2C%20G.%2C%20Mu%26%23xF1%3Boz%2C%20M.%2C%20S%26%23xE1%3Bnchez-Herrera%2C%20M.%2C%20Brown%2C%20A.%2C%20Khazan%2C%20E.%2C%20Pardo-Diaz%2C%20C.%2C%20Ram%26%23xED%3Brez%2C%20J.%20D.%2C%20%26amp%3B%20Salazar%2C%20C.%20%282023%29.%20Geography%20shapes%20the%20microbial%20community%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BFEMS%20Microbiology%20Ecology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B99%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20fiad028.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Ffemsec%5C%2Ffiad028%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Ffemsec%5C%2Ffiad028%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Geography%20shapes%20the%20microbial%20community%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicol%5Cu00e1s%22%2C%22lastName%22%3A%22Luna%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giovanny%22%2C%22lastName%22%3A%22Herrera%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marina%22%2C%22lastName%22%3A%22Mu%5Cu00f1oz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melissa%22%2C%22lastName%22%3A%22S%5Cu00e1nchez-Herrera%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anya%22%2C%22lastName%22%3A%22Brown%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emily%22%2C%22lastName%22%3A%22Khazan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolina%22%2C%22lastName%22%3A%22Pardo-Diaz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juan%20David%22%2C%22lastName%22%3A%22Ram%5Cu00edrez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camilo%22%2C%22lastName%22%3A%22Salazar%22%7D%5D%2C%22abstractNote%22%3A%22Heliconius%20butterflies%20are%20an%20ideal%20organism%20for%20studying%20ecology%2C%20behavior%2C%20adaptation%2C%20and%20speciation.%20These%20butterflies%20can%20be%20found%20in%20various%20locations%20and%20habitats%20in%20Central%20and%20South%20America%2C%20where%20they%20encounter%20and%20interact%20with%20different%20sources%20of%20pollen%2C%20nectar%2C%20and%20host%20plants.%20However%2C%20there%20is%20limited%20knowledge%20on%20how%20geographic%20and%20habitat%20variations%20affect%20the%20microbiota%20of%20these%20insects%2C%20and%20whether%20microbial%20associates%20play%20a%20role%20in%20their%20ability%20to%20exploit%20different%20habitats.%20To%20date%2C%20research%20on%20the%20microbial%20communities%20associated%20with%20Heliconius%20has%20mainly%20focused%20on%20host%20phylogenetic%20signal%20in%20microbiomes%20or%20microbiome%20characterization%20in%20specific%20communities%20of%20butterflies.%20In%20this%20study%2C%20we%20characterized%20the%20microbiomes%20of%20several%20species%20and%20populations%20of%20Heliconius%20from%20distant%20locations%20that%20represent%20contrasting%20environments.%20We%20found%20that%20the%20microbiota%20of%20different%20Heliconius%20species%20is%20taxonomically%20similar%20but%20vary%20in%20abundance.%20Notably%2C%20this%20variation%20is%20associated%20with%20a%20major%20geographic%20barrier-the%20Central%20Cordillera%20of%20Colombia.%20Additionally%2C%20we%20confirmed%20that%20this%20microbiota%20is%20not%20associated%20with%20pollen-feeding.%20Therefore%2C%20it%20seems%20likely%20that%20geography%20shapes%20the%20abundance%20of%20microbiota%20that%20the%20butterfly%20carries%2C%20but%20not%20the%20taxonomic%20diversity%20of%20the%20microbial%20community.%20Based%20on%20the%20current%20evidence%2C%20the%20bacterial%20microbiota%20associated%20with%20Heliconius%20does%20not%20appear%20to%20play%20a%20beneficial%20role%20for%20these%20butterflies.%22%2C%22date%22%3A%222023-03-23%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Ffemsec%5C%2Ffiad028%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236931898%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221574-6941%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%2244GDXTNF%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Luna%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-23%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLuna%2C%20N.%2C%20Herrera%2C%20G.%2C%20Mu%26%23xF1%3Boz%2C%20M.%2C%20S%26%23xE1%3Bnchez-Herrera%2C%20M.%2C%20Brown%2C%20A.%2C%20Khazan%2C%20E.%2C%20Pardo-Diaz%2C%20C.%2C%20Ram%26%23xED%3Brez%2C%20J.%20D.%2C%20%26amp%3B%20Salazar%2C%20C.%20%282023%29.%20Geography%20shapes%20the%20microbial%20community%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BFEMS%20Microbiology%20Ecology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B99%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20fiad028.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Ffemsec%5C%2Ffiad028%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Ffemsec%5C%2Ffiad028%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Geography%20shapes%20the%20microbial%20community%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicol%5Cu00e1s%22%2C%22lastName%22%3A%22Luna%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giovanny%22%2C%22lastName%22%3A%22Herrera%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marina%22%2C%22lastName%22%3A%22Mu%5Cu00f1oz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melissa%22%2C%22lastName%22%3A%22S%5Cu00e1nchez-Herrera%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anya%22%2C%22lastName%22%3A%22Brown%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emily%22%2C%22lastName%22%3A%22Khazan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolina%22%2C%22lastName%22%3A%22Pardo-Diaz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juan%20David%22%2C%22lastName%22%3A%22Ram%5Cu00edrez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camilo%22%2C%22lastName%22%3A%22Salazar%22%7D%5D%2C%22abstractNote%22%3A%22Heliconius%20butterflies%20are%20an%20ideal%20organism%20for%20studying%20ecology%2C%20behavior%2C%20adaptation%2C%20and%20speciation.%20These%20butterflies%20can%20be%20found%20in%20various%20locations%20and%20habitats%20in%20Central%20and%20South%20America%2C%20where%20they%20encounter%20and%20interact%20with%20different%20sources%20of%20pollen%2C%20nectar%2C%20and%20host%20plants.%20However%2C%20there%20is%20limited%20knowledge%20on%20how%20geographic%20and%20habitat%20variations%20affect%20the%20microbiota%20of%20these%20insects%2C%20and%20whether%20microbial%20associates%20play%20a%20role%20in%20their%20ability%20to%20exploit%20different%20habitats.%20To%20date%2C%20research%20on%20the%20microbial%20communities%20associated%20with%20Heliconius%20has%20mainly%20focused%20on%20host%20phylogenetic%20signal%20in%20microbiomes%20or%20microbiome%20characterization%20in%20specific%20communities%20of%20butterflies.%20In%20this%20study%2C%20we%20characterized%20the%20microbiomes%20of%20several%20species%20and%20populations%20of%20Heliconius%20from%20distant%20locations%20that%20represent%20contrasting%20environments.%20We%20found%20that%20the%20microbiota%20of%20different%20Heliconius%20species%20is%20taxonomically%20similar%20but%20vary%20in%20abundance.%20Notably%2C%20this%20variation%20is%20associated%20with%20a%20major%20geographic%20barrier-the%20Central%20Cordillera%20of%20Colombia.%20Additionally%2C%20we%20confirmed%20that%20this%20microbiota%20is%20not%20associated%20with%20pollen-feeding.%20Therefore%2C%20it%20seems%20likely%20that%20geography%20shapes%20the%20abundance%20of%20microbiota%20that%20the%20butterfly%20carries%2C%20but%20not%20the%20taxonomic%20diversity%20of%20the%20microbial%20community.%20Based%20on%20the%20current%20evidence%2C%20the%20bacterial%20microbiota%20associated%20with%20Heliconius%20does%20not%20appear%20to%20play%20a%20beneficial%20role%20for%20these%20butterflies.%22%2C%22date%22%3A%222023-03-23%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Ffemsec%5C%2Ffiad028%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236931898%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221574-6941%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A33%3A28Z%22%7D%7D%2C%7B%22key%22%3A%22H27FVBWP%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Hausmann%20et%20al.%22%2C%22parsedDate%22%3A%222023-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHausmann%2C%20A.%20E.%2C%20Freire%2C%20M.%2C%20Alfthan%2C%20S.%20A.%2C%20Kuo%2C%20C.-Y.%2C%20Linares%2C%20M.%2C%20McMillan%2C%20O.%2C%20Pardo-Diaz%2C%20C.%2C%20Salazar%2C%20C.%2C%20%26amp%3B%20Merrill%2C%20R.%20M.%20%282023%29.%20Does%20sexual%20conflict%20contribute%20to%20the%20evolution%20of%20novel%20warning%20patterns%3F%20%26lt%3Bi%26gt%3BJournal%20of%20Evolutionary%20Biology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B36%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20563%26%23x2013%3B578.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjeb.14151%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjeb.14151%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Does%20sexual%20conflict%20contribute%20to%20the%20evolution%20of%20novel%20warning%20patterns%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%20E.%22%2C%22lastName%22%3A%22Hausmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mar%5Cu00edlia%22%2C%22lastName%22%3A%22Freire%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sara%20A.%22%2C%22lastName%22%3A%22Alfthan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chi-Yun%22%2C%22lastName%22%3A%22Kuo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mauricio%22%2C%22lastName%22%3A%22Linares%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolina%22%2C%22lastName%22%3A%22Pardo-Diaz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camilo%22%2C%22lastName%22%3A%22Salazar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richard%20M.%22%2C%22lastName%22%3A%22Merrill%22%7D%5D%2C%22abstractNote%22%3A%22Why%20warning%20patterns%20are%20so%20diverse%20is%20an%20enduring%20evolutionary%20puzzle.%20Because%20predators%20associate%20particular%20patterns%20with%20unpleasant%20experiences%2C%20an%20individual%26%23039%3Bs%20predation%20risk%20should%20decrease%20as%20the%20local%20density%20of%20its%20warning%20pattern%20increases%2C%20promoting%20pattern%20monomorphism.%20Distasteful%20Heliconius%20butterflies%20are%20known%20for%20their%20diversity%20of%20warning%20patterns.%20Here%2C%20we%20explore%20whether%20interlocus%20sexual%20conflict%20can%20contribute%20to%20their%20diversification.%20Male%20Heliconius%20use%20warning%20patterns%20as%20mating%20cues%2C%20but%20mated%20females%20may%20suffer%20costs%20if%20this%20leads%20to%20disturbance%2C%20favouring%20novel%20patterns.%20Using%20simulations%2C%20we%20show%20that%20under%20our%20model%20conditions%20drift%20alone%20is%20unlikely%20to%20cause%20pattern%20diversification%2C%20but%20that%20sexual%20conflict%20can%20assist%20such%20a%20process.%20We%20also%20find%20that%20genetic%20architecture%20influences%20the%20evolution%20of%20male%20preferences%2C%20which%20track%20changes%20in%20warning%20pattern%20due%20to%20sexual%20selection.%20When%20male%20attraction%20imposes%20costs%20on%20females%2C%20this%20affects%20the%20speed%20at%20which%20novel%20pattern%20alleles%20increase.%20In%20two%20experiments%2C%20females%20laid%20fewer%20eggs%20with%20males%20present.%20However%2C%20although%20males%20in%20one%20experiment%20showed%20less%20interest%20in%20females%20with%20manipulated%20patterns%2C%20we%20found%20no%20evidence%20that%20female%20colouration%20mitigates%20sex-specific%20costs.%20Overall%2C%20male%20attraction%20to%20conspecific%20warning%20patterns%20may%20impose%20an%20unrecognized%20cost%20on%20Heliconius%20females%2C%20but%20further%20work%20is%20required%20to%20determine%20this%20experimentally.%22%2C%22date%22%3A%222023-03%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2Fjeb.14151%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236702779%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221420-9101%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%2262D4BMRY%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Bastide%20et%20al.%22%2C%22parsedDate%22%3A%222023-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBastide%2C%20H.%2C%20Saenko%2C%20S.%20V.%2C%20Chouteau%2C%20M.%2C%20Joron%2C%20M.%2C%20%26amp%3B%20Llaurens%2C%20V.%20%282023%29.%20Dominance%20mechanisms%20in%20supergene%20alleles%20controlling%20butterfly%20wing%20pattern%20variation%3A%20insights%20from%20gene%20expression%20in%20Heliconius%20numata.%20%26lt%3Bi%26gt%3BHeredity%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B130%26lt%3B%5C%2Fi%26gt%3B%282%29%2C%2092%26%23x2013%3B98.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41437-022-00583-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41437-022-00583-5%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Dominance%20mechanisms%20in%20supergene%20alleles%20controlling%20butterfly%20wing%20pattern%20variation%3A%20insights%20from%20gene%20expression%20in%20Heliconius%20numata%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H%5Cu00e9lo%5Cu00efse%22%2C%22lastName%22%3A%22Bastide%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Suzanne%20V.%22%2C%22lastName%22%3A%22Saenko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mathieu%22%2C%22lastName%22%3A%22Chouteau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mathieu%22%2C%22lastName%22%3A%22Joron%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Violaine%22%2C%22lastName%22%3A%22Llaurens%22%7D%5D%2C%22abstractNote%22%3A%22Loci%20under%20balancing%20selection%2C%20where%20multiple%20alleles%20are%20maintained%2C%20offer%20a%20relevant%20opportunity%20to%20investigate%20the%20role%20of%20natural%20selection%20in%20shaping%20genetic%20dominance%3A%20the%20high%20frequency%20of%20heterozygotes%20at%20these%20loci%20has%20been%20shown%20to%20enable%20the%20evolution%20of%20dominance%20among%20alleles.%20In%20the%20butterfly%20Heliconius%20numata%2C%20mimetic%20wing%20color%20variations%20are%20controlled%20by%20an%20inversion%20polymorphism%20of%20a%20circa%202%5Cu2009Mb%20genomic%20region%20%28supergene%20P%29%2C%20with%20strong%20dominance%20between%20sympatric%20alleles.%20To%20test%20how%20differences%20in%20dominance%20observed%20on%20wing%20patterns%20correlate%20with%20variations%20in%20expression%20levels%20throughout%20the%20supergene%20region%2C%20we%20sequenced%20the%20complete%20transcriptome%20of%20heterozygotes%20at%20the%20prepupal%20stage%20and%20compared%20it%20to%20corresponding%20homozygotes.%20By%20defining%20dominance%20based%20on%20non-overlapping%20ranges%20of%20transcript%20expression%20between%20genotypes%2C%20we%20found%20contrasting%20patterns%20of%20dominance%20between%20the%20supergene%20and%20the%20rest%20of%20the%20genome%3B%20the%20patterns%20of%20transcript%20expression%20in%20the%20heterozygotes%20were%20more%20similar%20to%20the%20expression%20observed%20in%20the%20dominant%20homozygotes%20in%20the%20supergene%20region.%20Dominance%20also%20differed%20among%20the%20three%20subinversions%20of%20the%20supergene%2C%20suggesting%20possible%20epistatic%20interactions%20among%20their%20gene%20contents%20underlying%20dominance%20evolution.%20We%20found%20the%20expression%20pattern%20of%20the%20melanization%20gene%20cortex%20located%20in%20the%20P-region%20to%20predict%20wing%20pattern%20phenotype%20in%20the%20heterozygote.%20We%20also%20identify%20new%20candidate%20genes%20that%20are%20potentially%20involved%20in%20mimetic%20color%20pattern%20variations%20highlighting%20the%20relevance%20of%20transcriptomic%20analyses%20in%20heterozygotes%20to%20pinpoint%20candidate%20genes%20in%20non-recombining%20regions.%22%2C%22date%22%3A%222023-02%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41437-022-00583-5%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236522413%22%2C%22PMCID%22%3A%22PMC9905084%22%2C%22ISSN%22%3A%221365-2540%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22H9HUTJ9M%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Srygley%20et%20al.%22%2C%22parsedDate%22%3A%222023-01-21%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BSrygley%2C%20R.%20B.%2C%20Dudley%2C%20R.%2C%20Hernandez%2C%20E.%20J.%2C%20Kainz%2C%20F.%2C%20Riveros%2C%20A.%20J.%2C%20%26amp%3B%20Ellington%2C%20C.%20P.%20%282023%29.%20Quantifying%20the%20Aerodynamic%20Power%20Required%20for%20Flight%20and%20Testing%20for%20Adaptive%20Wind%20Drift%20in%20Passion-Vine%20Butterflies%20Heliconius%20sara%20%28Lepidoptera%3A%20Nymphalidae%29.%20%26lt%3Bi%26gt%3BInsects%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B14%26lt%3B%5C%2Fi%26gt%3B%282%29%2C%20112.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Finsects14020112%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Finsects14020112%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Quantifying%20the%20Aerodynamic%20Power%20Required%20for%20Flight%20and%20Testing%20for%20Adaptive%20Wind%20Drift%20in%20Passion-Vine%20Butterflies%20Heliconius%20sara%20%28Lepidoptera%3A%20Nymphalidae%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%20B.%22%2C%22lastName%22%3A%22Srygley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Dudley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Edgar%20J.%22%2C%22lastName%22%3A%22Hernandez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franz%22%2C%22lastName%22%3A%22Kainz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andre%20J.%22%2C%22lastName%22%3A%22Riveros%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlie%20P.%22%2C%22lastName%22%3A%22Ellington%22%7D%5D%2C%22abstractNote%22%3A%22Although%20theoretical%20work%20on%20optimal%20migration%20has%20been%20largely%20restricted%20to%20birds%2C%20relevant%20free-flight%20data%20are%20now%20becoming%20available%20for%20migratory%20insects.%20Here%20we%20report%2C%20for%20the%20first%20time%20in%20passion-vine%20butterflies%2C%20that%20Heliconius%20sara%20migrates%20directionally.%20To%20test%20optimal%20migration%20models%20for%20insects%2C%20we%20quantified%20the%20aerodynamic%20power%20curve%20for%20free-flying%20H.%20sara%20as%20they%20migrated%20across%20the%20Panama%20Canal.%20Using%20synchronized%20stereo-images%20from%20high-speed%20video%20cameras%2C%20we%20reconstructed%20three-dimensional%20flight%20kinematics%20of%20H.%20sara%20migrating%20naturally%20across%20the%20Panama%20Canal.%20We%20also%20reconstructed%20flight%20kinematics%20from%20a%20single-camera%20view%20of%20butterflies%20flying%20through%20a%20flight%20tunnel.%20We%20calculated%20the%20power%20requirements%20for%20flight%20for%20H.%20sara%20over%20a%20range%20of%20flight%20velocities.%20The%20relationship%20between%20aerodynamic%20power%20and%20velocity%20was%20%26quot%3BJ%26quot%3B-shaped%20across%20the%20measured%20velocities%20with%20a%20minimum%20power%20velocity%20of%200.9%20m%5C%2Fs%20and%20a%20maximum%20range%20velocity%20of%202.25%20m%5C%2Fs.%20Migrating%20H.%20sara%20did%20not%20compensate%20for%20crosswind%20drift.%20Changes%20in%20airspeed%20with%20tailwind%20drift%20were%20consistent%20with%20the%20null%20hypothesis%20that%20H.%20sara%20did%20not%20compensate%20for%20tailwind%20drift%2C%20but%20they%20were%20also%20not%20significantly%20different%20from%20those%20predicted%20to%20maximize%20the%20migratory%20range%20of%20the%20insects.%22%2C%22date%22%3A%222023-01-21%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.3390%5C%2Finsects14020112%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236835681%22%2C%22PMCID%22%3A%22PMC9959374%22%2C%22ISSN%22%3A%222075-4450%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22VHV9KIXN%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Rosado-Tristani%20and%20Rodr%5Cu00edguez-Mart%5Cu00ednez%22%2C%22parsedDate%22%3A%222023%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BRosado-Tristani%2C%20D.%20A.%2C%20%26amp%3B%20Rodr%26%23xED%3Bguez-Mart%26%23xED%3Bnez%2C%20J.%20A.%20%282023%29.%20CREPE%3A%20a%20Shiny%20app%20for%20transcription%20factor%20cataloguing.%20%26lt%3Bi%26gt%3BBioinformatics%20Advances%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B3%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20vbad055.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fbioadv%5C%2Fvbad055%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fbioadv%5C%2Fvbad055%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22CREPE%3A%20a%20Shiny%20app%20for%20transcription%20factor%20cataloguing%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diego%20A.%22%2C%22lastName%22%3A%22Rosado-Tristani%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jos%5Cu00e9%20A.%22%2C%22lastName%22%3A%22Rodr%5Cu00edguez-Mart%5Cu00ednez%22%7D%5D%2C%22abstractNote%22%3A%22SUMMARY%3A%20Transcription%20factors%20%28TFs%29%20are%20proteins%20that%20directly%20interpret%20the%20genome%20to%20regulate%20gene%20expression%20and%20determine%20cellular%20phenotypes.%20TF%20identification%20is%20a%20common%20first%20step%20in%20unraveling%20gene%20regulatory%20networks.%20We%20present%20CREPE%2C%20an%20R%20Shiny%20app%20to%20catalogue%20and%20annotate%20TFs.%20CREPE%20was%20benchmarked%20against%20curated%20human%20TF%20datasets.%20Next%2C%20we%20use%20CREPE%20to%20explore%20the%20TF%20repertoires%20of%20Heliconius%20erato%20and%20Heliconius%20melpomene%20butterflies.%5CnAVAILABILITY%20AND%20IMPLEMENTATION%3A%20CREPE%20is%20available%20as%20a%20Shiny%20app%20package%20available%20at%20GitHub%20%28github.com%5C%2Fdirostri%5C%2FCREPE%29.%5CnSUPPLEMENTARY%20INFORMATION%3A%20Supplementary%20data%20are%20available%20at%20Bioinformatics%20Advances%20online.%22%2C%22date%22%3A%222023%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fbioadv%5C%2Fvbad055%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2237153629%22%2C%22PMCID%22%3A%22PMC10162806%22%2C%22ISSN%22%3A%222635-0041%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22M8YW7BW4%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Wu%20et%20al.%22%2C%22parsedDate%22%3A%222022-11-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BWu%2C%20N.%2C%20Evans%2C%20E.%2C%20van%20Schooten%2C%20B.%2C%20Mel%26%23xE9%3Bndez-Rosa%2C%20J.%2C%20Ortiz%2C%20Y.%2C%20Planas%20Soto-Navarro%2C%20S.%20M.%2C%20Van%20Belleghem%2C%20S.%20M.%2C%20Counterman%2C%20B.%20A.%2C%20Papa%2C%20R.%2C%20%26amp%3B%20Zhang%2C%20W.%20%282022%29.%20Widespread%20Gene%20Expression%20Divergence%20in%20Butterfly%20Sensory%20Tissues%20Plays%20a%20Fundamental%20Role%20During%20Reproductive%20Isolation%20and%20Speciation.%20%26lt%3Bi%26gt%3BMolecular%20Biology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B39%26lt%3B%5C%2Fi%26gt%3B%2811%29%2C%20msac225.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsac225%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsac225%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Widespread%20Gene%20Expression%20Divergence%20in%20Butterfly%20Sensory%20Tissues%20Plays%20a%20Fundamental%20Role%20During%20Reproductive%20Isolation%20and%20Speciation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ningning%22%2C%22lastName%22%3A%22Wu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elizabeth%22%2C%22lastName%22%3A%22Evans%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bas%22%2C%22lastName%22%3A%22van%20Schooten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jesyka%22%2C%22lastName%22%3A%22Mel%5Cu00e9ndez-Rosa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yadira%22%2C%22lastName%22%3A%22Ortiz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silvia%20M.%22%2C%22lastName%22%3A%22Planas%20Soto-Navarro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Steven%20M.%22%2C%22lastName%22%3A%22Van%20Belleghem%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Brian%20A.%22%2C%22lastName%22%3A%22Counterman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Riccardo%22%2C%22lastName%22%3A%22Papa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wei%22%2C%22lastName%22%3A%22Zhang%22%7D%5D%2C%22abstractNote%22%3A%22Neotropical%20Heliconius%20butterflies%20are%20well%20known%20for%20their%20intricate%20behaviors%20and%20multiple%20instances%20of%20incipient%20speciation.%20Chemosensing%20plays%20a%20fundamental%20role%20in%20the%20life%20history%20of%20these%20groups%20of%20butterflies%20and%20in%20the%20establishment%20of%20reproductive%20isolation.%20However%2C%20chemical%20communication%20involves%20synergistic%20sensory%20and%20accessory%20functions%2C%20and%20it%20remains%20challenging%20to%20investigate%20the%20molecular%20mechanisms%20underlying%20behavioral%20differences.%20Here%2C%20we%20examine%20the%20gene%20expression%20profiles%20and%20genomic%20divergence%20of%20three%20sensory%20tissues%20%28antennae%2C%20legs%2C%20and%20mouthparts%29%20between%20sexes%20%28females%20and%20males%29%20and%20life%20stages%20%28different%20adult%20stages%29%20in%20two%20hybridizing%20butterflies%2C%20Heliconius%20melpomene%20and%20Heliconius%20cydno.%20By%20integrating%20comparative%20transcriptomic%20and%20population%20genomic%20approaches%2C%20we%20found%20evidence%20of%20widespread%20gene%20expression%20divergence%2C%20supporting%20a%20crucial%20role%20of%20sensory%20tissues%20in%20the%20establishment%20of%20species%20barriers.%20We%20also%20show%20that%20sensory%20diversification%20increases%20in%20a%20manner%20consistent%20with%20evolutionary%20divergence%20based%20on%20comparison%20with%20the%20more%20distantly%20related%20species%20Heliconius%20charithonia.%20The%20findings%20of%20our%20study%20strongly%20support%20the%20unique%20chemosensory%20function%20of%20antennae%20in%20all%20three%20species%2C%20the%20importance%20of%20the%20Z%20chromosome%20in%20interspecific%20divergence%2C%20and%20the%20nonnegligible%20role%20of%20nonchemosensory%20genes%20in%20the%20divergence%20of%20chemosensory%20tissues.%20Collectively%2C%20our%20results%20provide%20a%20genome-wide%20illustration%20of%20diversification%20in%20the%20chemosensory%20system%20under%20incomplete%20reproductive%20isolation%2C%20revealing%20strong%20molecular%20separation%20in%20the%20early%20stage%20of%20speciation.%20Here%2C%20we%20provide%20a%20unique%20perspective%20and%20relevant%20view%20of%20the%20genetic%20architecture%20%28sensory%20and%20accessory%20functions%29%20of%20chemosensing%20beyond%20the%20classic%20chemosensory%20gene%20families%2C%20leading%20to%20a%20better%20understanding%20of%20the%20magnitude%20and%20complexity%20of%20molecular%20changes%20in%20sensory%20tissues%20that%20contribute%20to%20the%20establishment%20of%20reproductive%20isolation%20and%20speciation.%22%2C%22date%22%3A%222022-11-03%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fmolbev%5C%2Fmsac225%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236251882%22%2C%22PMCID%22%3A%22PMC9641979%22%2C%22ISSN%22%3A%221537-1719%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22IICRHM2A%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Opler%20et%20al.%22%2C%22parsedDate%22%3A%222022-10-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BOpler%2C%20P.%2C%20Stout%2C%20T.%2C%20Back%2C%20W.%2C%20Zhang%2C%20J.%2C%20Cong%2C%20Q.%2C%20Shen%2C%20J.%2C%20%26amp%3B%20Grishin%2C%20N.%20%282022%29.%20DNA%20barcodes%20reveal%20different%20speciation%20scenarios%20in%20the%20four%20North%20American%20Anthocharis%20Boisduval%2C%20Rambur%2C%20%5BDumenil%5D%20%26amp%3B%20Graslin%2C%20%5B1833%5D%20%28Lepidoptera%3A%20Pieridae%3A%20Pierinae%3A%20Anthocharidini%29%20species%20groups.%20%26lt%3Bi%26gt%3BZOOTAXA%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B5194%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20519%26%23x2013%3B539.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.11646%5C%2Fzootaxa.5194.4.3%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.11646%5C%2Fzootaxa.5194.4.3%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22DNA%20barcodes%20reveal%20different%20speciation%20scenarios%20in%20the%20four%20North%20American%20Anthocharis%20Boisduval%2C%20Rambur%2C%20%5BDumenil%5D%20%26%20Graslin%2C%20%5B1833%5D%20%28Lepidoptera%3A%20Pieridae%3A%20Pierinae%3A%20Anthocharidini%29%20species%20groups%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22PA%22%2C%22lastName%22%3A%22Opler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22TL%22%2C%22lastName%22%3A%22Stout%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W%22%2C%22lastName%22%3A%22Back%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%22%2C%22lastName%22%3A%22Zhang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Q%22%2C%22lastName%22%3A%22Cong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22JH%22%2C%22lastName%22%3A%22Shen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22NV%22%2C%22lastName%22%3A%22Grishin%22%7D%5D%2C%22abstractNote%22%3A%22The%20mitochondrial%20DNA%20COI%20barcode%20segment%20sequenced%20from%20American%20Anthocharis%20specimens%20across%20their%20distribution%20ranges%20partitions%20them%20into%20four%20well-separated%20species%20groups%20and%20reveals%20different%20levels%20of%20differentiation%20within%20these%20groups.%20The%20lanceolata%20group%20experienced%20the%20deepest%20divergence.%20About%202.7%25%20barcode%20difference%20separates%20the%20two%20species%3A%20A.%20lanceolata%20Lucas%2C%201852%20including%20A.%20lanceolata%20australis%20%28F.%20Grinnell%2C%201908%29%2C%20from%20A.%20desertolimbus%20J.%20Emmel%2C%20T.%20Emmel%20%26amp%3B%20Mattoon%2C%201998.%20The%20sara%20group%20consists%20of%20three%20species%20distinctly%20defined%20by%20more%20than%202%25%20sequence%20divergence%3A%20A.%20sara%20Lucas%2C%201852%2C%20A.%20julia%20W.%20H.%20Edwards%2C%201872%2C%20and%20A.%20thoosa%20%28Scudder%2C%201878%29.%20Our%20treatment%20is%20fully%20consistent%20with%20morphological%20evidence%20largely%20based%20on%20the%20characters%20of%20fifth%20instar%20larvae%20and%20pupal%20cone%20curvature%20%28Stout%2C%202005%2C%202018%29.%20In%20barcodes%2C%20it%20is%20not%20possible%20to%20see%20evidence%20of%20introgression%20or%20hybridization%20between%20the%20three%20species%2C%20and%20identification%20by%20morphology%20of%20immature%20stages%20always%20agrees%20with%20DNA%20barcode%20identification.%20Interestingly%2C%20A.%20thoosa%20exhibited%20the%20largest%20intraspecific%20divergence%20in%20DNA%20barcodes%2C%20and%20several%20of%20its%20metapopulations%20are%20identifiable%20by%20haplotypes.%20The%20cethura%20group%20is%20characterized%20by%20the%20smallest%20divergence%20and%20is%20best%20considered%20as%20a%20single%20species%20variable%20in%20expression%20of%20yellow%20coloration%3A%20A%20cethura%20C.%20Felder%20%26amp%3B%20R.%20Felder%2C%201865.%20Notably%2C%20the%20most%20sexually%20dimorphic%20subspecies%20A.%20cethura%20morrisoni%20W.%20H.%20Edwards%2C%201881%20is%20the%20most%20distinct%20by%20the%20barcodes.%20Finally%2C%20the%20midea%20group%20barcodes%20do%20not%20always%20separate%20A.%20midea%20%28Hubner%2C%20%5B1809%5D%29%20and%20A.%20limonea%20%28A.%20Butler%2C%201871%29%20and%20we%20observe%20gradual%20accumulation%20of%20differences%20from%20north%20%28northeastern%20USA%29%20to%20south%20%28Hidalgo%2C%20Mexico%29.%20This%20barcode%20gradient%20suggests%20a%20recent%20origin%20of%20the%20two%20midea%20group%20species%20and%20provides%20another%20example%20of%20vicariant%20sister%20species%20well%20defined%20by%20morphology%2C%20ecology%20and%20geography%2C%20but%20not%20necessarily%20by%20DNA%20barcodes.%22%2C%22date%22%3A%222022%20OCT%207%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.11646%5C%2Fzootaxa.5194.4.3%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%22%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221175-5326%22%2C%22language%22%3A%22English%22%2C%22collections%22%3A%5B%22W9PMW99E%22%5D%2C%22dateModified%22%3A%222025-11-10T15%3A58%3A36Z%22%7D%7D%2C%7B%22key%22%3A%22RULVKSMG%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Ruggieri%20et%20al.%22%2C%22parsedDate%22%3A%222022-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BRuggieri%2C%20A.%20A.%2C%20Livraghi%2C%20L.%2C%20Lewis%2C%20J.%20J.%2C%20Evans%2C%20E.%2C%20Cicconardi%2C%20F.%2C%20Hebberecht%2C%20L.%2C%20Ortiz-Ruiz%2C%20Y.%2C%20Montgomery%2C%20S.%20H.%2C%20Ghezzi%2C%20A.%2C%20Rodriguez-Martinez%2C%20J.%20A.%2C%20Jiggins%2C%20C.%20D.%2C%20McMillan%2C%20W.%20O.%2C%20Counterman%2C%20B.%20A.%2C%20Papa%2C%20R.%2C%20%26amp%3B%20Van%20Belleghem%2C%20S.%20M.%20%282022%29.%20A%20butterfly%20pan-genome%20reveals%20that%20a%20large%20amount%20of%20structural%20variation%20underlies%20the%20evolution%20of%20chromatin%20accessibility.%20%26lt%3Bi%26gt%3BGenome%20Research%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B32%26lt%3B%5C%2Fi%26gt%3B%2810%29%2C%201862%26%23x2013%3B1875.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1101%5C%2Fgr.276839.122%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1101%5C%2Fgr.276839.122%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22A%20butterfly%20pan-genome%20reveals%20that%20a%20large%20amount%20of%20structural%20variation%20underlies%20the%20evolution%20of%20chromatin%20accessibility%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angelo%20A.%22%2C%22lastName%22%3A%22Ruggieri%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Luca%22%2C%22lastName%22%3A%22Livraghi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20J.%22%2C%22lastName%22%3A%22Lewis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elizabeth%22%2C%22lastName%22%3A%22Evans%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francesco%22%2C%22lastName%22%3A%22Cicconardi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Hebberecht%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yadira%22%2C%22lastName%22%3A%22Ortiz-Ruiz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alfredo%22%2C%22lastName%22%3A%22Ghezzi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jos%5Cu00e9%20Arcadio%22%2C%22lastName%22%3A%22Rodriguez-Martinez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%20D.%22%2C%22lastName%22%3A%22Jiggins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Brian%20A.%22%2C%22lastName%22%3A%22Counterman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Riccardo%22%2C%22lastName%22%3A%22Papa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Steven%20M.%22%2C%22lastName%22%3A%22Van%20Belleghem%22%7D%5D%2C%22abstractNote%22%3A%22Despite%20insertions%20and%20deletions%20being%20the%20most%20common%20structural%20variants%20%28SVs%29%20found%20across%20genomes%2C%20not%20much%20is%20known%20about%20how%20much%20these%20SVs%20vary%20within%20populations%20and%20between%20closely%20related%20species%2C%20nor%20their%20significance%20in%20evolution.%20To%20address%20these%20questions%2C%20we%20characterized%20the%20evolution%20of%20indel%20SVs%20using%20genome%20assemblies%20of%20three%20closely%20related%20Heliconius%20butterfly%20species.%20Over%20the%20relatively%20short%20evolutionary%20timescales%20investigated%2C%20up%20to%2018.0%25%20of%20the%20genome%20was%20composed%20of%20indels%20between%20two%20haplotypes%20of%20an%20individual%20Heliconius%20charithonia%20butterfly%20and%20up%20to%2062.7%25%20included%20lineage-specific%20SVs%20between%20the%20genomes%20of%20the%20most%20distant%20species%20%2811%20Mya%29.%20Lineage-specific%20sequences%20were%20mostly%20characterized%20as%20transposable%20elements%20%28TEs%29%20inserted%20at%20random%20throughout%20the%20genome%20and%20their%20overall%20distribution%20was%20similarly%20affected%20by%20linked%20selection%20as%20single%20nucleotide%20substitutions.%20Using%20chromatin%20accessibility%20profiles%20%28i.e.%2C%20ATAC-seq%29%20of%20head%20tissue%20in%20caterpillars%20to%20identify%20sequences%20with%20potential%20cis-regulatory%20function%2C%20we%20found%20that%20out%20of%20the%2031%2C066%20identified%20differences%20in%20chromatin%20accessibility%20between%20species%2C%2030.4%25%20were%20within%20lineage-specific%20SVs%20and%209.4%25%20were%20characterized%20as%20TE%20insertions.%20These%20TE%20insertions%20were%20localized%20closer%20to%20gene%20transcription%20start%20sites%20than%20expected%20at%20random%20and%20were%20enriched%20for%20sites%20with%20significant%20resemblance%20to%20several%20transcription%20factor%20binding%20sites%20with%20known%20function%20in%20neuron%20development%20in%20Drosophila%20We%20also%20identified%2024%20TE%20insertions%20with%20head-specific%20chromatin%20accessibility.%20Our%20results%20show%20high%20rates%20of%20structural%20genome%20evolution%20that%20were%20previously%20overlooked%20in%20comparative%20genomic%20studies%20and%20suggest%20a%20high%20potential%20for%20structural%20variation%20to%20serve%20as%20raw%20material%20for%20adaptive%20evolution.%22%2C%22date%22%3A%222022-10%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1101%5C%2Fgr.276839.122%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236109150%22%2C%22PMCID%22%3A%22PMC9712634%22%2C%22ISSN%22%3A%221549-5469%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22TUQ982JN%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Pereira%20Martins%20et%20al.%22%2C%22parsedDate%22%3A%222022-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPereira%20Martins%2C%20A.%20R.%2C%20Martins%2C%20L.%20P.%2C%20Ho%2C%20W.-Z.%2C%20McMillan%2C%20W.%20O.%2C%20Ready%2C%20J.%20S.%2C%20%26amp%3B%20Barrett%2C%20R.%20%282022%29.%20Scale-dependent%20environmental%20effects%20on%20phenotypic%20distributions%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BEcology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B12%26lt%3B%5C%2Fi%26gt%3B%289%29%2C%20e9286.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.9286%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.9286%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Scale-dependent%20environmental%20effects%20on%20phenotypic%20distributions%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ananda%20R.%22%2C%22lastName%22%3A%22Pereira%20Martins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lucas%20P.%22%2C%22lastName%22%3A%22Martins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wing-Zheng%22%2C%22lastName%22%3A%22Ho%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonathan%20S.%22%2C%22lastName%22%3A%22Ready%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rowan%22%2C%22lastName%22%3A%22Barrett%22%7D%5D%2C%22abstractNote%22%3A%22Identifying%20the%20relative%20importance%20of%20different%20mechanisms%20responsible%20for%20the%20emergence%20and%20maintenance%20of%20phenotypic%20diversity%20can%20be%20challenging%2C%20as%20multiple%20selective%20pressures%20and%20stochastic%20events%20are%20involved%20in%20these%20processes.%20Therefore%2C%20testing%20how%20environmental%20conditions%20shape%20the%20distribution%20of%20phenotypes%20can%20offer%20important%20insights%20on%20local%20adaptation%2C%20divergence%2C%20and%20speciation.%20The%20red-yellow%20M%5Cu00fcllerian%20mimicry%20ring%20of%20Heliconius%20butterflies%20exhibits%20a%20wide%20diversity%20of%20color%20patterns%20across%20the%20Neotropics%20and%20is%20involved%20in%20multiple%20hybrid%20zones%2C%20making%20it%20a%20powerful%20system%20to%20investigate%20environmental%20drivers%20of%20phenotypic%20distributions.%20Using%20the%20distantly%20related%20Heliconius%20erato%20and%20Heliconius%20melpomene%20co-mimics%20and%20a%20multiscale%20distribution%20approach%2C%20we%20investigated%20whether%20distinct%20phenotypes%20of%20these%20species%20are%20associated%20with%20different%20environmental%20conditions.%20We%20show%20that%20Heliconius%20red-yellow%20phenotypic%20distribution%20is%20strongly%20driven%20by%20environmental%20gradients%20%28especially%20thermal%20and%20precipitation%20variables%29%2C%20but%20that%20phenotype%20and%20environment%20associations%20vary%20with%20spatial%20scale.%20While%20co-mimics%20are%20usually%20predicted%20to%20occur%20in%20similar%20environments%20at%20large%20spatial%20scales%2C%20patterns%20at%20local%20scales%20are%20not%20always%20consistent%20%28i.e.%2C%20different%20variables%20are%20best%20predictors%20of%20phenotypic%20occurrence%20in%20different%20locations%29%20or%20congruent%20%28i.e.%2C%20co-mimics%20show%20distinct%20associations%20with%20environment%29.%20We%20suggest%20that%20large-scale%20analyses%20are%20important%20for%20identifying%20how%20environmental%20factors%20shape%20broad%20mimetic%20phenotypic%20distributions%2C%20but%20that%20local%20studies%20are%20essential%20to%20understand%20the%20context-dependent%20biotic%2C%20abiotic%2C%20and%20historical%20mechanisms%20driving%20finer-scale%20phenotypic%20transitions.%22%2C%22date%22%3A%222022-09%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fece3.9286%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236177141%22%2C%22PMCID%22%3A%22PMC9471044%22%2C%22ISSN%22%3A%222045-7758%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A33%3A28Z%22%7D%7D%2C%7B%22key%22%3A%22FKQ3PL3B%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Pereira%20Martins%20et%20al.%22%2C%22parsedDate%22%3A%222022-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPereira%20Martins%2C%20A.%20R.%2C%20Martins%2C%20L.%20P.%2C%20Ho%2C%20W.-Z.%2C%20McMillan%2C%20W.%20O.%2C%20Ready%2C%20J.%20S.%2C%20%26amp%3B%20Barrett%2C%20R.%20%282022%29.%20Scale-dependent%20environmental%20effects%20on%20phenotypic%20distributions%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BEcology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B12%26lt%3B%5C%2Fi%26gt%3B%289%29%2C%20e9286.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.9286%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.9286%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Scale-dependent%20environmental%20effects%20on%20phenotypic%20distributions%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ananda%20R.%22%2C%22lastName%22%3A%22Pereira%20Martins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lucas%20P.%22%2C%22lastName%22%3A%22Martins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wing-Zheng%22%2C%22lastName%22%3A%22Ho%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22William%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonathan%20S.%22%2C%22lastName%22%3A%22Ready%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rowan%22%2C%22lastName%22%3A%22Barrett%22%7D%5D%2C%22abstractNote%22%3A%22Identifying%20the%20relative%20importance%20of%20different%20mechanisms%20responsible%20for%20the%20emergence%20and%20maintenance%20of%20phenotypic%20diversity%20can%20be%20challenging%2C%20as%20multiple%20selective%20pressures%20and%20stochastic%20events%20are%20involved%20in%20these%20processes.%20Therefore%2C%20testing%20how%20environmental%20conditions%20shape%20the%20distribution%20of%20phenotypes%20can%20offer%20important%20insights%20on%20local%20adaptation%2C%20divergence%2C%20and%20speciation.%20The%20red-yellow%20M%5Cu00fcllerian%20mimicry%20ring%20of%20Heliconius%20butterflies%20exhibits%20a%20wide%20diversity%20of%20color%20patterns%20across%20the%20Neotropics%20and%20is%20involved%20in%20multiple%20hybrid%20zones%2C%20making%20it%20a%20powerful%20system%20to%20investigate%20environmental%20drivers%20of%20phenotypic%20distributions.%20Using%20the%20distantly%20related%20Heliconius%20erato%20and%20Heliconius%20melpomene%20co-mimics%20and%20a%20multiscale%20distribution%20approach%2C%20we%20investigated%20whether%20distinct%20phenotypes%20of%20these%20species%20are%20associated%20with%20different%20environmental%20conditions.%20We%20show%20that%20Heliconius%20red-yellow%20phenotypic%20distribution%20is%20strongly%20driven%20by%20environmental%20gradients%20%28especially%20thermal%20and%20precipitation%20variables%29%2C%20but%20that%20phenotype%20and%20environment%20associations%20vary%20with%20spatial%20scale.%20While%20co-mimics%20are%20usually%20predicted%20to%20occur%20in%20similar%20environments%20at%20large%20spatial%20scales%2C%20patterns%20at%20local%20scales%20are%20not%20always%20consistent%20%28i.e.%2C%20different%20variables%20are%20best%20predictors%20of%20phenotypic%20occurrence%20in%20different%20locations%29%20or%20congruent%20%28i.e.%2C%20co-mimics%20show%20distinct%20associations%20with%20environment%29.%20We%20suggest%20that%20large-scale%20analyses%20are%20important%20for%20identifying%20how%20environmental%20factors%20shape%20broad%20mimetic%20phenotypic%20distributions%2C%20but%20that%20local%20studies%20are%20essential%20to%20understand%20the%20context-dependent%20biotic%2C%20abiotic%2C%20and%20historical%20mechanisms%20driving%20finer-scale%20phenotypic%20transitions.%22%2C%22date%22%3A%222022-09%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fece3.9286%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2236177141%22%2C%22PMCID%22%3A%22PMC9471044%22%2C%22ISSN%22%3A%222045-7758%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22M32IKLF5%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Thawornwattana%20et%20al.%22%2C%22parsedDate%22%3A%222022-08-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BThawornwattana%2C%20Y.%2C%20Seixas%2C%20F.%20A.%2C%20Yang%2C%20Z.%2C%20%26amp%3B%20Mallet%2C%20J.%20%282022%29.%20Full-Likelihood%20Genomic%20Analysis%20Clarifies%20a%20Complex%20History%20of%20Species%20Divergence%20and%20Introgression%3A%20The%20Example%20of%20the%20erato-sara%20Group%20of%20Heliconius%20Butterflies.%20%26lt%3Bi%26gt%3BSystematic%20Biology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B71%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%201159%26%23x2013%3B1177.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyac009%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fsysbio%5C%2Fsyac009%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Full-Likelihood%20Genomic%20Analysis%20Clarifies%20a%20Complex%20History%20of%20Species%20Divergence%20and%20Introgression%3A%20The%20Example%20of%20the%20erato-sara%20Group%20of%20Heliconius%20Butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yuttapong%22%2C%22lastName%22%3A%22Thawornwattana%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fernando%20A.%22%2C%22lastName%22%3A%22Seixas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ziheng%22%2C%22lastName%22%3A%22Yang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%22%2C%22lastName%22%3A%22Mallet%22%7D%5D%2C%22abstractNote%22%3A%22Introgressive%20hybridization%20plays%20a%20key%20role%20in%20adaptive%20evolution%20and%20species%20diversification%20in%20many%20groups%20of%20species.%20However%2C%20frequent%20hybridization%20and%20gene%20flow%20between%20species%20make%20estimation%20of%20the%20species%20phylogeny%20and%20key%20population%20parameters%20challenging.%20Here%2C%20we%20show%20that%20by%20accounting%20for%20phasing%20and%20using%20full-likelihood%20methods%2C%20introgression%20histories%20and%20population%20parameters%20can%20be%20estimated%20reliably%20from%20whole-genome%20sequence%20data.%20We%20employ%20the%20multispecies%20coalescent%20%28MSC%29%20model%20with%20and%20without%20gene%20flow%20to%20infer%20the%20species%20phylogeny%20and%20cross-species%20introgression%20events%20using%20genomic%20data%20from%20six%20members%20of%20the%20erato-sara%20clade%20of%20Heliconius%20butterflies.%20The%20methods%20naturally%20accommodate%20random%20fluctuations%20in%20genealogical%20history%20across%20the%20genome%20due%20to%20deep%20coalescence.%20To%20avoid%20heterozygote%20phasing%20errors%20in%20haploid%20sequences%20commonly%20produced%20by%20genome%20assembly%20methods%2C%20we%20process%20and%20compile%20unphased%20diploid%20sequence%20alignments%20and%20use%20analytical%20methods%20to%20average%20over%20uncertainties%20in%20heterozygote%20phase%20resolution.%20There%20is%20robust%20evidence%20for%20introgression%20across%20the%20genome%2C%20both%20among%20distantly%20related%20species%20deep%20in%20the%20phylogeny%20and%20between%20sister%20species%20in%20shallow%20parts%20of%20the%20tree.%20We%20obtain%20chromosome-specific%20estimates%20of%20key%20population%20parameters%20such%20as%20introgression%20directions%2C%20times%20and%20probabilities%2C%20as%20well%20as%20species%20divergence%20times%20and%20population%20sizes%20for%20modern%20and%20ancestral%20species.%20We%20confirm%20ancestral%20gene%20flow%20between%20the%20sara%20clade%20and%20an%20ancestral%20population%20of%20Heliconius%20telesiphe%2C%20a%20likely%20hybrid%20speciation%20origin%20for%20Heliconius%20hecalesia%2C%20and%20gene%20flow%20between%20the%20sister%20species%20Heliconius%20erato%20and%20Heliconius%20himera.%20Inferred%20introgression%20among%20ancestral%20species%20also%20explains%20the%20history%20of%20two%20chromosomal%20inversions%20deep%20in%20the%20phylogeny%20of%20the%20group.%20This%20study%20illustrates%20how%20a%20full-likelihood%20approach%20based%20on%20the%20MSC%20makes%20it%20possible%20to%20extract%20rich%20historical%20information%20of%20species%20divergence%20and%20gene%20flow%20from%20genomic%20data.%20%5B3s%3B%20bpp%3B%20gene%20flow%3B%20Heliconius%3B%20hybrid%20speciation%3B%20introgression%3B%20inversion%3B%20multispecies%20coalescent%5D.%22%2C%22date%22%3A%222022-08-10%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fsysbio%5C%2Fsyac009%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235169847%22%2C%22PMCID%22%3A%22PMC9366460%22%2C%22ISSN%22%3A%221076-836X%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22CH7H2GWK%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Montejo-Kovacevich%20et%20al.%22%2C%22parsedDate%22%3A%222022-08-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMontejo-Kovacevich%2C%20G.%2C%20Meier%2C%20J.%20I.%2C%20Bacquet%2C%20C.%20N.%2C%20Warren%2C%20I.%20A.%2C%20Chan%2C%20Y.%20F.%2C%20Kucka%2C%20M.%2C%20Salazar%2C%20C.%2C%20Rueda-M%2C%20N.%2C%20Montgomery%2C%20S.%20H.%2C%20McMillan%2C%20W.%20O.%2C%20Kozak%2C%20K.%20M.%2C%20Nadeau%2C%20N.%20J.%2C%20Martin%2C%20S.%20H.%2C%20%26amp%3B%20Jiggins%2C%20C.%20D.%20%282022%29.%20Repeated%20genetic%20adaptation%20to%20altitude%20in%20two%20tropical%20butterflies.%20%26lt%3Bi%26gt%3BNature%20Communications%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B13%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%204676.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-022-32316-x%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-022-32316-x%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Repeated%20genetic%20adaptation%20to%20altitude%20in%20two%20tropical%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gabriela%22%2C%22lastName%22%3A%22Montejo-Kovacevich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joana%20I.%22%2C%22lastName%22%3A%22Meier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%20N.%22%2C%22lastName%22%3A%22Bacquet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ian%20A.%22%2C%22lastName%22%3A%22Warren%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yingguang%20Frank%22%2C%22lastName%22%3A%22Chan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marek%22%2C%22lastName%22%3A%22Kucka%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camilo%22%2C%22lastName%22%3A%22Salazar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicol%22%2C%22lastName%22%3A%22Rueda-M%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Krzysztof%20M.%22%2C%22lastName%22%3A%22Kozak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicola%20J.%22%2C%22lastName%22%3A%22Nadeau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simon%20H.%22%2C%22lastName%22%3A%22Martin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%20D.%22%2C%22lastName%22%3A%22Jiggins%22%7D%5D%2C%22abstractNote%22%3A%22Repeated%20evolution%20can%20provide%20insight%20into%20the%20mechanisms%20that%20facilitate%20adaptation%20to%20novel%20or%20changing%20environments.%20Here%20we%20study%20adaptation%20to%20altitude%20in%20two%20tropical%20butterflies%2C%20Heliconius%20erato%20and%20H.%20melpomene%2C%20which%20have%20repeatedly%20and%20independently%20adapted%20to%20montane%20habitats%20on%20either%20side%20of%20the%20Andes.%20We%20sequenced%20518%20whole%20genomes%20from%20altitudinal%20transects%20and%20found%20many%20regions%20differentiated%20between%20highland%20%28~%201200%5Cu2009m%29%20and%20lowland%20%28~%20200%5Cu2009m%29%20populations.%20We%20show%20repeated%20genetic%20differentiation%20across%20replicate%20populations%20within%20species%2C%20including%20allopatric%20comparisons.%20In%20contrast%2C%20there%20is%20little%20molecular%20parallelism%20between%20the%20two%20species.%20By%20sampling%20five%20close%20relatives%2C%20we%20find%20that%20a%20large%20proportion%20of%20divergent%20regions%20identified%20within%20species%20have%20arisen%20from%20standing%20variation%20and%20putative%20adaptive%20introgression%20from%20high-altitude%20specialist%20species.%20Taken%20together%20our%20study%20supports%20a%20role%20for%20both%20standing%20genetic%20variation%20and%20gene%20flow%20from%20independently%20adapted%20species%20in%20promoting%20parallel%20local%20adaptation%20to%20the%20environment.%22%2C%22date%22%3A%222022-08-09%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-022-32316-x%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235945236%22%2C%22PMCID%22%3A%22PMC9363431%22%2C%22ISSN%22%3A%222041-1723%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22XFVR8DJL%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Jay%20et%20al.%22%2C%22parsedDate%22%3A%222022-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BJay%2C%20P.%2C%20Leroy%2C%20M.%2C%20Le%20Poul%2C%20Y.%2C%20Whibley%2C%20A.%2C%20Arias%2C%20M.%2C%20Chouteau%2C%20M.%2C%20%26amp%3B%20Joron%2C%20M.%20%282022%29.%20Association%20mapping%20of%20colour%20variation%20in%20a%20butterfly%20provides%20evidence%20that%20a%20supergene%20locks%20together%20a%20cluster%20of%20adaptive%20loci.%20%26lt%3Bi%26gt%3BPhilosophical%20Transactions%20of%20the%20Royal%20Society%20of%20London.%20Series%20B%2C%20Biological%20Sciences%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B377%26lt%3B%5C%2Fi%26gt%3B%281856%29%2C%2020210193.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frstb.2021.0193%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frstb.2021.0193%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Association%20mapping%20of%20colour%20variation%20in%20a%20butterfly%20provides%20evidence%20that%20a%20supergene%20locks%20together%20a%20cluster%20of%20adaptive%20loci%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Jay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manon%22%2C%22lastName%22%3A%22Leroy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yann%22%2C%22lastName%22%3A%22Le%20Poul%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annabel%22%2C%22lastName%22%3A%22Whibley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M%5Cu00f3nica%22%2C%22lastName%22%3A%22Arias%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mathieu%22%2C%22lastName%22%3A%22Chouteau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mathieu%22%2C%22lastName%22%3A%22Joron%22%7D%5D%2C%22abstractNote%22%3A%22Supergenes%20are%20genetic%20architectures%20associated%20with%20discrete%20and%20concerted%20variation%20in%20multiple%20traits.%20It%20has%20long%20been%20suggested%20that%20supergenes%20control%20these%20complex%20polymorphisms%20by%20suppressing%20recombination%20between%20sets%20of%20coadapted%20genes.%20However%2C%20because%20recombination%20suppression%20hinders%20the%20dissociation%20of%20the%20individual%20effects%20of%20genes%20within%20supergenes%2C%20there%20is%20still%20little%20evidence%20that%20supergenes%20evolve%20by%20tightening%20linkage%20between%20coadapted%20genes.%20Here%2C%20combining%20a%20landmark-free%20phenotyping%20algorithm%20with%20multivariate%20genome-wide%20association%20studies%2C%20we%20dissected%20the%20genetic%20basis%20of%20wing%20pattern%20variation%20in%20the%20butterfly%20Heliconius%20numata.%20We%20show%20that%20the%20supergene%20controlling%20the%20striking%20wing%20pattern%20polymorphism%20displayed%20by%20this%20species%20contains%20several%20independent%20loci%20associated%20with%20different%20features%20of%20wing%20patterns.%20The%20three%20chromosomal%20inversions%20of%20this%20supergene%20suppress%20recombination%20between%20these%20loci%2C%20supporting%20the%20hypothesis%20that%20they%20may%20have%20evolved%20because%20they%20captured%20beneficial%20combinations%20of%20alleles.%20Some%20of%20these%20loci%20are%2C%20however%2C%20associated%20with%20colour%20variations%20only%20in%20a%20subset%20of%20morphs%20where%20the%20phenotype%20is%20controlled%20by%20derived%20inversion%20forms%2C%20indicating%20that%20they%20were%20recruited%20after%20the%20formation%20of%20the%20inversions.%20Our%20study%20shows%20that%20supergenes%20and%20clusters%20of%20adaptive%20loci%20in%20general%20may%20form%20via%20the%20evolution%20of%20chromosomal%20rearrangements%20suppressing%20recombination%20between%20co-adapted%20loci%20but%20also%20via%20the%20subsequent%20recruitment%20of%20linked%20adaptive%20mutations.%20This%20article%20is%20part%20of%20the%20theme%20issue%20%26%23039%3BGenomic%20architecture%20of%20supergenes%3A%20causes%20and%20evolutionary%20consequences%26%23039%3B.%22%2C%22date%22%3A%222022-08%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1098%5C%2Frstb.2021.0193%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235694756%22%2C%22PMCID%22%3A%22PMC9189503%22%2C%22ISSN%22%3A%221471-2970%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%227U5UN7TW%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Berdan%20et%20al.%22%2C%22parsedDate%22%3A%222022-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBerdan%2C%20E.%20L.%2C%20Flatt%2C%20T.%2C%20Kozak%2C%20G.%20M.%2C%20Lotterhos%2C%20K.%20E.%2C%20%26amp%3B%20Wielstra%2C%20B.%20%282022%29.%20Genomic%20architecture%20of%20supergenes%3A%20connecting%20form%20and%20function.%20%26lt%3Bi%26gt%3BPhilosophical%20Transactions%20of%20the%20Royal%20Society%20of%20London.%20Series%20B%2C%20Biological%20Sciences%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B377%26lt%3B%5C%2Fi%26gt%3B%281856%29%2C%2020210192.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frstb.2021.0192%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frstb.2021.0192%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Genomic%20architecture%20of%20supergenes%3A%20connecting%20form%20and%20function%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emma%20L.%22%2C%22lastName%22%3A%22Berdan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Flatt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Genevieve%20M.%22%2C%22lastName%22%3A%22Kozak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katie%20E.%22%2C%22lastName%22%3A%22Lotterhos%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ben%22%2C%22lastName%22%3A%22Wielstra%22%7D%5D%2C%22abstractNote%22%3A%22Supergenes%20are%20tightly%20linked%20sets%20of%20loci%20that%20are%20inherited%20together%20and%20control%20complex%20phenotypes.%20While%20classical%20supergenes-governing%20traits%20such%20as%20wing%20patterns%20in%20Heliconius%20butterflies%20or%20heterostyly%20in%20Primula-have%20been%20studied%20since%20the%20Modern%20Synthesis%2C%20we%20still%20understand%20very%20little%20about%20how%20they%20evolve%20and%20persist%20in%20nature.%20The%20genetic%20architecture%20of%20supergenes%20is%20a%20critical%20factor%20affecting%20their%20evolutionary%20fate%2C%20as%20it%20can%20change%20key%20parameters%20such%20as%20recombination%20rate%20and%20effective%20population%20size%2C%20potentially%20redirecting%20molecular%20evolution%20of%20the%20supergene%20in%20addition%20to%20the%20surrounding%20genomic%20region.%20To%20understand%20supergene%20evolution%2C%20we%20must%20link%20genomic%20architecture%20with%20evolutionary%20patterns%20and%20processes.%20This%20is%20now%20becoming%20possible%20with%20recent%20advances%20in%20sequencing%20technology%20and%20powerful%20forward%20computer%20simulations.%20The%20present%20theme%20issue%20brings%20together%20theoretical%20and%20empirical%20papers%2C%20as%20well%20as%20opinion%20and%20synthesis%20papers%2C%20which%20showcase%20the%20architectural%20diversity%20of%20supergenes%20and%20connect%20this%20to%20critical%20processes%20in%20supergene%20evolution%2C%20such%20as%20polymorphism%20maintenance%20and%20mutation%20accumulation.%20Here%2C%20we%20summarize%20those%20insights%20to%20highlight%20new%20ideas%20and%20methods%20that%20illuminate%20the%20path%20forward%20for%20the%20study%20of%20supergenes%20in%20nature.%20This%20article%20is%20part%20of%20the%20theme%20issue%20%26%23039%3BGenomic%20architecture%20of%20supergenes%3A%20causes%20and%20evolutionary%20consequences%26%23039%3B.%22%2C%22date%22%3A%222022-08%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1098%5C%2Frstb.2021.0192%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235694757%22%2C%22PMCID%22%3A%22PMC9189501%22%2C%22ISSN%22%3A%221471-2970%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22RGYU6BV4%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Cama%20et%20al.%22%2C%22parsedDate%22%3A%222022-07-27%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCama%2C%20B.%2C%20Ehlers%2C%20S.%2C%20Szczerbowski%2C%20D.%2C%20Thomas-Oates%2C%20J.%2C%20Jiggins%2C%20C.%20D.%2C%20Schulz%2C%20S.%2C%20McMillan%2C%20W.%20O.%2C%20%26amp%3B%20Dasmahapatra%2C%20K.%20K.%20%282022%29.%20Exploitation%20of%20an%20ancestral%20pheromone%20biosynthetic%20pathway%20contributes%20to%20diversification%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BProceedings.%20Biological%20Sciences%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B289%26lt%3B%5C%2Fi%26gt%3B%281979%29%2C%2020220474.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frspb.2022.0474%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frspb.2022.0474%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Exploitation%20of%20an%20ancestral%20pheromone%20biosynthetic%20pathway%20contributes%20to%20diversification%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bruna%22%2C%22lastName%22%3A%22Cama%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Ehlers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daiane%22%2C%22lastName%22%3A%22Szczerbowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jane%22%2C%22lastName%22%3A%22Thomas-Oates%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%20D.%22%2C%22lastName%22%3A%22Jiggins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefan%22%2C%22lastName%22%3A%22Schulz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kanchon%20K.%22%2C%22lastName%22%3A%22Dasmahapatra%22%7D%5D%2C%22abstractNote%22%3A%22During%20courtship%2C%20male%20butterflies%20of%20many%20species%20produce%20androconial%20secretions%20containing%20male%20sex%20pheromones%20%28MSPs%29%20that%20communicate%20species%20identity%20and%20affect%20female%20choice.%20MSPs%20are%20thus%20likely%20candidates%20as%20reproductive%20barriers%2C%20yet%20their%20role%20in%20speciation%20remains%20poorly%20studied.%20Although%20Heliconius%20butterflies%20are%20a%20model%20system%20in%20speciation%2C%20their%20MSPs%20have%20not%20been%20investigated%20from%20a%20macroevolutionary%20perspective.%20We%20use%20GC%5C%2FMS%20to%20characterize%20male%20androconial%20secretions%20in%2033%20of%20the%2069%20species%20in%20the%20Heliconiini%20tribe.%20We%20found%20these%20blends%20to%20be%20species-specific%2C%20consistent%20with%20a%20role%20in%20reproductive%20isolation.%20We%20detected%20a%20burst%20in%20blend%20diversification%20rate%20at%20the%20most%20speciose%20genus%2C%20Heliconius%3B%20a%20consequence%20of%20Heliconius%20and%20Eueides%20species%20using%20a%20fatty%20acid%20%28FA%29%20metabolic%20pathway%20to%20unlock%20more%20complex%20blends%20than%20basal%20Heliconiini%20species%2C%20whose%20secretions%20are%20dominated%20by%20plant-like%20metabolites.%20A%20comparison%20of%2010%20sister%20species%20pairs%20demonstrates%20a%20striking%20positive%20correlation%20between%20blend%20dissimilarity%20and%20range%20overlap%2C%20consistent%20with%20character%20displacement%20or%20reinforcement%20in%20sympatry.%20These%20results%20demonstrate%20for%20the%20first%20time%20that%20MSP%20diversification%20can%20promote%20reproductive%20isolation%20across%20this%20group%20of%20butterflies%2C%20showcasing%20how%20implementation%20of%20an%20ancestral%20trait%2C%20the%20co-option%20of%20the%20FA%20metabolic%20pathway%20for%20pheromone%20production%2C%20can%20facilitate%20rapid%20speciation.%22%2C%22date%22%3A%222022-07-27%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1098%5C%2Frspb.2022.0474%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235892212%22%2C%22PMCID%22%3A%22PMC9326301%22%2C%22ISSN%22%3A%221471-2954%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%224T5GY6L4%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Brien%20et%20al.%22%2C%22parsedDate%22%3A%222022-07-18%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBrien%2C%20M.%20N.%2C%20Enciso-Romero%2C%20J.%2C%20Lloyd%2C%20V.%20J.%2C%20Curran%2C%20E.%20V.%2C%20Parnell%2C%20A.%20J.%2C%20Morochz%2C%20C.%2C%20Salazar%2C%20P.%20A.%2C%20Rastas%2C%20P.%2C%20Zinn%2C%20T.%2C%20%26amp%3B%20Nadeau%2C%20N.%20J.%20%282022%29.%20The%20genetic%20basis%20of%20structural%20colour%20variation%20in%20mimetic%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BPhilosophical%20Transactions%20of%20the%20Royal%20Society%20of%20London.%20Series%20B%2C%20Biological%20Sciences%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B377%26lt%3B%5C%2Fi%26gt%3B%281855%29%2C%2020200505.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frstb.2020.0505%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1098%5C%2Frstb.2020.0505%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20genetic%20basis%20of%20structural%20colour%20variation%20in%20mimetic%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%20N.%22%2C%22lastName%22%3A%22Brien%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juan%22%2C%22lastName%22%3A%22Enciso-Romero%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Victoria%20J.%22%2C%22lastName%22%3A%22Lloyd%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emma%20V.%22%2C%22lastName%22%3A%22Curran%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrew%20J.%22%2C%22lastName%22%3A%22Parnell%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carlos%22%2C%22lastName%22%3A%22Morochz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patricio%20A.%22%2C%22lastName%22%3A%22Salazar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pasi%22%2C%22lastName%22%3A%22Rastas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Zinn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicola%20J.%22%2C%22lastName%22%3A%22Nadeau%22%7D%5D%2C%22abstractNote%22%3A%22Structural%20colours%2C%20produced%20by%20the%20reflection%20of%20light%20from%20ultrastructures%2C%20have%20evolved%20multiple%20times%20in%20butterflies.%20Unlike%20pigmentary%20colours%20and%20patterns%2C%20little%20is%20known%20about%20the%20genetic%20basis%20of%20these%20colours.%20Reflective%20structures%20on%20wing-scale%20ridges%20are%20responsible%20for%20iridescent%20structural%20colour%20in%20many%20butterflies%2C%20including%20the%20M%5Cu00fcllerian%20mimics%20Heliconius%20erato%20and%20Heliconius%20melpomene.%20Here%2C%20we%20quantify%20aspects%20of%20scale%20ultrastructure%20variation%20and%20colour%20in%20crosses%20between%20iridescent%20and%20non-iridescent%20subspecies%20of%20both%20of%20these%20species%20and%20perform%20quantitative%20trait%20locus%20%28QTL%29%20mapping.%20We%20show%20that%20iridescent%20structural%20colour%20has%20a%20complex%20genetic%20basis%20in%20both%20species%2C%20with%20offspring%20from%20crosses%20having%20a%20wide%20variation%20in%20blue%20colour%20%28both%20hue%20and%20brightness%29%20and%20scale%20structure%20measurements.%20We%20detect%20two%20different%20genomic%20regions%20in%20each%20species%20that%20explain%20modest%20amounts%20of%20this%20variation%2C%20with%20a%20sex-linked%20QTL%20in%20H.%20erato%20but%20not%20H.%20melpomene.%20We%20also%20find%20differences%20between%20species%20in%20the%20relationships%20between%20structure%20and%20colour%2C%20overall%20suggesting%20that%20these%20species%20have%20followed%20different%20evolutionary%20trajectories%20in%20their%20evolution%20of%20structural%20colour.%20We%20then%20identify%20genes%20within%20the%20QTL%20intervals%20that%20are%20differentially%20expressed%20between%20subspecies%20and%5C%2For%20wing%20regions%2C%20revealing%20likely%20candidates%20for%20genes%20controlling%20structural%20colour%20formation.%20This%20article%20is%20part%20of%20the%20theme%20issue%20%26%23039%3BGenetic%20basis%20of%20adaptation%20and%20speciation%3A%20from%20loci%20to%20causative%20mutations%26%23039%3B.%22%2C%22date%22%3A%222022-07-18%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1098%5C%2Frstb.2020.0505%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235634924%22%2C%22PMCID%22%3A%22PMC9149798%22%2C%22ISSN%22%3A%221471-2970%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22YKY4KA4R%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Mattila%20et%20al.%22%2C%22parsedDate%22%3A%222022-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMattila%2C%20A.%20L.%20K.%2C%20Jiggins%2C%20C.%20D.%2C%20%26amp%3B%20Saastamoinen%2C%20M.%20%282022%29.%20Condition%20dependence%20in%20biosynthesized%20chemical%20defenses%20of%20an%20aposematic%20and%20mimetic%20Heliconius%20butterfly.%20%26lt%3Bi%26gt%3BEcology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B12%26lt%3B%5C%2Fi%26gt%3B%286%29%2C%20e9041.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.9041%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.9041%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Condition%20dependence%20in%20biosynthesized%20chemical%20defenses%20of%20an%20aposematic%20and%20mimetic%20Heliconius%20butterfly%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anniina%20L.%20K.%22%2C%22lastName%22%3A%22Mattila%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%20D.%22%2C%22lastName%22%3A%22Jiggins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marjo%22%2C%22lastName%22%3A%22Saastamoinen%22%7D%5D%2C%22abstractNote%22%3A%22Aposematic%20animals%20advertise%20their%20toxicity%20or%20unpalatability%20with%20bright%20warning%20coloration.%20However%2C%20acquiring%20and%20maintaining%20chemical%20defenses%20can%20be%20energetically%20costly%2C%20and%20consequent%20associations%20with%20other%20important%20traits%20could%20shape%20chemical%20defense%20evolution.%20Here%2C%20we%20have%20tested%20whether%20chemical%20defenses%20are%20involved%20in%20energetic%20trade-offs%20with%20other%20traits%2C%20or%20whether%20the%20levels%20of%20chemical%20defenses%20are%20condition%20dependent%2C%20by%20studying%20associations%20between%20biosynthesized%20cyanogenic%20toxicity%20and%20a%20suite%20of%20key%20life-history%20and%20fitness%20traits%20in%20a%20Heliconius%20butterfly%20under%20a%20controlled%20laboratory%20setting.%20Heliconius%20butterflies%20are%20well%20known%20for%20the%20diversity%20of%20their%20warning%20color%20patterns%20and%20widespread%20mimicry%20and%20can%20both%20sequester%20the%20cyanogenic%20glucosides%20of%20their%20Passiflora%20host%20plants%20and%20biosynthesize%20these%20toxins%20de%20novo.%20We%20find%20energetically%20costly%20life-history%20traits%20to%20be%20either%20unassociated%20or%20to%20show%20a%20general%20positive%20association%20with%20biosynthesized%20cyanogenic%20toxicity.%20More%20toxic%20individuals%20developed%20faster%20and%20had%20higher%20mass%20as%20adults%20and%20a%20tendency%20for%20increased%20lifespan%20and%20fecundity.%20These%20results%20thus%20indicate%20that%20toxicity%20level%20of%20adult%20butterflies%20may%20be%20dependent%20on%20individual%20condition%2C%20influenced%20by%20genetic%20background%20or%20earlier%20conditions%2C%20with%20maternal%20effects%20as%20one%20strong%20candidate%20mechanism.%20Additionally%2C%20toxicity%20was%20higher%20in%20older%20individuals%2C%20consistent%20with%20previous%20studies%20indicating%20accumulation%20of%20toxins%20with%20age.%20As%20toxicity%20level%20at%20death%20was%20independent%20of%20lifespan%2C%20cyanogenic%20glucoside%20compounds%20may%20have%20been%20recycled%20to%20release%20resources%20relevant%20for%20longevity%20in%20these%20long-living%20butterflies.%20Understanding%20the%20origins%20and%20maintenance%20of%20variation%20in%20defenses%20is%20necessary%20in%20building%20a%20more%20complete%20picture%20of%20factors%20shaping%20the%20evolution%20of%20aposematic%20and%20mimetic%20systems.%22%2C%22date%22%3A%222022-07%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fece3.9041%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235784031%22%2C%22PMCID%22%3A%22PMC9227709%22%2C%22ISSN%22%3A%222045-7758%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22W84BWL8V%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Hebberecht%20et%20al.%22%2C%22parsedDate%22%3A%222022-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHebberecht%2C%20L.%2C%20Melo-Fl%26%23xF3%3Brez%2C%20L.%2C%20Young%2C%20F.%20J.%2C%20McMillan%2C%20W.%20O.%2C%20%26amp%3B%20Montgomery%2C%20S.%20H.%20%282022%29.%20The%20evolution%20of%20adult%20pollen%20feeding%20did%20not%20alter%20postembryonic%20growth%20in%20Heliconius%20butterflies.%20%26lt%3Bi%26gt%3BEcology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B12%26lt%3B%5C%2Fi%26gt%3B%286%29%2C%20e8999.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.8999%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.8999%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20evolution%20of%20adult%20pollen%20feeding%20did%20not%20alter%20postembryonic%20growth%20in%20Heliconius%20butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Hebberecht%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lina%22%2C%22lastName%22%3A%22Melo-Fl%5Cu00f3rez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fletcher%20J.%22%2C%22lastName%22%3A%22Young%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%5D%2C%22abstractNote%22%3A%22For%20many%20animals%2C%20the%20availability%20and%20provision%20of%20dietary%20resources%20can%20vary%20markedly%20between%20juvenile%20and%20adult%20stages%2C%20often%20leading%20to%20a%20temporal%20separation%20of%20nutrient%20acquisition%20and%20use.%20Juvenile%20developmental%20programs%20are%20likely%20limited%20by%20the%20energetic%20demands%20of%20many%20adult%20tissues%20and%20processes%20with%20early%20developmental%20origins.%20Enhanced%20dietary%20quality%20in%20the%20adult%20stage%20may%2C%20therefore%2C%20alter%20selection%20on%20life%20history%20and%20growth%20patterns%20in%20juvenile%20stages.%20Heliconius%20are%20unique%20among%20butterflies%20in%20actively%20collecting%20and%20digesting%20pollen%20grains%2C%20which%20provide%20an%20adult%20source%20of%20essential%20amino%20acids.%20The%20origin%20of%20pollen%20feeding%20has%20therefore%20previously%20been%20hypothesized%20to%20lift%20constraints%20on%20larval%20growth%20rates%2C%20allowing%20Heliconius%20to%20spend%20less%20time%20as%20larvae%20when%20they%20are%20most%20vulnerable%20to%20predation.%20By%20measuring%20larval%20and%20pupal%20life-history%20traits%20across%20three%20pollen-feeding%20and%20three%20nonpollen-feeding%20Heliconiini%2C%20we%20provide%20the%20first%20test%20of%20this%20hypothesis.%20Although%20we%20detect%20significant%20interspecific%20variation%20in%20larval%20and%20pupal%20development%2C%20we%20do%20not%20find%20any%20consistent%20shift%20associated%20with%20pollen%20feeding.%20We%20discuss%20how%20this%20result%20may%20fit%20with%20patterns%20of%20nitrogen%20allocation%2C%20the%20benefits%20of%20nitrogenous%20stores%2C%20and%20developmental%20limitations%20on%20growth.%20Our%20results%20provide%20a%20framework%20for%20studies%20aiming%20to%20link%20innovations%20in%20adult%20Heliconius%20to%20altered%20selection%20regimes%20and%20developmental%20programs%20in%20early%20life%20stages.%22%2C%22date%22%3A%222022-07%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fece3.8999%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235784071%22%2C%22PMCID%22%3A%22PMC9237422%22%2C%22ISSN%22%3A%222045-7758%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%2273RL3B5D%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Melo%20et%20al.%22%2C%22parsedDate%22%3A%222022-06-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMelo%2C%20D.%20J.%2C%20Borges%2C%20E.%20O.%2C%20Szczerbowski%2C%20D.%2C%20Vidal%2C%20D.%20M.%2C%20Schulz%2C%20S.%2C%20%26amp%3B%20Zarbin%2C%20P.%20H.%20G.%20%282022%29.%20Identification%20and%20Synthesis%20of%20a%20Macrolide%20as%20an%20Anti-aphrodisiac%20Pheromone%20from%20Males%20of%20Heliconius%20erato%20phyllis.%20%26lt%3Bi%26gt%3BOrganic%20Letters%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B24%26lt%3B%5C%2Fi%26gt%3B%2821%29%2C%203772%26%23x2013%3B3775.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Facs.orglett.2c01160%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Facs.orglett.2c01160%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Identification%20and%20Synthesis%20of%20a%20Macrolide%20as%20an%20Anti-aphrodisiac%20Pheromone%20from%20Males%20of%20Heliconius%20erato%20phyllis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Douglas%20J.%22%2C%22lastName%22%3A%22Melo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eliane%20O.%22%2C%22lastName%22%3A%22Borges%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daiane%22%2C%22lastName%22%3A%22Szczerbowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diogo%20M.%22%2C%22lastName%22%3A%22Vidal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefan%22%2C%22lastName%22%3A%22Schulz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paulo%20H.%20G.%22%2C%22lastName%22%3A%22Zarbin%22%7D%5D%2C%22abstractNote%22%3A%22Investigation%20of%20the%20contents%20of%20the%20scent%20glands%20of%20the%20heliconiine%20butterfly%20Heliconius%20erato%20phyllis%20via%20gas%20chromatography%5C%2Felectroantennography%20revealed%20an%20unprecedented%20active%20compound.%20The%20males%20transfer%20this%20compound%20to%20females%20during%20mating.%20The%20structure%20of%20%282R%2C6E%2C10R%29-2%2C6-dimethyl-6-undecen-10-olide%2C%20a%20derivative%20of%20geranylacetone%2C%20was%20proposed%20on%20the%20basis%20of%20infrared%20and%20mass%20spectrometry%20spectra%20and%20microderivatization%20and%20confirmed%20by%20racemic%20and%20stereoselective%20syntheses.%20Bioassays%20with%20the%20synthetic%20macrolide%20showed%20the%20repellency%20of%20this%20compound%2C%20termed%20phyllisolide%2C%20when%20applied%20to%20scent%20glands%20of%20females%2C%20identifying%20it%20as%20an%20anti-aphrodisiac%20pheromone.%22%2C%22date%22%3A%222022-06-03%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1021%5C%2Facs.orglett.2c01160%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235609879%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221523-7052%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22CKDGALX6%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Szczerbowski%20et%20al.%22%2C%22parsedDate%22%3A%222022-05-27%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BSzczerbowski%2C%20D.%2C%20Ehlers%2C%20S.%2C%20Darragh%2C%20K.%2C%20Jiggins%2C%20C.%2C%20%26amp%3B%20Schulz%2C%20S.%20%282022%29.%20Head%20and%20Tail%20Oxidized%20Terpenoid%20Esters%20from%20Androconia%20of%20Heliconius%20erato%20Butterflies.%20%26lt%3Bi%26gt%3BJournal%20of%20Natural%20Products%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B85%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%201428%26%23x2013%3B1435.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Facs.jnatprod.2c00300%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1021%5C%2Facs.jnatprod.2c00300%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Head%20and%20Tail%20Oxidized%20Terpenoid%20Esters%20from%20Androconia%20of%20Heliconius%20erato%20Butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daiane%22%2C%22lastName%22%3A%22Szczerbowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Ehlers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathy%22%2C%22lastName%22%3A%22Darragh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%22%2C%22lastName%22%3A%22Jiggins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefan%22%2C%22lastName%22%3A%22Schulz%22%7D%5D%2C%22abstractNote%22%3A%22Heliconius%20erato%20is%20a%20neotropical%20butterfly%20species%20that%20is%20part%20of%20a%20complex%20mimicry%20ring%2C%20with%20colorful%20wing%20patterns.%20For%20intraspecific%20communication%2C%20males%20use%20pheromones%20that%20are%20released%20from%20two%20different%20scent-emitting%20structures.%20Scent%20glands%20located%20near%20the%20abdominal%20claspers%20of%20males%2C%20containing%20antiaphrodisiac%20pheromones%2C%20release%20a%20highly%20complex%20mixture%20of%20compounds%20that%20is%20transferred%20to%20females%20during%20mating%2C%20rendering%20them%20unattractive%20to%20other%20males.%20On%20the%20other%20hand%2C%20androconia%2C%20scent-emitting%20scale%20areas%20on%20the%20wings%20of%20male%20butterflies%2C%20release%20a%20structurally%20more%20restricted%20set%20of%20compounds%20that%20likely%20serves%20an%20aphrodisiac%20role.%20We%20report%20here%20on%20two%20structurally%20related%20compounds%20that%20are%20the%20major%20androconial%20constituents%2C%20produced%20in%20high%20amounts%20and%20are%20not%20volatile%20due%20to%20their%20high%20molecular%20mass.%20Their%20structures%20were%20established%20by%20extensive%20analysis%20of%20mass%2C%20infrared%2C%20and%20NMR%20spectra%2C%20as%20well%20as%20microderivatization%20reactions%20of%20the%20natural%20extract.%20After%20establishing%20synthetic%20access%2C%20the%20compounds%20were%20unequivocally%20identified%20as%20two%20unusual%20head%20and%20tail%20oxidized%20terpenoids%2C%20%284E%2C8E%2C12E%29-4%2C8%2C12-trimethyl-16-oxoheptadeca-4%2C8%2C12-trien-1-yl%20oleate%20%281%29%20and%20stearate%20%282%29.%20Although%20behavioral%20assays%20are%20necessary%20to%20fully%20comprehend%20their%20role%20in%20the%20chemical%20communication%20of%20the%20species%2C%20hypotheses%20for%20their%20use%20by%20the%20butterflies%20are%20also%20discussed.%22%2C%22date%22%3A%222022-05-27%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1021%5C%2Facs.jnatprod.2c00300%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235587731%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221520-6025%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A33%3A28Z%22%7D%7D%2C%7B%22key%22%3A%225VCVYPKF%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Jay%20and%20Joron%22%2C%22parsedDate%22%3A%222022-05-11%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BJay%2C%20P.%2C%20%26amp%3B%20Joron%2C%20M.%20%282022%29.%20The%20double%20game%20of%20chromosomal%20inversions%20in%20a%20neotropical%20butterfly.%20%26lt%3Bi%26gt%3BComptes%20Rendus%20Biologies%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B345%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%2057%26%23x2013%3B73.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.5802%5C%2Fcrbiol.73%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.5802%5C%2Fcrbiol.73%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20double%20game%20of%20chromosomal%20inversions%20in%20a%20neotropical%20butterfly%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Jay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mathieu%22%2C%22lastName%22%3A%22Joron%22%7D%5D%2C%22abstractNote%22%3A%22Over%20a%20century%20after%20the%20first%20description%20of%20a%20polymorphism%20controlled%20by%20a%20supergene%2C%20these%20genetic%20architectures%20still%20puzzle%20biologists.%20Supergenes%20are%20groups%20of%20tightly%20linked%20loci%20facilitating%20the%20co-segregation%20of%20combinations%20of%20alleles%20underlying%20alternative%2C%20complex%20adaptive%20strategies.%20The%20suppression%20of%20recombination%20at%20supergenes%20is%20generally%20caused%20by%20polymorphic%20chromosomal%20rearrangements%2C%20such%20as%20inversions.%20The%20existence%20of%20inversion%20polymorphisms%20and%20supergene%20raises%20theoretical%20and%20empirical%20questions.%20Why%20do%20these%20architectures%20evolve%3F%20How%20can%20alternative%20combinations%20of%20alleles%20be%20formed%3F%20How%20and%20why%20is%20polymorphism%20maintained%3F%20The%20purpose%20of%20this%20paper%20is%20to%20provide%20answers%20to%20these%20questions%20by%20reviewing%20recent%20advances%20in%20the%20study%20of%20Heliconius%20numata%2C%20an%20Amazonian%20butterfly%20displaying%20a%20striking%20diversity%20of%20wing%20color%20patterns.%20In%20a%20broad%20context%2C%20this%20review%20highlights%20mechanisms%20that%20play%20an%20important%20role%20in%20the%20evolution%20of%20new%20genomic%20architecture%20and%20in%20the%20adaptation%20of%20species.%22%2C%22date%22%3A%222022-05-11%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.5802%5C%2Fcrbiol.73%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235787620%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221768-3238%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%229AMHYL4S%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Ferrari%20et%20al.%22%2C%22parsedDate%22%3A%222022-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BFerrari%2C%20G.%2C%20Atmore%2C%20L.%20M.%2C%20Jentoft%2C%20S.%2C%20Jakobsen%2C%20K.%20S.%2C%20Makowiecki%2C%20D.%2C%20Barrett%2C%20J.%20H.%2C%20%26amp%3B%20Star%2C%20B.%20%282022%29.%20An%20accurate%20assignment%20test%20for%20extremely%20low-coverage%20whole-genome%20sequence%20data.%20%26lt%3Bi%26gt%3BMolecular%20Ecology%20Resources%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B22%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%201330%26%23x2013%3B1344.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1755-0998.13551%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1755-0998.13551%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22An%20accurate%20assignment%20test%20for%20extremely%20low-coverage%20whole-genome%20sequence%20data%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Giada%22%2C%22lastName%22%3A%22Ferrari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lane%20M.%22%2C%22lastName%22%3A%22Atmore%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sissel%22%2C%22lastName%22%3A%22Jentoft%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kjetill%20S.%22%2C%22lastName%22%3A%22Jakobsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Makowiecki%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20H.%22%2C%22lastName%22%3A%22Barrett%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bastiaan%22%2C%22lastName%22%3A%22Star%22%7D%5D%2C%22abstractNote%22%3A%22Genomic%20assignment%20tests%20can%20provide%20important%20diagnostic%20biological%20characteristics%2C%20such%20as%20population%20of%20origin%20or%20ecotype.%20Yet%2C%20assignment%20tests%20often%20rely%20on%20moderate-%20to%20high-coverage%20sequence%20data%20that%20can%20be%20difficult%20to%20obtain%20for%20fields%20such%20as%20molecular%20ecology%20and%20ancient%20DNA.%20We%20have%20developed%20a%20novel%20approach%20that%20efficiently%20assigns%20biologically%20relevant%20information%20%28i.e.%2C%20population%20identity%20or%20structural%20variants%20such%20as%20inversions%29%20in%20extremely%20low-coverage%20sequence%20data.%20First%2C%20we%20generate%20databases%20from%20existing%20reference%20data%20using%20a%20subset%20of%20diagnostic%20single%20nucleotide%20polymorphisms%20%28SNPs%29%20associated%20with%20a%20biological%20characteristic.%20Low-coverage%20alignment%20files%20are%20subsequently%20compared%20to%20these%20databases%20to%20ascertain%20allelic%20state%2C%20yielding%20a%20joint%20probability%20for%20each%20association.%20To%20assess%20the%20efficacy%20of%20this%20approach%2C%20we%20assigned%20haplotypes%20and%20population%20identity%20in%20Heliconius%20butterflies%2C%20Atlantic%20herring%2C%20and%20Atlantic%20cod%20using%20chromosomal%20inversion%20sites%20and%20whole-genome%20data.%20We%20scored%20both%20modern%20and%20ancient%20specimens%2C%20including%20the%20first%20whole-genome%20sequence%20data%20recovered%20from%20ancient%20Atlantic%20herring%20bones.%20The%20method%20accurately%20assigns%20biological%20characteristics%2C%20including%20population%20membership%2C%20using%20extremely%20low-coverage%20data%20%28as%20low%20as%200.0001x%29%20based%20on%20genome-wide%20SNPs.%20This%20approach%20will%20therefore%20increase%20the%20number%20of%20samples%20in%20evolutionary%2C%20ecological%20and%20archaeological%20research%20for%20which%20relevant%20biological%20information%20can%20be%20obtained.%22%2C%22date%22%3A%222022-05%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2F1755-0998.13551%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2234779123%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221755-0998%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22K37RUSQX%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22McCulloch%20et%20al.%22%2C%22parsedDate%22%3A%222022-04-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMcCulloch%2C%20K.%20J.%2C%20Macias-Mu%26%23xF1%3Boz%2C%20A.%2C%20Mortazavi%2C%20A.%2C%20%26amp%3B%20Briscoe%2C%20A.%20D.%20%282022%29.%20Multiple%20Mechanisms%20of%20Photoreceptor%20Spectral%20Tuning%20in%20Heliconius%20Butterflies.%20%26lt%3Bi%26gt%3BMolecular%20Biology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B39%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20msac067.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsac067%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsac067%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Multiple%20Mechanisms%20of%20Photoreceptor%20Spectral%20Tuning%20in%20Heliconius%20Butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kyle%20J.%22%2C%22lastName%22%3A%22McCulloch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aide%22%2C%22lastName%22%3A%22Macias-Mu%5Cu00f1oz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ali%22%2C%22lastName%22%3A%22Mortazavi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adriana%20D.%22%2C%22lastName%22%3A%22Briscoe%22%7D%5D%2C%22abstractNote%22%3A%22The%20evolution%20of%20color%20vision%20is%20often%20studied%20through%20the%20lens%20of%20receptor%20gain%20relative%20to%20an%20ancestor%20with%20fewer%20spectral%20classes%20of%20photoreceptor.%20For%20instance%2C%20in%20Heliconius%20butterflies%2C%20a%20genus-specific%20UVRh%20opsin%20duplication%20led%20to%20the%20evolution%20of%20UV%20color%20discrimination%20in%20Heliconius%20erato%20females%2C%20a%20rare%20trait%20among%20butterflies.%20However%2C%20color%20vision%20evolution%20is%20not%20well%20understood%20in%20the%20context%20of%20loss.%20In%20Heliconius%20melpomene%20and%20Heliconius%20ismenius%20lineages%2C%20the%20UV2%20receptor%20subtype%20has%20been%20lost%2C%20which%20limits%20female%20color%20vision%20in%20shorter%20wavelengths.%20Here%2C%20we%20compare%20the%20visual%20systems%20of%20butterflies%20that%20have%20either%20retained%20or%20lost%20the%20UV2%20photoreceptor%20using%20intracellular%20recordings%2C%20ATAC-seq%2C%20and%20antibody%20staining.%20We%20identify%20several%20ways%20these%20butterflies%20modulate%20their%20color%20vision.%20In%20H.%20melpomene%2C%20chromatin%20reorganization%20has%20downregulated%20an%20otherwise%20intact%20UVRh2%20gene%2C%20whereas%20in%20H.%20ismenius%2C%20pseudogenization%20has%20led%20to%20the%20truncation%20of%20UVRh2.%20In%20species%20that%20lack%20the%20UV2%20receptor%2C%20the%20peak%20sensitivity%20of%20the%20remaining%20UV1%20photoreceptor%20cell%20is%20shifted%20to%20longer%20wavelengths.%20Across%20Heliconius%2C%20we%20identify%20the%20widespread%20use%20of%20filtering%20pigments%20and%20co-expression%20of%20two%20opsins%20in%20the%20same%20photoreceptor%20cells.%20Multiple%20mechanisms%20of%20spectral%20tuning%2C%20including%20the%20molecular%20evolution%20of%20blue%20opsins%2C%20have%20led%20to%20the%20divergence%20of%20receptor%20sensitivities%20between%20species.%20The%20diversity%20of%20photoreceptor%20and%20ommatidial%20subtypes%20between%20species%20suggests%20that%20Heliconius%20visual%20systems%20are%20under%20varying%20selection%20pressures%20for%20color%20discrimination.%20Modulating%20the%20wavelengths%20of%20peak%20sensitivities%20of%20both%20the%20blue-%20and%20remaining%20UV-sensitive%20photoreceptor%20cells%20suggests%20that%20Heliconius%20species%20may%20have%20compensated%20for%20UV%20receptor%20loss.%22%2C%22date%22%3A%222022-04-10%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fmolbev%5C%2Fmsac067%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235348742%22%2C%22PMCID%22%3A%22PMC9048915%22%2C%22ISSN%22%3A%221537-1719%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A33%3A28Z%22%7D%7D%2C%7B%22key%22%3A%22E49XX4LE%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22McCulloch%20et%20al.%22%2C%22parsedDate%22%3A%222022-04-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMcCulloch%2C%20K.%20J.%2C%20Macias-Mu%26%23xF1%3Boz%2C%20A.%2C%20Mortazavi%2C%20A.%2C%20%26amp%3B%20Briscoe%2C%20A.%20D.%20%282022%29.%20Multiple%20Mechanisms%20of%20Photoreceptor%20Spectral%20Tuning%20in%20Heliconius%20Butterflies.%20%26lt%3Bi%26gt%3BMolecular%20Biology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B39%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20msac067.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsac067%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fmolbev%5C%2Fmsac067%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Multiple%20Mechanisms%20of%20Photoreceptor%20Spectral%20Tuning%20in%20Heliconius%20Butterflies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kyle%20J.%22%2C%22lastName%22%3A%22McCulloch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aide%22%2C%22lastName%22%3A%22Macias-Mu%5Cu00f1oz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ali%22%2C%22lastName%22%3A%22Mortazavi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adriana%20D.%22%2C%22lastName%22%3A%22Briscoe%22%7D%5D%2C%22abstractNote%22%3A%22The%20evolution%20of%20color%20vision%20is%20often%20studied%20through%20the%20lens%20of%20receptor%20gain%20relative%20to%20an%20ancestor%20with%20fewer%20spectral%20classes%20of%20photoreceptor.%20For%20instance%2C%20in%20Heliconius%20butterflies%2C%20a%20genus-specific%20UVRh%20opsin%20duplication%20led%20to%20the%20evolution%20of%20UV%20color%20discrimination%20in%20Heliconius%20erato%20females%2C%20a%20rare%20trait%20among%20butterflies.%20However%2C%20color%20vision%20evolution%20is%20not%20well%20understood%20in%20the%20context%20of%20loss.%20In%20Heliconius%20melpomene%20and%20Heliconius%20ismenius%20lineages%2C%20the%20UV2%20receptor%20subtype%20has%20been%20lost%2C%20which%20limits%20female%20color%20vision%20in%20shorter%20wavelengths.%20Here%2C%20we%20compare%20the%20visual%20systems%20of%20butterflies%20that%20have%20either%20retained%20or%20lost%20the%20UV2%20photoreceptor%20using%20intracellular%20recordings%2C%20ATAC-seq%2C%20and%20antibody%20staining.%20We%20identify%20several%20ways%20these%20butterflies%20modulate%20their%20color%20vision.%20In%20H.%20melpomene%2C%20chromatin%20reorganization%20has%20downregulated%20an%20otherwise%20intact%20UVRh2%20gene%2C%20whereas%20in%20H.%20ismenius%2C%20pseudogenization%20has%20led%20to%20the%20truncation%20of%20UVRh2.%20In%20species%20that%20lack%20the%20UV2%20receptor%2C%20the%20peak%20sensitivity%20of%20the%20remaining%20UV1%20photoreceptor%20cell%20is%20shifted%20to%20longer%20wavelengths.%20Across%20Heliconius%2C%20we%20identify%20the%20widespread%20use%20of%20filtering%20pigments%20and%20co-expression%20of%20two%20opsins%20in%20the%20same%20photoreceptor%20cells.%20Multiple%20mechanisms%20of%20spectral%20tuning%2C%20including%20the%20molecular%20evolution%20of%20blue%20opsins%2C%20have%20led%20to%20the%20divergence%20of%20receptor%20sensitivities%20between%20species.%20The%20diversity%20of%20photoreceptor%20and%20ommatidial%20subtypes%20between%20species%20suggests%20that%20Heliconius%20visual%20systems%20are%20under%20varying%20selection%20pressures%20for%20color%20discrimination.%20Modulating%20the%20wavelengths%20of%20peak%20sensitivities%20of%20both%20the%20blue-%20and%20remaining%20UV-sensitive%20photoreceptor%20cells%20suggests%20that%20Heliconius%20species%20may%20have%20compensated%20for%20UV%20receptor%20loss.%22%2C%22date%22%3A%222022-04-10%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fmolbev%5C%2Fmsac067%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235348742%22%2C%22PMCID%22%3A%22PMC9048915%22%2C%22ISSN%22%3A%221537-1719%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22JG5SZ46D%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Hanly%20et%20al.%22%2C%22parsedDate%22%3A%222022-04-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHanly%2C%20J.%20J.%2C%20Livraghi%2C%20L.%2C%20Heryanto%2C%20C.%2C%20McMillan%2C%20W.%20O.%2C%20Jiggins%2C%20C.%20D.%2C%20Gilbert%2C%20L.%20E.%2C%20%26amp%3B%20Martin%2C%20A.%20%282022%29.%20A%20large%20deletion%20at%20the%20cortex%20locus%20eliminates%20butterfly%20wing%20patterning.%20%26lt%3Bi%26gt%3BG3%20%28Bethesda%2C%20Md.%29%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B12%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20jkac021.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fg3journal%5C%2Fjkac021%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fg3journal%5C%2Fjkac021%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22A%20large%20deletion%20at%20the%20cortex%20locus%20eliminates%20butterfly%20wing%20patterning%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joseph%20J.%22%2C%22lastName%22%3A%22Hanly%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Luca%22%2C%22lastName%22%3A%22Livraghi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christa%22%2C%22lastName%22%3A%22Heryanto%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%20D.%22%2C%22lastName%22%3A%22Jiggins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lawrence%20E.%22%2C%22lastName%22%3A%22Gilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arnaud%22%2C%22lastName%22%3A%22Martin%22%7D%5D%2C%22abstractNote%22%3A%22As%20the%20genetic%20basis%20of%20natural%20and%20domesticated%20variation%20has%20been%20described%20in%20recent%20years%2C%20a%20number%20of%20hotspot%20genes%20have%20been%20repeatedly%20identified%20as%20the%20targets%20of%20selection%2C%20Heliconius%20butterflies%20display%20a%20spectacular%20diversity%20of%20pattern%20variants%20in%20the%20wild%20and%20the%20genetic%20basis%20of%20these%20patterns%20has%20been%20well-described.%20Here%2C%20we%20sought%20to%20identify%20the%20mechanism%20behind%20an%20unusual%20pattern%20variant%20that%20is%20instead%20found%20in%20captivity%2C%20the%20ivory%20mutant%2C%20in%20which%20all%20scales%20on%20both%20the%20wings%20and%20body%20become%20white%20or%20yellow.%20Using%20a%20combination%20of%20autozygosity%20mapping%20and%20coverage%20analysis%20from%2037%20captive%20individuals%2C%20we%20identify%20a%2078-kb%20deletion%20at%20the%20cortex%20wing%20patterning%20locus%2C%20a%20gene%20which%20has%20been%20associated%20with%20wing%20pattern%20evolution%20in%20H.%20melpomene%20and%2010%20divergent%20lepidopteran%20species.%20This%20deletion%20is%20undetected%20among%20458%20wild%20Heliconius%20genomes%20samples%2C%20and%20its%20dosage%20explains%20both%20homozygous%20and%20heterozygous%20ivory%20phenotypes%20found%20in%20captivity.%20The%20deletion%20spans%20a%20large%205%26%23039%3B%20region%20of%20the%20cortex%20gene%20that%20includes%20a%20facultative%205%26%23039%3BUTR%20exon%20detected%20in%20larval%20wing%20disk%20transcriptomes.%20CRISPR%20mutagenesis%20of%20this%20exon%20replicates%20the%20wing%20phenotypes%20from%20coding%20knock-outs%20of%20cortex%2C%20consistent%20with%20a%20functional%20role%20of%20ivory-deleted%20elements%20in%20establishing%20scale%20color%20fate.%20Population%20demographics%20reveal%20that%20the%20stock%20giving%20rise%20to%20the%20ivory%20mutant%20has%20a%20mixed%20origin%20from%20across%20the%20wild%20range%20of%20H.%20melpomene%2C%20and%20supports%20a%20scenario%20where%20the%20ivory%20mutation%20occurred%20after%20the%20introduction%20of%20cortex%20haplotypes%20from%20Ecuador.%20Homozygotes%20for%20the%20ivory%20deletion%20are%20inviable%20while%20heterozygotes%20are%20the%20targets%20of%20artificial%20selection%2C%20joining%2040%20other%20examples%20of%20allelic%20variants%20that%20provide%20heterozygous%20advantage%20in%20animal%20populations%20under%20artificial%20selection%20by%20fanciers%20and%20breeders.%20Finally%2C%20our%20results%20highlight%20the%20promise%20of%20autozygosity%20and%20association%20mapping%20for%20identifying%20the%20genetic%20basis%20of%20aberrant%20mutations%20in%20captive%20insect%20populations.%22%2C%22date%22%3A%222022-04-04%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fg3journal%5C%2Fjkac021%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235099556%22%2C%22PMCID%22%3A%22PMC8982378%22%2C%22ISSN%22%3A%222160-1836%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22YJ2VT8IT%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Dell%27Aglio%20et%20al.%22%2C%22parsedDate%22%3A%222022-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDell%26%23x2019%3BAglio%2C%20D.%20D.%2C%20Mena%2C%20S.%2C%20Mauxion%2C%20R.%2C%20McMillan%2C%20W.%20O.%2C%20%26amp%3B%20Montgomery%2C%20S.%20H.%20%282022%29.%20Divergence%20in%20Heliconius%20flight%20behaviour%20is%20associated%20with%20local%20adaptation%20to%20different%20forest%20structures.%20%26lt%3Bi%26gt%3BThe%20Journal%20of%20Animal%20Ecology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B91%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20727%26%23x2013%3B737.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1365-2656.13675%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1365-2656.13675%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Divergence%20in%20Heliconius%20flight%20behaviour%20is%20associated%20with%20local%20adaptation%20to%20different%20forest%20structures%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Denise%20D.%22%2C%22lastName%22%3A%22Dell%27Aglio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sebasti%5Cu00e1n%22%2C%22lastName%22%3A%22Mena%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R%5Cu00e9mi%22%2C%22lastName%22%3A%22Mauxion%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%5D%2C%22abstractNote%22%3A%22Microhabitat%20choice%20plays%20a%20major%20role%20in%20shaping%20local%20patterns%20of%20biodiversity.%20In%20butterflies%2C%20stratification%20in%20flight%20height%20has%20an%20important%20role%20in%20maintaining%20community%20diversity.%20Despite%20its%20presumed%20importance%2C%20the%20role%20of%20behavioural%20shifts%20in%20early%20stages%20of%20speciation%20in%20response%20to%20differences%20in%20habitat%20structure%20is%20yet%20to%20be%20established.%20Here%2C%20we%20investigated%20variation%20in%20flight%20height%20behaviour%20in%20two%20closely%20related%20Heliconius%20species%2C%20H.%20erato%20cyrbia%20and%20H.%20himera%2C%20which%20produce%20viable%20hybrids%20but%20are%20isolated%20across%20an%20environmental%20gradient%2C%20spanning%20lowland%20wet%20forest%20to%20high-altitude%20scrub%20forest.%20Speciation%20in%20this%20pair%20is%20associated%20with%20strong%20assortative%20mating%2C%20but%20ecological%20isolation%20and%20local%20adaptation%20are%20also%20considered%20essential%20for%20complete%20reproductive%20isolation.%20We%20quantified%20differences%20in%20flight%20height%20and%20forest%20structure%20across%20the%20environmental%20gradient%20and%20tested%20the%20importance%20of%20resource%20distribution%20in%20explaining%20flight%20behaviour.%20We%20then%20used%20common%20garden%20experiments%20to%20test%20whether%20differences%20in%20flight%20height%20reflect%20individual%20responses%20to%20resource%20distribution%20or%20genetically%20determined%20shifts%20in%20foraging%20behaviour.%20We%20found%20that%20the%20two%20species%20fly%20at%20different%20heights%20in%20the%20wild%2C%20and%20demonstrated%20that%20this%20can%20be%20explained%20by%20differences%20in%20the%20vertical%20distribution%20of%20plant%20resources.%20In%20both%20the%20wild%20and%20captivity%2C%20H.%20himera%20choose%20to%20fly%20lower%20and%20feed%20at%20lower%20positions%2C%20closely%20mirroring%20differences%20in%20resource%20availability%20in%20the%20wild.%20Given%20expectations%20that%20foraging%20efficiency%20contributes%20to%20survival%20and%20reproductive%20success%2C%20we%20suggest%20that%20foraging%20behaviour%20may%20reflect%20local%20adaptation%20to%20divergent%20forest%20structures.%20Our%20results%20highlight%20the%20potential%20role%20of%20habitat-dependent%20divergence%20in%20behaviour%20during%20the%20early%20stages%20of%20speciation.%22%2C%22date%22%3A%222022-04%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2F1365-2656.13675%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235157315%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221365-2656%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22LS5MM6HN%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Dell%27Aglio%20et%20al.%22%2C%22parsedDate%22%3A%222022-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDell%26%23x2019%3BAglio%2C%20D.%20D.%2C%20Mena%2C%20S.%2C%20Mauxion%2C%20R.%2C%20McMillan%2C%20W.%20O.%2C%20%26amp%3B%20Montgomery%2C%20S.%20H.%20%282022%29.%20Divergence%20in%20Heliconius%20flight%20behaviour%20is%20associated%20with%20local%20adaptation%20to%20different%20forest%20structures.%20%26lt%3Bi%26gt%3BThe%20Journal%20of%20Animal%20Ecology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B91%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20727%26%23x2013%3B737.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1365-2656.13675%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2F1365-2656.13675%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Divergence%20in%20Heliconius%20flight%20behaviour%20is%20associated%20with%20local%20adaptation%20to%20different%20forest%20structures%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Denise%20D.%22%2C%22lastName%22%3A%22Dell%27Aglio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sebasti%5Cu00e1n%22%2C%22lastName%22%3A%22Mena%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R%5Cu00e9mi%22%2C%22lastName%22%3A%22Mauxion%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20H.%22%2C%22lastName%22%3A%22Montgomery%22%7D%5D%2C%22abstractNote%22%3A%22Microhabitat%20choice%20plays%20a%20major%20role%20in%20shaping%20local%20patterns%20of%20biodiversity.%20In%20butterflies%2C%20stratification%20in%20flight%20height%20has%20an%20important%20role%20in%20maintaining%20community%20diversity.%20Despite%20its%20presumed%20importance%2C%20the%20role%20of%20behavioural%20shifts%20in%20early%20stages%20of%20speciation%20in%20response%20to%20differences%20in%20habitat%20structure%20is%20yet%20to%20be%20established.%20Here%2C%20we%20investigated%20variation%20in%20flight%20height%20behaviour%20in%20two%20closely%20related%20Heliconius%20species%2C%20H.%20erato%20cyrbia%20and%20H.%20himera%2C%20which%20produce%20viable%20hybrids%20but%20are%20isolated%20across%20an%20environmental%20gradient%2C%20spanning%20lowland%20wet%20forest%20to%20high-altitude%20scrub%20forest.%20Speciation%20in%20this%20pair%20is%20associated%20with%20strong%20assortative%20mating%2C%20but%20ecological%20isolation%20and%20local%20adaptation%20are%20also%20considered%20essential%20for%20complete%20reproductive%20isolation.%20We%20quantified%20differences%20in%20flight%20height%20and%20forest%20structure%20across%20the%20environmental%20gradient%20and%20tested%20the%20importance%20of%20resource%20distribution%20in%20explaining%20flight%20behaviour.%20We%20then%20used%20common%20garden%20experiments%20to%20test%20whether%20differences%20in%20flight%20height%20reflect%20individual%20responses%20to%20resource%20distribution%20or%20genetically%20determined%20shifts%20in%20foraging%20behaviour.%20We%20found%20that%20the%20two%20species%20fly%20at%20different%20heights%20in%20the%20wild%2C%20and%20demonstrated%20that%20this%20can%20be%20explained%20by%20differences%20in%20the%20vertical%20distribution%20of%20plant%20resources.%20In%20both%20the%20wild%20and%20captivity%2C%20H.%20himera%20choose%20to%20fly%20lower%20and%20feed%20at%20lower%20positions%2C%20closely%20mirroring%20differences%20in%20resource%20availability%20in%20the%20wild.%20Given%20expectations%20that%20foraging%20efficiency%20contributes%20to%20survival%20and%20reproductive%20success%2C%20we%20suggest%20that%20foraging%20behaviour%20may%20reflect%20local%20adaptation%20to%20divergent%20forest%20structures.%20Our%20results%20highlight%20the%20potential%20role%20of%20habitat-dependent%20divergence%20in%20behaviour%20during%20the%20early%20stages%20of%20speciation.%22%2C%22date%22%3A%222022-04%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2F1365-2656.13675%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235157315%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221365-2656%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A33%3A28Z%22%7D%7D%2C%7B%22key%22%3A%22XCNI3PKV%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Schember%20and%20Halfon%22%2C%22parsedDate%22%3A%222022-02-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BSchember%2C%20I.%2C%20%26amp%3B%20Halfon%2C%20M.%20S.%20%282022%29.%20Common%20Themes%20and%20Future%20Challenges%20in%20Understanding%20Gene%20Regulatory%20Network%20Evolution.%20%26lt%3Bi%26gt%3BCells%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B11%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20510.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fcells11030510%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fcells11030510%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Common%20Themes%20and%20Future%20Challenges%20in%20Understanding%20Gene%20Regulatory%20Network%20Evolution%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabella%22%2C%22lastName%22%3A%22Schember%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marc%20S.%22%2C%22lastName%22%3A%22Halfon%22%7D%5D%2C%22abstractNote%22%3A%22A%20major%20driving%20force%20behind%20the%20evolution%20of%20species-specific%20traits%20and%20novel%20structures%20is%20alterations%20in%20gene%20regulatory%20networks%20%28GRNs%29.%20Comprehending%20evolution%20therefore%20requires%20an%20understanding%20of%20the%20nature%20of%20changes%20in%20GRN%20structure%20and%20the%20responsible%20mechanisms.%20Here%2C%20we%20review%20two%20insect%20pigmentation%20GRNs%20in%20order%20to%20examine%20common%20themes%20in%20GRN%20evolution%20and%20to%20reveal%20some%20of%20the%20challenges%20associated%20with%20investigating%20changes%20in%20GRNs%20across%20different%20evolutionary%20distances%20at%20the%20molecular%20level.%20The%20pigmentation%20GRN%20in%20Drosophila%20melanogaster%20and%20other%20drosophilids%20is%20a%20well-defined%20network%20for%20which%20studies%20from%20closely%20related%20species%20illuminate%20the%20different%20ways%20co-option%20of%20regulators%20can%20occur.%20The%20pigmentation%20GRN%20for%20butterflies%20of%20the%20Heliconius%20species%20group%20is%20less%20fully%20detailed%20but%20it%20is%20emerging%20as%20a%20useful%20model%20for%20exploring%20important%20questions%20about%20redundancy%20and%20modularity%20in%20cis-regulatory%20systems.%20Both%20GRNs%20serve%20to%20highlight%20the%20ways%20in%20which%20redeployment%20of%20trans-acting%20factors%20can%20lead%20to%20GRN%20rewiring%20and%20network%20co-option.%20To%20gain%20insight%20into%20GRN%20evolution%2C%20we%20discuss%20the%20importance%20of%20defining%20GRN%20architecture%20at%20multiple%20levels%20both%20within%20and%20between%20species%20and%20of%20utilizing%20a%20range%20of%20complementary%20approaches.%22%2C%22date%22%3A%222022-02-01%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.3390%5C%2Fcells11030510%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235159319%22%2C%22PMCID%22%3A%22PMC8834487%22%2C%22ISSN%22%3A%222073-4409%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22FTBSHMLF%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Rosser%20et%20al.%22%2C%22parsedDate%22%3A%222022-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BRosser%2C%20N.%2C%20Edelman%2C%20N.%20B.%2C%20Queste%2C%20L.%20M.%2C%20Nelson%2C%20M.%2C%20Seixas%2C%20F.%2C%20Dasmahapatra%2C%20K.%20K.%2C%20%26amp%3B%20Mallet%2C%20J.%20%282022%29.%20Complex%20basis%20of%20hybrid%20female%20sterility%20and%20Haldane%26%23x2019%3Bs%20rule%20in%20Heliconius%20butterflies%3A%20Z-linkage%20and%20epistasis.%20%26lt%3Bi%26gt%3BMolecular%20Ecology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B31%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20959%26%23x2013%3B977.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fmec.16272%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fmec.16272%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Complex%20basis%20of%20hybrid%20female%20sterility%20and%20Haldane%27s%20rule%20in%20Heliconius%20butterflies%3A%20Z-linkage%20and%20epistasis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Neil%22%2C%22lastName%22%3A%22Rosser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nathaniel%20B.%22%2C%22lastName%22%3A%22Edelman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lucie%20M.%22%2C%22lastName%22%3A%22Queste%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michaela%22%2C%22lastName%22%3A%22Nelson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fernando%22%2C%22lastName%22%3A%22Seixas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kanchon%20K.%22%2C%22lastName%22%3A%22Dasmahapatra%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%22%2C%22lastName%22%3A%22Mallet%22%7D%5D%2C%22abstractNote%22%3A%22Hybrids%20between%20species%20are%20often%20sterile%20or%20inviable.%20Hybrid%20unfitness%20usually%20evolves%20first%20in%20the%20heterogametic%20sex-a%20pattern%20known%20as%20Haldane%26%23039%3Bs%20rule.%20The%20genetics%20of%20Haldane%26%23039%3Bs%20rule%20have%20been%20extensively%20studied%20in%20species%20where%20the%20male%20is%20the%20heterogametic%20%28XX%5C%2FXY%29%20sex%2C%20but%20its%20basis%20in%20taxa%20where%20the%20female%20is%20heterogametic%20%28ZW%5C%2FZZ%29%2C%20such%20as%20Lepidoptera%20and%20birds%2C%20is%20largely%20unknown.%20Here%2C%20we%20analyse%20a%20new%20case%20of%20female%20hybrid%20sterility%20between%20geographic%20subspecies%20of%20Heliconius%20pardalinus.%20The%20two%20subspecies%20mate%20freely%20in%20captivity%2C%20but%20female%20F1%5Cu00a0hybrids%20in%20both%20directions%20of%20cross%20are%20sterile.%20Sterility%20is%20due%20to%20arrested%20development%20of%20oocytes%20after%20they%20become%20differentiated%20from%20nurse%20cells%2C%20but%20before%20yolk%20deposition.%20We%20backcrossed%20fertile%20male%20F1%5Cu00a0hybrids%20to%20parental%20females%20and%20mapped%20quantitative%20trait%20loci%20%28QTLs%29%20for%20female%20sterility.%20We%20also%20identified%20genes%20differentially%20expressed%20in%20the%20ovary%20as%20a%20function%20of%20oocyte%20development.%20The%20Z%20chromosome%20has%20a%20major%20effect%2C%20similar%20to%20the%20%26%23039%3Blarge%20X%20effect%26%23039%3B%20in%20Drosophila%2C%20with%20strong%20epistatic%20interactions%20between%20loci%20at%20either%20end%20of%20the%20Z%20chromosome%2C%20and%20between%20the%20Z%20chromosome%20and%20autosomal%20loci%20on%20chromosomes%208%20and%2020.%20By%20intersecting%20the%20list%20of%20genes%20within%20these%20QTLs%20with%20those%20differentially%20expressed%20in%20sterile%20and%20fertile%20hybrids%2C%20we%20identified%20three%20candidate%20genes%20with%20relevant%20phenotypes.%20This%20study%20is%20the%20first%20to%20characterize%20hybrid%20sterility%20using%20genome%20mapping%20in%20the%20Lepidoptera%20and%20shows%20that%20it%20is%20produced%20by%20multiple%20complex%20epistatic%20interactions%20often%20involving%20the%20sex%20chromosome%2C%20as%20predicted%20by%20the%20dominance%20theory%20of%20Haldane%26%23039%3Bs%20rule.%22%2C%22date%22%3A%222022-02%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1111%5C%2Fmec.16272%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2234779079%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221365-294X%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22KI8VD2ZC%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Hench%20et%20al.%22%2C%22parsedDate%22%3A%222022-01-25%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHench%2C%20K.%2C%20Helmkampf%2C%20M.%2C%20McMillan%2C%20W.%20O.%2C%20%26amp%3B%20Puebla%2C%20O.%20%282022%29.%20Rapid%20radiation%20in%20a%20highly%20diverse%20marine%20environment.%20%26lt%3Bi%26gt%3BProceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B119%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20e2020457119.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1073%5C%2Fpnas.2020457119%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1073%5C%2Fpnas.2020457119%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Rapid%20radiation%20in%20a%20highly%20diverse%20marine%20environment%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kosmas%22%2C%22lastName%22%3A%22Hench%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martin%22%2C%22lastName%22%3A%22Helmkampf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%20Owen%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oscar%22%2C%22lastName%22%3A%22Puebla%22%7D%5D%2C%22abstractNote%22%3A%22Rapid%20diversification%20is%20often%20observed%20when%20founding%20species%20invade%20isolated%20or%20newly%20formed%20habitats%20that%20provide%20ecological%20opportunity%20for%20adaptive%20radiation.%20However%2C%20most%20of%20the%20Earth%26%23039%3Bs%20diversity%20arose%20in%20diverse%20environments%20where%20ecological%20opportunities%20appear%20to%20be%20more%20constrained.%20Here%2C%20we%20present%20a%20striking%20example%20of%20a%20rapid%20radiation%20in%20a%20highly%20diverse%20marine%20habitat.%20The%20hamlets%2C%20a%20group%20of%20reef%20fishes%20from%20the%20wider%20Caribbean%2C%20have%20radiated%20into%20a%20stunning%20diversity%20of%20color%20patterns%20but%20show%20low%20divergence%20across%20other%20ecological%20axes.%20Although%20the%20hamlet%20lineage%20is%20%5Cu223c26%20My%20old%2C%20the%20radiation%20appears%20to%20have%20occurred%20within%20the%20last%2010%2C000%20generations%20in%20a%20burst%20of%20diversification%20that%20ranks%20among%20the%20fastest%20in%20fishes.%20As%20such%2C%20the%20hamlets%20provide%20a%20compelling%20backdrop%20to%20uncover%20the%20genomic%20elements%20associated%20with%20phenotypic%20diversification%20and%20an%20excellent%20opportunity%20to%20build%20a%20broader%20comparative%20framework%20for%20understanding%20the%20drivers%20of%20adaptive%20radiation.%20The%20analysis%20of%20170%20genomes%20suggests%20that%20color%20pattern%20diversity%20is%20generated%20by%20different%20combinations%20of%20alleles%20at%20a%20few%20large-effect%20loci.%20Such%20a%20modular%20genomic%20architecture%20of%20diversification%20has%20been%20documented%20before%20in%20Heliconius%20butterflies%2C%20capuchino%20finches%2C%20and%20munia%20finches%2C%20three%20other%20tropical%20radiations%20that%20took%20place%20in%20highly%20diverse%20and%20complex%20environments.%20The%20hamlet%20radiation%20also%20occurred%20in%20a%20context%20of%20high%20effective%20population%20size%2C%20which%20is%20typical%20of%20marine%20populations.%20This%20allows%20for%20the%20accumulation%20of%20new%20variants%20through%20mutation%20and%20the%20retention%20of%20ancestral%20genetic%20variation%2C%20both%20of%20which%20appear%20to%20be%20important%20in%20this%20radiation.%22%2C%22date%22%3A%222022-01-25%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1073%5C%2Fpnas.2020457119%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235042790%22%2C%22PMCID%22%3A%22PMC8794831%22%2C%22ISSN%22%3A%221091-6490%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22PWBCV6QY%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Ehlers%20et%20al.%22%2C%22parsedDate%22%3A%222021-12-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BEhlers%2C%20S.%2C%20Szczerbowski%2C%20D.%2C%20Harig%2C%20T.%2C%20Stell%2C%20M.%2C%20H%26%23xF6%3Btling%2C%20S.%2C%20Darragh%2C%20K.%2C%20Jiggins%2C%20C.%20D.%2C%20%26amp%3B%20Schulz%2C%20S.%20%282021%29.%20Identification%20and%20Composition%20of%20Clasper%20Scent%20Gland%20Components%20of%20the%20Butterfly%20Heliconius%20erato%20and%20Its%20Relation%20to%20Mimicry.%20%26lt%3Bi%26gt%3BChembiochem%3A%20A%20European%20Journal%20of%20Chemical%20Biology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B22%26lt%3B%5C%2Fi%26gt%3B%2823%29%2C%203300%26%23x2013%3B3313.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fcbic.202100372%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fcbic.202100372%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Identification%20and%20Composition%20of%20Clasper%20Scent%20Gland%20Components%20of%20the%20Butterfly%20Heliconius%20erato%20and%20Its%20Relation%20to%20Mimicry%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Ehlers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daiane%22%2C%22lastName%22%3A%22Szczerbowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tim%22%2C%22lastName%22%3A%22Harig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthew%22%2C%22lastName%22%3A%22Stell%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susan%22%2C%22lastName%22%3A%22H%5Cu00f6tling%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathy%22%2C%22lastName%22%3A%22Darragh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%20D.%22%2C%22lastName%22%3A%22Jiggins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefan%22%2C%22lastName%22%3A%22Schulz%22%7D%5D%2C%22abstractNote%22%3A%22The%20butterfly%20Heliconius%20erato%20occurs%20in%20various%20mimetic%20morphs.%20The%20male%20clasper%20scent%20gland%20releases%20an%20anti-aphrodisiac%20pheromone%20and%20additionally%20contains%20a%20complex%20mixture%20of%20up%20to%20350%20components%2C%20varying%20between%20individuals.%20In%20114%20samples%20of%20five%20different%20mimicry%20groups%20and%20their%20hybrids%20750%20different%20compounds%20were%20detected%20by%20gas%20chromatography%5C%2Fmass%20spectrometry%20%28GC%5C%2FMS%29.%20Many%20unknown%20components%20occurred%2C%20which%20were%20identified%20using%20their%20mass%20spectra%2C%20gas%20chromatography%5C%2Finfrared%20spectroscopy%20%28GC%5C%2FIR%29-analyses%2C%20derivatization%2C%20and%20synthesis.%20Key%20compounds%20proved%20to%20be%20various%20esters%20of%203-oxohexan-1-ol%20and%20%28Z%29-3-hexen-1-ol%20with%20%28S%29-2%2C3-dihydrofarnesoic%20acid%2C%20accompanied%20by%20a%20large%20variety%20of%20other%20esters%20with%20longer%20terpene%20acids%2C%20fatty%20acids%2C%20and%20various%20alcohols.%20In%20addition%2C%20linear%20terpenes%20with%20up%20to%20seven%20uniformly%20connected%20isoprene%20units%20occur%2C%20e.%5Cu2009g.%20farnesylfarnesol.%20A%20large%20number%20of%20the%20compounds%20have%20not%20been%20reported%20before%20from%20nature.%20Discriminant%20analyses%20of%20principal%20components%20of%20the%20gland%20contents%20showed%20that%20the%20iridescent%20mimicry%20group%20differs%20strongly%20from%20the%20other%2C%20mostly%20also%20separated%2C%20mimicry%20groups.%20Comparison%20with%20data%20from%20other%20species%20indicated%20that%20Heliconius%20recruits%20different%20biosynthetic%20pathways%20in%20a%20species-specific%20manner%20for%20semiochemical%20formation.%22%2C%22date%22%3A%222021-12-02%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fcbic.202100372%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2234547164%22%2C%22PMCID%22%3A%22PMC9293309%22%2C%22ISSN%22%3A%221439-7633%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22UQAUJ4S9%22%2C%22library%22%3A%7B%22id%22%3A166086%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A263597%2C%22username%22%3A%22mathieujoron%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmathieujoron%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Ogilvie%20et%20al.%22%2C%22parsedDate%22%3A%222021-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BOgilvie%2C%20J.%20G.%2C%20Van%20Belleghem%2C%20S.%2C%20Range%2C%20R.%2C%20Papa%2C%20R.%2C%20McMillan%2C%20O.%20W.%2C%20Chouteau%2C%20M.%2C%20%26amp%3B%20Counterman%2C%20B.%20A.%20%282021%29.%20Balanced%20polymorphisms%20and%20their%20divergence%20in%20a%20Heliconius%20butterfly.%20%26lt%3Bi%26gt%3BEcology%20and%20Evolution%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B11%26lt%3B%5C%2Fi%26gt%3B%2824%29%2C%2018319%26%23x2013%3B18330.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.8423%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fece3.8423%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Balanced%20polymorphisms%20and%20their%20divergence%20in%20a%20Heliconius%20butterfly%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20G.%22%2C%22lastName%22%3A%22Ogilvie%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Steven%22%2C%22lastName%22%3A%22Van%20Belleghem%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ryan%22%2C%22lastName%22%3A%22Range%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Riccardo%22%2C%22lastName%22%3A%22Papa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Owen%20W.%22%2C%22lastName%22%3A%22McMillan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mathieu%22%2C%22lastName%22%3A%22Chouteau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Brian%20A.%22%2C%22lastName%22%3A%22Counterman%22%7D%5D%2C%22abstractNote%22%3A%22The%20evolution%20of%20mimicry%20in%20similarly%20defended%20prey%20is%20well%20described%20by%20the%20M%5Cu00fcllerian%20mimicry%20theory%2C%20which%20predicts%20the%20convergence%20of%20warning%20patterns%20in%20order%20to%20gain%20the%20most%20protection%20from%20predators.%20However%2C%20despite%20this%20prediction%2C%20we%20can%20find%20great%20diversity%20of%20color%20patterns%20among%20M%5Cu00fcllerian%20mimics%20such%20as%20Heliconius%20butterflies%20in%20the%20neotropics.%20Furthermore%2C%20some%20species%20have%20evolved%20the%20ability%20to%20maintain%20multiple%20distinct%20warning%20patterns%20in%20single%20populations%2C%20a%20phenomenon%20known%20as%20polymorphic%20mimicry.%20The%20adaptive%20benefit%20of%20these%20polymorphisms%20is%20questionable%20since%20variation%20from%20the%20most%20common%20warning%20patterns%20is%20expected%20to%20be%20disadvantageous%20as%20novel%20signals%20are%20punished%20by%20predators%20naive%20to%20them.%20In%20this%20study%2C%20we%20use%20artificial%20butterfly%20models%20throughout%20Central%20and%20South%20America%20to%20characterize%20the%20selective%20pressures%20maintaining%20polymorphic%20mimicry%20in%20Heliconius%20doris.%20Our%20results%20highlight%20the%20complexity%20of%20positive%20frequency-dependent%20selection%2C%20the%20principal%20selective%20pressure%20driving%20convergence%20among%20M%5Cu00fcllerian%20mimics%2C%20and%20its%20impacts%20on%20interspecific%20variation%20of%20mimetic%20warning%20coloration.%20We%20further%20show%20how%20this%20selection%20regime%20can%20both%20limit%20and%20facilitate%20the%20diversification%20of%20mimetic%20traits.%22%2C%22date%22%3A%222021-12%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1002%5C%2Fece3.8423%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2235003675%22%2C%22PMCID%22%3A%22PMC8717333%22%2C%22ISSN%22%3A%222045-7758%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222023-09-05T21%3A35%3A31Z%22%7D%7D%5D%7D
Davies, W., & Saccheri, I. (2024). Evolutionary trajectory of phenological escape in a flowering plant: Mechanistic insights from bidirectional avoidance of butterfly egg-laying pressure. ECOLOGY AND EVOLUTION, 14(5). https://doi.org/10.1002/ece3.11330
Ehlers, S., Blow, R., Szczerbowski, D., Jiggins, C., & Schulz, S. (2023). Variation of Clasper Scent Gland Composition of Heliconius Butterflies from a Biodiversity Hotspot. Chembiochem: A European Journal of Chemical Biology, e202300537. https://doi.org/10.1002/cbic.202300537
Chakraborty, M., Lara, A. G., Dang, A., McCulloch, K. J., Rainbow, D., Carter, D., Ngo, L. T., Solares, E., Said, I., Corbett-Detig, R. B., Gilbert, L. E., Emerson, J. J., & Briscoe, A. D. (2023). Sex-linked gene traffic underlies the acquisition of sexually dimorphic UV color vision in Heliconius butterflies. Proceedings of the National Academy of Sciences of the United States of America, 120(33), e2301411120. https://doi.org/10.1073/pnas.2301411120
Moura, P. A., Young, F. J., Monllor, M., Cardoso, M. Z., & Montgomery, S. H. (2023). Long-term spatial memory across large spatial scales in Heliconius butterflies. Current Biology: CB, 33(15), R797–R798. https://doi.org/10.1016/j.cub.2023.06.009
Thawornwattana, Y., Huang, J., Flouri, T., Mallet, J., & Yang, Z. (2023). Inferring the Direction of Introgression Using Genomic Sequence Data. Molecular Biology and Evolution, 40(8), msad178. https://doi.org/10.1093/molbev/msad178
Hebberecht, L., Wainwright, J. B., Thompson, C., Kershenbaum, S., McMillan, W. O., & Montgomery, S. H. (2023). Plasticity and genetic effects contribute to different axes of neural divergence in a community of mimetic Heliconius butterflies. Journal of Evolutionary Biology, 36(8), 1116–1132. https://doi.org/10.1111/jeb.14188
Young, F. J., Monllor, M., McMillan, W. O., & Montgomery, S. H. (2023). Patterns of host plant use do not explain mushroom body expansion in Heliconiini butterflies. Proceedings. Biological Sciences, 290(2003), 20231155. https://doi.org/10.1098/rspb.2023.1155
Guichard, A., Legeai, F., Tagu, D., & Lemaitre, C. (2023). MTG-Link: leveraging barcode information from linked-reads to assemble specific loci. BMC Bioinformatics, 24(1), 284. https://doi.org/10.1186/s12859-023-05395-w
Couto, A., Young, F. J., Atzeni, D., Marty, S., Melo-Flórez, L., Hebberecht, L., Monllor, M., Neal, C., Cicconardi, F., McMillan, W. O., & Montgomery, S. H. (2023). Rapid expansion and visual specialisation of learning and memory centres in the brains of Heliconiini butterflies. Nature Communications, 14(1), 4024. https://doi.org/10.1038/s41467-023-39618-8
Rougemont, Q., Huber, B., Martin, S. H., Whibley, A., Estrada, C., Solano, D., Orpet, R., McMillan, W. O., Frérot, B., & Joron, M. (2023). Subtle Introgression Footprints at the End of the Speciation Continuum in a Clade of Heliconius Butterflies. Molecular Biology and Evolution, 40(7), msad166. https://doi.org/10.1093/molbev/msad166
Borrero, J., Wright, D. S., Bacquet, C. N., & Merrill, R. M. (2023). Oviposition behavior is not affected by ultraviolet light in a butterfly with sexually-dimorphic expression of a UV-sensitive opsin. Ecology and Evolution, 13(7), e10243. https://doi.org/10.1002/ece3.10243
Rivas-Sánchez, D. F., Melo-Flórez, L., Aragón, A., Pardo-Díaz, C., Salazar, C., Montgomery, S. H., & Merrill, R. M. (2023). Parallel evolution of behavior, physiology, and life history associated with altitudinal shifts in forest type in Heliconius butterflies. Evolution; International Journal of Organic Evolution, 77(6), 1458–1467. https://doi.org/10.1093/evolut/qpad062
Zhang, Y., Zhu, Q., Shao, Y., Jiang, Y., Ouyang, Y., Zhang, L., & Zhang, W. (2023). Inferring historical introgression with deep learning. Systematic Biology, syad033. https://doi.org/10.1093/sysbio/syad033
Bayala, E. X., Cisneros, I., Massardo, D., VanKuren, N. W., & Kronforst, M. R. (2023). Divergent expression of aristaless1 and aristaless2 during embryonic appendage and pupal wing development in butterflies. BMC Biology, 21(1), 104. https://doi.org/10.1186/s12915-023-01602-5
Bayala, E. X., VanKuren, N., Massardo, D., & Kronforst, M. R. (2023). aristaless1 has a dual role in appendage formation and wing color specification during butterfly development. BMC Biology, 21(1), 100. https://doi.org/10.1186/s12915-023-01601-6
Gauthier, J., Meier, J., Legeai, F., McClure, M., Whibley, A., Bretaudeau, A., Boulain, H., Parrinello, H., Mugford, S. T., Durbin, R., Zhou, C., McCarthy, S., Wheat, C. W., Piron-Prunier, F., Monsempes, C., François, M.-C., Jay, P., Noûs, C., Persyn, E., … Elias, M. (2023). First chromosome scale genomes of ithomiine butterflies (Nymphalidae: Ithomiini): Comparative models for mimicry genetic studies. Molecular Ecology Resources, 23(4), 872–885. https://doi.org/10.1111/1755-0998.13749
Moura, P. A., Cardoso, M. Z., & Montgomery, S. H. (2023). No evidence of social learning in a socially roosting butterfly in an associative learning task. Biology Letters, 19(5), 20220490. https://doi.org/10.1098/rsbl.2022.0490
Luna, N., Herrera, G., Muñoz, M., Sánchez-Herrera, M., Brown, A., Khazan, E., Pardo-Diaz, C., Ramírez, J. D., & Salazar, C. (2023). Geography shapes the microbial community in Heliconius butterflies. FEMS Microbiology Ecology, 99(4), fiad028. https://doi.org/10.1093/femsec/fiad028
Luna, N., Herrera, G., Muñoz, M., Sánchez-Herrera, M., Brown, A., Khazan, E., Pardo-Diaz, C., Ramírez, J. D., & Salazar, C. (2023). Geography shapes the microbial community in Heliconius butterflies. FEMS Microbiology Ecology, 99(4), fiad028. https://doi.org/10.1093/femsec/fiad028
Hausmann, A. E., Freire, M., Alfthan, S. A., Kuo, C.-Y., Linares, M., McMillan, O., Pardo-Diaz, C., Salazar, C., & Merrill, R. M. (2023). Does sexual conflict contribute to the evolution of novel warning patterns? Journal of Evolutionary Biology, 36(3), 563–578. https://doi.org/10.1111/jeb.14151
Bastide, H., Saenko, S. V., Chouteau, M., Joron, M., & Llaurens, V. (2023). Dominance mechanisms in supergene alleles controlling butterfly wing pattern variation: insights from gene expression in Heliconius numata. Heredity, 130(2), 92–98. https://doi.org/10.1038/s41437-022-00583-5
Srygley, R. B., Dudley, R., Hernandez, E. J., Kainz, F., Riveros, A. J., & Ellington, C. P. (2023). Quantifying the Aerodynamic Power Required for Flight and Testing for Adaptive Wind Drift in Passion-Vine Butterflies Heliconius sara (Lepidoptera: Nymphalidae). Insects, 14(2), 112. https://doi.org/10.3390/insects14020112
Rosado-Tristani, D. A., & Rodríguez-Martínez, J. A. (2023). CREPE: a Shiny app for transcription factor cataloguing. Bioinformatics Advances, 3(1), vbad055. https://doi.org/10.1093/bioadv/vbad055
Wu, N., Evans, E., van Schooten, B., Meléndez-Rosa, J., Ortiz, Y., Planas Soto-Navarro, S. M., Van Belleghem, S. M., Counterman, B. A., Papa, R., & Zhang, W. (2022). Widespread Gene Expression Divergence in Butterfly Sensory Tissues Plays a Fundamental Role During Reproductive Isolation and Speciation. Molecular Biology and Evolution, 39(11), msac225. https://doi.org/10.1093/molbev/msac225
Opler, P., Stout, T., Back, W., Zhang, J., Cong, Q., Shen, J., & Grishin, N. (2022). DNA barcodes reveal different speciation scenarios in the four North American Anthocharis Boisduval, Rambur, [Dumenil] & Graslin, [1833] (Lepidoptera: Pieridae: Pierinae: Anthocharidini) species groups. ZOOTAXA, 5194(4), 519–539. https://doi.org/10.11646/zootaxa.5194.4.3
Ruggieri, A. A., Livraghi, L., Lewis, J. J., Evans, E., Cicconardi, F., Hebberecht, L., Ortiz-Ruiz, Y., Montgomery, S. H., Ghezzi, A., Rodriguez-Martinez, J. A., Jiggins, C. D., McMillan, W. O., Counterman, B. A., Papa, R., & Van Belleghem, S. M. (2022). A butterfly pan-genome reveals that a large amount of structural variation underlies the evolution of chromatin accessibility. Genome Research, 32(10), 1862–1875. https://doi.org/10.1101/gr.276839.122
Pereira Martins, A. R., Martins, L. P., Ho, W.-Z., McMillan, W. O., Ready, J. S., & Barrett, R. (2022). Scale-dependent environmental effects on phenotypic distributions in Heliconius butterflies. Ecology and Evolution, 12(9), e9286. https://doi.org/10.1002/ece3.9286
Pereira Martins, A. R., Martins, L. P., Ho, W.-Z., McMillan, W. O., Ready, J. S., & Barrett, R. (2022). Scale-dependent environmental effects on phenotypic distributions in Heliconius butterflies. Ecology and Evolution, 12(9), e9286. https://doi.org/10.1002/ece3.9286
Thawornwattana, Y., Seixas, F. A., Yang, Z., & Mallet, J. (2022). Full-Likelihood Genomic Analysis Clarifies a Complex History of Species Divergence and Introgression: The Example of the erato-sara Group of Heliconius Butterflies. Systematic Biology, 71(5), 1159–1177. https://doi.org/10.1093/sysbio/syac009
Montejo-Kovacevich, G., Meier, J. I., Bacquet, C. N., Warren, I. A., Chan, Y. F., Kucka, M., Salazar, C., Rueda-M, N., Montgomery, S. H., McMillan, W. O., Kozak, K. M., Nadeau, N. J., Martin, S. H., & Jiggins, C. D. (2022). Repeated genetic adaptation to altitude in two tropical butterflies. Nature Communications, 13(1), 4676. https://doi.org/10.1038/s41467-022-32316-x
Jay, P., Leroy, M., Le Poul, Y., Whibley, A., Arias, M., Chouteau, M., & Joron, M. (2022). Association mapping of colour variation in a butterfly provides evidence that a supergene locks together a cluster of adaptive loci. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 377(1856), 20210193. https://doi.org/10.1098/rstb.2021.0193
Berdan, E. L., Flatt, T., Kozak, G. M., Lotterhos, K. E., & Wielstra, B. (2022). Genomic architecture of supergenes: connecting form and function. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 377(1856), 20210192. https://doi.org/10.1098/rstb.2021.0192
Cama, B., Ehlers, S., Szczerbowski, D., Thomas-Oates, J., Jiggins, C. D., Schulz, S., McMillan, W. O., & Dasmahapatra, K. K. (2022). Exploitation of an ancestral pheromone biosynthetic pathway contributes to diversification in Heliconius butterflies. Proceedings. Biological Sciences, 289(1979), 20220474. https://doi.org/10.1098/rspb.2022.0474
Brien, M. N., Enciso-Romero, J., Lloyd, V. J., Curran, E. V., Parnell, A. J., Morochz, C., Salazar, P. A., Rastas, P., Zinn, T., & Nadeau, N. J. (2022). The genetic basis of structural colour variation in mimetic Heliconius butterflies. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 377(1855), 20200505. https://doi.org/10.1098/rstb.2020.0505
Mattila, A. L. K., Jiggins, C. D., & Saastamoinen, M. (2022). Condition dependence in biosynthesized chemical defenses of an aposematic and mimetic Heliconius butterfly. Ecology and Evolution, 12(6), e9041. https://doi.org/10.1002/ece3.9041
Hebberecht, L., Melo-Flórez, L., Young, F. J., McMillan, W. O., & Montgomery, S. H. (2022). The evolution of adult pollen feeding did not alter postembryonic growth in Heliconius butterflies. Ecology and Evolution, 12(6), e8999. https://doi.org/10.1002/ece3.8999
Melo, D. J., Borges, E. O., Szczerbowski, D., Vidal, D. M., Schulz, S., & Zarbin, P. H. G. (2022). Identification and Synthesis of a Macrolide as an Anti-aphrodisiac Pheromone from Males of Heliconius erato phyllis. Organic Letters, 24(21), 3772–3775. https://doi.org/10.1021/acs.orglett.2c01160
Szczerbowski, D., Ehlers, S., Darragh, K., Jiggins, C., & Schulz, S. (2022). Head and Tail Oxidized Terpenoid Esters from Androconia of Heliconius erato Butterflies. Journal of Natural Products, 85(5), 1428–1435. https://doi.org/10.1021/acs.jnatprod.2c00300
Jay, P., & Joron, M. (2022). The double game of chromosomal inversions in a neotropical butterfly. Comptes Rendus Biologies, 345(1), 57–73. https://doi.org/10.5802/crbiol.73
Ferrari, G., Atmore, L. M., Jentoft, S., Jakobsen, K. S., Makowiecki, D., Barrett, J. H., & Star, B. (2022). An accurate assignment test for extremely low-coverage whole-genome sequence data. Molecular Ecology Resources, 22(4), 1330–1344. https://doi.org/10.1111/1755-0998.13551
McCulloch, K. J., Macias-Muñoz, A., Mortazavi, A., & Briscoe, A. D. (2022). Multiple Mechanisms of Photoreceptor Spectral Tuning in Heliconius Butterflies. Molecular Biology and Evolution, 39(4), msac067. https://doi.org/10.1093/molbev/msac067
McCulloch, K. J., Macias-Muñoz, A., Mortazavi, A., & Briscoe, A. D. (2022). Multiple Mechanisms of Photoreceptor Spectral Tuning in Heliconius Butterflies. Molecular Biology and Evolution, 39(4), msac067. https://doi.org/10.1093/molbev/msac067
Hanly, J. J., Livraghi, L., Heryanto, C., McMillan, W. O., Jiggins, C. D., Gilbert, L. E., & Martin, A. (2022). A large deletion at the cortex locus eliminates butterfly wing patterning. G3 (Bethesda, Md.), 12(4), jkac021. https://doi.org/10.1093/g3journal/jkac021
Dell’Aglio, D. D., Mena, S., Mauxion, R., McMillan, W. O., & Montgomery, S. H. (2022). Divergence in Heliconius flight behaviour is associated with local adaptation to different forest structures. The Journal of Animal Ecology, 91(4), 727–737. https://doi.org/10.1111/1365-2656.13675
Dell’Aglio, D. D., Mena, S., Mauxion, R., McMillan, W. O., & Montgomery, S. H. (2022). Divergence in Heliconius flight behaviour is associated with local adaptation to different forest structures. The Journal of Animal Ecology, 91(4), 727–737. https://doi.org/10.1111/1365-2656.13675
Schember, I., & Halfon, M. S. (2022). Common Themes and Future Challenges in Understanding Gene Regulatory Network Evolution. Cells, 11(3), 510. https://doi.org/10.3390/cells11030510
Rosser, N., Edelman, N. B., Queste, L. M., Nelson, M., Seixas, F., Dasmahapatra, K. K., & Mallet, J. (2022). Complex basis of hybrid female sterility and Haldane’s rule in Heliconius butterflies: Z-linkage and epistasis. Molecular Ecology, 31(3), 959–977. https://doi.org/10.1111/mec.16272
Hench, K., Helmkampf, M., McMillan, W. O., & Puebla, O. (2022). Rapid radiation in a highly diverse marine environment. Proceedings of the National Academy of Sciences of the United States of America, 119(4), e2020457119. https://doi.org/10.1073/pnas.2020457119
Ehlers, S., Szczerbowski, D., Harig, T., Stell, M., Hötling, S., Darragh, K., Jiggins, C. D., & Schulz, S. (2021). Identification and Composition of Clasper Scent Gland Components of the Butterfly Heliconius erato and Its Relation to Mimicry. Chembiochem: A European Journal of Chemical Biology, 22(23), 3300–3313. https://doi.org/10.1002/cbic.202100372
Ogilvie, J. G., Van Belleghem, S., Range, R., Papa, R., McMillan, O. W., Chouteau, M., & Counterman, B. A. (2021). Balanced polymorphisms and their divergence in a Heliconius butterfly. Ecology and Evolution, 11(24), 18319–18330. https://doi.org/10.1002/ece3.8423